Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054473240> ?p ?o ?g. }
- W2054473240 endingPage "431" @default.
- W2054473240 startingPage "427" @default.
- W2054473240 abstract "Reported herein are studies of the concentration and temperature dependent interactions with DNA of the stereochemically defined mixed-metal supramolecular complexes, [(tpy)Ru(tppz)PtCl](PF6)3 and [ClPt(tppz)Ru(tppz)PtCl](PF6)4 (tpy = 2,2′:6′,2′′-terpyridine and tppz = 2,3,5,6-tetrakis(2-pyridyl)pyrazine). These metal complexes couple a ruthenium based light absorber (LA) to the bioactive platinum sites (BAS) using a tridentate bridging ligand (BL). The complexes exhibit intense Ru → tppz(π∗) metal to ligand charge transfer (MLCT) transitions in the visible region and adopt a square planar geometry around the Pt(II) center. The effect of incubating these metal complexes with DNA on the subsequent migration of DNA through an agarose gel was found to be more dramatic than that observed for the well known anticancer drug, cis-[Pt(NH3)2Cl2] (cisplatin). This effect was enhanced with increased incubation temperature. Unwinding of supercoiled plasmid DNA was found to be more pronounced for the trimetallic complex, [ClPt(tppz)Ru(tppz)PtCl](PF6)4, than for the bimetallic complex, [(tpy)Ru(tppz)PtCl](PF6)3." @default.
- W2054473240 created "2016-06-24" @default.
- W2054473240 creator A5055468992 @default.
- W2054473240 creator A5064270682 @default.
- W2054473240 creator A5065284710 @default.
- W2054473240 creator A5075518492 @default.
- W2054473240 creator A5085881029 @default.
- W2054473240 date "2009-03-01" @default.
- W2054473240 modified "2023-10-17" @default.
- W2054473240 title "DNA interaction studies of tridentate bridged Ru(II)–Pt(II) mixed-metal supramolecules" @default.
- W2054473240 cites W1963980943 @default.
- W2054473240 cites W1970393749 @default.
- W2054473240 cites W1978730032 @default.
- W2054473240 cites W1980411311 @default.
- W2054473240 cites W1984269349 @default.
- W2054473240 cites W1987393218 @default.
- W2054473240 cites W1987586745 @default.
- W2054473240 cites W1990867676 @default.
- W2054473240 cites W1998089324 @default.
- W2054473240 cites W2000231152 @default.
- W2054473240 cites W2003964827 @default.
- W2054473240 cites W2008075048 @default.
- W2054473240 cites W2012108057 @default.
- W2054473240 cites W2024437480 @default.
- W2054473240 cites W2036327507 @default.
- W2054473240 cites W2045037933 @default.
- W2054473240 cites W2052752040 @default.
- W2054473240 cites W2061103770 @default.
- W2054473240 cites W2062130291 @default.
- W2054473240 cites W2064367068 @default.
- W2054473240 cites W2068395379 @default.
- W2054473240 cites W2073053678 @default.
- W2054473240 cites W2075065085 @default.
- W2054473240 cites W2087152379 @default.
- W2054473240 cites W2088342618 @default.
- W2054473240 cites W2090868344 @default.
- W2054473240 cites W2096847256 @default.
- W2054473240 cites W2126544114 @default.
- W2054473240 cites W2154244708 @default.
- W2054473240 cites W2949485030 @default.
- W2054473240 cites W4211092410 @default.
- W2054473240 doi "https://doi.org/10.1016/j.jinorgbio.2008.12.008" @default.
- W2054473240 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19187968" @default.
- W2054473240 hasPublicationYear "2009" @default.
- W2054473240 type Work @default.
- W2054473240 sameAs 2054473240 @default.
- W2054473240 citedByCount "30" @default.
- W2054473240 countsByYear W20544732402012 @default.
- W2054473240 countsByYear W20544732402013 @default.
- W2054473240 countsByYear W20544732402014 @default.
- W2054473240 countsByYear W20544732402015 @default.
- W2054473240 countsByYear W20544732402016 @default.
- W2054473240 countsByYear W20544732402017 @default.
- W2054473240 countsByYear W20544732402018 @default.
- W2054473240 countsByYear W20544732402019 @default.
- W2054473240 countsByYear W20544732402021 @default.
- W2054473240 countsByYear W20544732402022 @default.
- W2054473240 countsByYear W20544732402023 @default.
- W2054473240 crossrefType "journal-article" @default.
- W2054473240 hasAuthorship W2054473240A5055468992 @default.
- W2054473240 hasAuthorship W2054473240A5064270682 @default.
- W2054473240 hasAuthorship W2054473240A5065284710 @default.
- W2054473240 hasAuthorship W2054473240A5075518492 @default.
- W2054473240 hasAuthorship W2054473240A5085881029 @default.
- W2054473240 hasConcept C115624301 @default.
- W2054473240 hasConcept C116569031 @default.
- W2054473240 hasConcept C155647269 @default.
- W2054473240 hasConcept C161790260 @default.
- W2054473240 hasConcept C170493617 @default.
- W2054473240 hasConcept C178790620 @default.
- W2054473240 hasConcept C185592680 @default.
- W2054473240 hasConcept C2777765701 @default.
- W2054473240 hasConcept C43411465 @default.
- W2054473240 hasConcept C518104683 @default.
- W2054473240 hasConcept C544153396 @default.
- W2054473240 hasConcept C552990157 @default.
- W2054473240 hasConcept C55493867 @default.
- W2054473240 hasConcept C555196967 @default.
- W2054473240 hasConcept C71240020 @default.
- W2054473240 hasConcept C8010536 @default.
- W2054473240 hasConcept C93275456 @default.
- W2054473240 hasConceptScore W2054473240C115624301 @default.
- W2054473240 hasConceptScore W2054473240C116569031 @default.
- W2054473240 hasConceptScore W2054473240C155647269 @default.
- W2054473240 hasConceptScore W2054473240C161790260 @default.
- W2054473240 hasConceptScore W2054473240C170493617 @default.
- W2054473240 hasConceptScore W2054473240C178790620 @default.
- W2054473240 hasConceptScore W2054473240C185592680 @default.
- W2054473240 hasConceptScore W2054473240C2777765701 @default.
- W2054473240 hasConceptScore W2054473240C43411465 @default.
- W2054473240 hasConceptScore W2054473240C518104683 @default.
- W2054473240 hasConceptScore W2054473240C544153396 @default.
- W2054473240 hasConceptScore W2054473240C552990157 @default.
- W2054473240 hasConceptScore W2054473240C55493867 @default.
- W2054473240 hasConceptScore W2054473240C555196967 @default.
- W2054473240 hasConceptScore W2054473240C71240020 @default.
- W2054473240 hasConceptScore W2054473240C8010536 @default.
- W2054473240 hasConceptScore W2054473240C93275456 @default.