FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054637867> ?p ?o ?g. }

• W2054637867 endingPage "247" @default.
• W2054637867 startingPage "242" @default.
• W2054637867 abstract "Urinary and plasma amines and amine metabolites were quantified in two individuals with Norrie disease resulting from a deletion in chromosomal region Xp11.3, recently reported to be associated with absence of the gene encoding monoamine oxidase (MAO)-A and nondetectable MAO-A activity in fibroblasts and MAO-B activity in platelets. Marked (four-to 100-fold) elevations in levels of urinary phenylethylamine, o-tyramine, and m-tyramine (which are preferential substrates for MAO-B) and marked reductions (90%) in levels of 3-methoxy-4-hydroxyphenylglycol (a deaminated metabolite of norepinephrine, a preferential substrate for MAO-A) in urine and plasma confirmed the presence of a systemic, functionally significant reduction in the activities of both MAO isozymes. The magnitude of these changes, which are equivalent to those found in subjects taking MAO-inhibiting antidepressants, suggests that early initiation of dietary and drug restrictions may be clinically important in these and other patients with X-chromosomal mutations involving MAO. These findings further support the proposition that the MAOA and MAOB genes are located in close proximity on the X chromosome. Negligible changes in the metabolites of dopamine and serotonin raise the possibility that other metabolic pathways are of importance for their production, that dietary or intestinal bacterial sources contribute substantially to the presence of these amine metabolites in urine, or both." @default.
• W2054637867 created "2016-06-24" @default.
• W2054637867 creator A5011464526 @default.
• W2054637867 creator A5016704036 @default.
• W2054637867 creator A5017056649 @default.
• W2054637867 creator A5063189075 @default.
• W2054637867 creator A5063256213 @default.
• W2054637867 creator A5063795536 @default.
• W2054637867 creator A5082034930 @default.
• W2054637867 date "1990-01-01" @default.
• W2054637867 modified "2023-09-26" @default.
• W2054637867 title "Marked Amine and Amine Metabolite Changes in Norrie Disease Patients with an X-Chromosomal Deletion Affecting Monoamine Oxidase" @default.
• W2054637867 cites W1604939446 @default.
• W2054637867 cites W1912793892 @default.
• W2054637867 cites W1979492404 @default.
• W2054637867 cites W1979814084 @default.
• W2054637867 cites W1983825547 @default.
• W2054637867 cites W1988576213 @default.
• W2054637867 cites W1992877829 @default.
• W2054637867 cites W1996478925 @default.
• W2054637867 cites W2001727865 @default.
• W2054637867 cites W2007158445 @default.
• W2054637867 cites W2009521088 @default.
• W2054637867 cites W2010257109 @default.
• W2054637867 cites W2018853173 @default.
• W2054637867 cites W2026195850 @default.
• W2054637867 cites W2030705688 @default.
• W2054637867 cites W2037568194 @default.
• W2054637867 cites W2040922044 @default.
• W2054637867 cites W2044360861 @default.
• W2054637867 cites W2048073831 @default.
• W2054637867 cites W2060507349 @default.
• W2054637867 cites W2068776261 @default.
• W2054637867 cites W2077148363 @default.
• W2054637867 cites W2082868233 @default.
• W2054637867 cites W2083873648 @default.
• W2054637867 cites W2087621691 @default.
• W2054637867 cites W2102051925 @default.
• W2054637867 cites W2119125260 @default.
• W2054637867 cites W2134996660 @default.
• W2054637867 cites W2148153854 @default.
• W2054637867 cites W2155411818 @default.
• W2054637867 cites W2276629573 @default.
• W2054637867 cites W2338614948 @default.
• W2054637867 cites W2398431572 @default.
• W2054637867 cites W2401080563 @default.
• W2054637867 cites W2483738012 @default.
• W2054637867 cites W258858061 @default.
• W2054637867 cites W2616111114 @default.
• W2054637867 cites W4256511845 @default.
• W2054637867 cites W979368335 @default.
• W2054637867 doi "https://doi.org/10.1111/j.1471-4159.1990.tb13307.x" @default.
• W2054637867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2293615" @default.
• W2054637867 hasPublicationYear "1990" @default.
• W2054637867 type Work @default.
• W2054637867 sameAs 2054637867 @default.
• W2054637867 citedByCount "53" @default.
• W2054637867 countsByYear W20546378672012 @default.
• W2054637867 countsByYear W20546378672014 @default.
• W2054637867 countsByYear W20546378672015 @default.
• W2054637867 countsByYear W20546378672016 @default.
• W2054637867 countsByYear W20546378672018 @default.
• W2054637867 countsByYear W20546378672019 @default.
• W2054637867 countsByYear W20546378672022 @default.
• W2054637867 countsByYear W20546378672023 @default.
• W2054637867 crossrefType "journal-article" @default.
• W2054637867 hasAuthorship W2054637867A5011464526 @default.
• W2054637867 hasAuthorship W2054637867A5016704036 @default.
• W2054637867 hasAuthorship W2054637867A5017056649 @default.
• W2054637867 hasAuthorship W2054637867A5063189075 @default.
• W2054637867 hasAuthorship W2054637867A5063256213 @default.
• W2054637867 hasAuthorship W2054637867A5063795536 @default.
• W2054637867 hasAuthorship W2054637867A5082034930 @default.
• W2054637867 hasConcept C114461151 @default.
• W2054637867 hasConcept C119795356 @default.
• W2054637867 hasConcept C126322002 @default.
• W2054637867 hasConcept C134018914 @default.
• W2054637867 hasConcept C170493617 @default.
• W2054637867 hasConcept C181199279 @default.
• W2054637867 hasConcept C185592680 @default.
• W2054637867 hasConcept C187714386 @default.
• W2054637867 hasConcept C2775864247 @default.
• W2054637867 hasConcept C2776024655 @default.
• W2054637867 hasConcept C2776077682 @default.
• W2054637867 hasConcept C2777477808 @default.
• W2054637867 hasConcept C2778377861 @default.
• W2054637867 hasConcept C39398028 @default.
• W2054637867 hasConcept C513476851 @default.
• W2054637867 hasConcept C55493867 @default.
• W2054637867 hasConcept C71924100 @default.
• W2054637867 hasConcept C86803240 @default.
• W2054637867 hasConceptScore W2054637867C114461151 @default.
• W2054637867 hasConceptScore W2054637867C119795356 @default.
• W2054637867 hasConceptScore W2054637867C126322002 @default.
• W2054637867 hasConceptScore W2054637867C134018914 @default.
• W2054637867 hasConceptScore W2054637867C170493617 @default.
• W2054637867 hasConceptScore W2054637867C181199279 @default.
• W2054637867 hasConceptScore W2054637867C185592680 @default.

• next