FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054586077> ?p ?o ?g. }

• W2054586077 endingPage "2043" @default.
• W2054586077 startingPage "2038" @default.
• W2054586077 abstract "The purpose of this study was to determine if patients with modest hyperlipidemia, and no other risk factors for coronary artery disease (CAD), have impaired endothelium-dependent (ED) vasoactivity.Hypercholesterolemia impairs ED vasodilation, but the impact of elevated triglycerides on endothelial function is not as well established.High-resolution ultrasound was used to determine flow-mediated dilation (FMD) in the brachial artery (BA) after a 5-min arterial occlusion (endothelium-dependent stimulus) and nitroglycerin-induced dilation (endothelium-independent stimulus). We studied 40 healthy controls (Group 1), 38 patients with elevated low-density lipoprotein (LDL) cholesterol (Group 2) and 35 patients with elevated triglycerides (Group 3). Patients were excluded if they had known CAD or other risk factors for CAD, or if they were receiving lipid-lowering or vasoactive medications.Control patients (Group 1) had normal LDL cholesterol (2.6+/-0.8 mmol/liter) and triglyceride levels (1.0+/-0.5 mmol/liter) compared with Group 2 (5.2+/-1.2 mmol/liter, 1.8+/-0.6 mmol/liter) and Group 3 (3.5+/-0.9 mmol/liter, 4.2+/-2.5 mmol/liter) subjects (p < 0.001). Baseline BA diameters were the same across the three groups. There was no significant attenuation of flow-mediated vasodilation (FMD) in either of the hyperlipidemic groups (Group 1: 10.9+/-5.0% vs. Group 2: 8.6+/-6.1% vs. Group 3: 9.4+/-3.9%; p = 0.14). However, nitroglycerin-induced vasodilation was mildly reduced (Group 1: 21.0+/-5.0% vs. 16.9+/-7.6% vs. 17.3+/-7.7%; p = 0.01). By multivariate analysis, after controlling for baseline diameters, only the ratio of LDL/high-density lipoprotein predicted a minor impairment in FMD.In patients free from other cardiac risk factors, modest elevations of triglycerides or LDL cholesterol do not significantly attenuate BA endothelial-dependent vasodilation. Synergism with other cardiac risk factors may be required to significantly impair endothelial function in these patients." @default.
• W2054586077 created "2016-06-24" @default.
• W2054586077 creator A5001887826 @default.
• W2054586077 creator A5075629641 @default.
• W2054586077 creator A5086458121 @default.
• W2054586077 creator A5086586779 @default.
• W2054586077 creator A5087318145 @default.
• W2054586077 date "1999-06-01" @default.
• W2054586077 modified "2023-10-13" @default.
• W2054586077 title "Impaired brachial artery endothelial function is not predicted by elevated triglycerides" @default.
• W2054586077 cites W127742586 @default.
• W2054586077 cites W1965148671 @default.
• W2054586077 cites W1969927159 @default.
• W2054586077 cites W1971261277 @default.
• W2054586077 cites W1980445357 @default.
• W2054586077 cites W1984526039 @default.
• W2054586077 cites W1987876724 @default.
• W2054586077 cites W1990800912 @default.
• W2054586077 cites W2001322138 @default.
• W2054586077 cites W2006819250 @default.
• W2054586077 cites W2007542782 @default.
• W2054586077 cites W2007737411 @default.
• W2054586077 cites W2019950065 @default.
• W2054586077 cites W2022574364 @default.
• W2054586077 cites W2027904194 @default.
• W2054586077 cites W2027973914 @default.
• W2054586077 cites W2036389244 @default.
• W2054586077 cites W2037187656 @default.
• W2054586077 cites W2037394642 @default.
• W2054586077 cites W2041074255 @default.
• W2054586077 cites W2041075406 @default.
• W2054586077 cites W2042454582 @default.
• W2054586077 cites W2043595406 @default.
• W2054586077 cites W2046197010 @default.
• W2054586077 cites W2049513613 @default.
• W2054586077 cites W2051048068 @default.
• W2054586077 cites W2052740563 @default.
• W2054586077 cites W2063506869 @default.
• W2054586077 cites W2074780913 @default.
• W2054586077 cites W2077244492 @default.
• W2054586077 cites W2077247955 @default.
• W2054586077 cites W2091181219 @default.
• W2054586077 cites W2135633069 @default.
• W2054586077 cites W2155598961 @default.
• W2054586077 cites W2164115669 @default.
• W2054586077 cites W2169182236 @default.
• W2054586077 cites W2315618879 @default.
• W2054586077 cites W2335161036 @default.
• W2054586077 cites W4248021162 @default.
• W2054586077 doi "https://doi.org/10.1016/s0735-1097(99)00104-7" @default.
• W2054586077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10362211" @default.
• W2054586077 hasPublicationYear "1999" @default.
• W2054586077 type Work @default.
• W2054586077 sameAs 2054586077 @default.
• W2054586077 citedByCount "53" @default.
• W2054586077 countsByYear W20545860772013 @default.
• W2054586077 countsByYear W20545860772014 @default.
• W2054586077 countsByYear W20545860772015 @default.
• W2054586077 countsByYear W20545860772016 @default.
• W2054586077 countsByYear W20545860772020 @default.
• W2054586077 countsByYear W20545860772021 @default.
• W2054586077 countsByYear W20545860772023 @default.
• W2054586077 crossrefType "journal-article" @default.
• W2054586077 hasAuthorship W2054586077A5001887826 @default.
• W2054586077 hasAuthorship W2054586077A5075629641 @default.
• W2054586077 hasAuthorship W2054586077A5086458121 @default.
• W2054586077 hasAuthorship W2054586077A5086586779 @default.
• W2054586077 hasAuthorship W2054586077A5087318145 @default.
• W2054586077 hasConcept C120770815 @default.
• W2054586077 hasConcept C126322002 @default.
• W2054586077 hasConcept C134018914 @default.
• W2054586077 hasConcept C164705383 @default.
• W2054586077 hasConcept C176674119 @default.
• W2054586077 hasConcept C2776992346 @default.
• W2054586077 hasConcept C2777604165 @default.
• W2054586077 hasConcept C2778163477 @default.
• W2054586077 hasConcept C2778213512 @default.
• W2054586077 hasConcept C2778913445 @default.
• W2054586077 hasConcept C2779091943 @default.
• W2054586077 hasConcept C2780972559 @default.
• W2054586077 hasConcept C555293320 @default.
• W2054586077 hasConcept C71924100 @default.
• W2054586077 hasConcept C84393581 @default.
• W2054586077 hasConceptScore W2054586077C120770815 @default.
• W2054586077 hasConceptScore W2054586077C126322002 @default.
• W2054586077 hasConceptScore W2054586077C134018914 @default.
• W2054586077 hasConceptScore W2054586077C164705383 @default.
• W2054586077 hasConceptScore W2054586077C176674119 @default.
• W2054586077 hasConceptScore W2054586077C2776992346 @default.
• W2054586077 hasConceptScore W2054586077C2777604165 @default.
• W2054586077 hasConceptScore W2054586077C2778163477 @default.
• W2054586077 hasConceptScore W2054586077C2778213512 @default.
• W2054586077 hasConceptScore W2054586077C2778913445 @default.
• W2054586077 hasConceptScore W2054586077C2779091943 @default.
• W2054586077 hasConceptScore W2054586077C2780972559 @default.
• W2054586077 hasConceptScore W2054586077C555293320 @default.
• W2054586077 hasConceptScore W2054586077C71924100 @default.
• W2054586077 hasConceptScore W2054586077C84393581 @default.

• next