Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054657128> ?p ?o ?g. }
- W2054657128 endingPage "82" @default.
- W2054657128 startingPage "75" @default.
- W2054657128 abstract "Abstract: With increasing shortage of donor organs and changes in organ allocation systems, there is a considerable need for alternative or supportive techniques in the field of liver transplantation. Liver cell transplantation (LCT) is such an innovative technique that is especially promising for use in children, because it is less invasive than orthotopic liver transplantation (OLT). Two main indications exist: acute liver failure (ALF) and hepatic‐based inborn errors of metabolism. Ten children with ALF underwent LCT so far. One patient recovered without OLT, five were successfully bridged to OLT, and four died. Clinical improvement like reduced hyperammonemia, improved coagulation, and regression of hepatic encephalopathy occurred in the majority of patients. For the treatment of inborn errors of metabolism, experience exists with Crigler–Najjar syndrome type 1 (CNS 1, n = 5) and urea cycle disorders (UCD, n = 6). All but two patients experienced metabolic stabilization for a mean period of 9.7 months, before the majority of children underwent OLT. Whereas transplant success in CNS 1 patients can be easily monitored by plasma bilirubin levels, it is much more difficult in UCDs, where many factors can contribute to clinical deterioration. Nevertheless, these individual therapeutic attempts of LCT yielded encouraging results, and prospective studies should be initiated." @default.
- W2054657128 created "2016-06-24" @default.
- W2054657128 creator A5006706914 @default.
- W2054657128 creator A5013506503 @default.
- W2054657128 creator A5090027115 @default.
- W2054657128 date "2009-11-11" @default.
- W2054657128 modified "2023-09-23" @default.
- W2054657128 title "Liver cell transplantation in children" @default.
- W2054657128 cites W1484642675 @default.
- W2054657128 cites W1572495952 @default.
- W2054657128 cites W1600407694 @default.
- W2054657128 cites W1848248203 @default.
- W2054657128 cites W1967347732 @default.
- W2054657128 cites W1971200468 @default.
- W2054657128 cites W1977855377 @default.
- W2054657128 cites W1979686921 @default.
- W2054657128 cites W1982384048 @default.
- W2054657128 cites W1982729488 @default.
- W2054657128 cites W1986289947 @default.
- W2054657128 cites W1995234279 @default.
- W2054657128 cites W1995612506 @default.
- W2054657128 cites W1997334459 @default.
- W2054657128 cites W2000582941 @default.
- W2054657128 cites W20021108 @default.
- W2054657128 cites W2002585195 @default.
- W2054657128 cites W2003850761 @default.
- W2054657128 cites W2004489789 @default.
- W2054657128 cites W2008014618 @default.
- W2054657128 cites W2009839577 @default.
- W2054657128 cites W2011500996 @default.
- W2054657128 cites W2011602117 @default.
- W2054657128 cites W2011754993 @default.
- W2054657128 cites W2014283098 @default.
- W2054657128 cites W2016602024 @default.
- W2054657128 cites W2020756899 @default.
- W2054657128 cites W2022424839 @default.
- W2054657128 cites W2022671993 @default.
- W2054657128 cites W2024907097 @default.
- W2054657128 cites W2025596234 @default.
- W2054657128 cites W2026893878 @default.
- W2054657128 cites W2030470036 @default.
- W2054657128 cites W2031117137 @default.
- W2054657128 cites W2033901013 @default.
- W2054657128 cites W2038807691 @default.
- W2054657128 cites W2041231288 @default.
- W2054657128 cites W2042962210 @default.
- W2054657128 cites W2043965767 @default.
- W2054657128 cites W2044260115 @default.
- W2054657128 cites W2046421292 @default.
- W2054657128 cites W2047596469 @default.
- W2054657128 cites W2050864608 @default.
- W2054657128 cites W2055001863 @default.
- W2054657128 cites W2056515335 @default.
- W2054657128 cites W2057778733 @default.
- W2054657128 cites W2058848231 @default.
- W2054657128 cites W2062989633 @default.
- W2054657128 cites W2064915555 @default.
- W2054657128 cites W2065412622 @default.
- W2054657128 cites W2066030410 @default.
- W2054657128 cites W2070991874 @default.
- W2054657128 cites W2072482644 @default.
- W2054657128 cites W2072835040 @default.
- W2054657128 cites W2073232514 @default.
- W2054657128 cites W2077503741 @default.
- W2054657128 cites W2078221402 @default.
- W2054657128 cites W2081046108 @default.
- W2054657128 cites W2081583806 @default.
- W2054657128 cites W2090150300 @default.
- W2054657128 cites W2090497735 @default.
- W2054657128 cites W2091346098 @default.
- W2054657128 cites W2091495082 @default.
- W2054657128 cites W2112730584 @default.
- W2054657128 cites W2115772492 @default.
- W2054657128 cites W2124051721 @default.
- W2054657128 cites W2148530915 @default.
- W2054657128 cites W2152385965 @default.
- W2054657128 cites W2158713389 @default.
- W2054657128 cites W2170585829 @default.
- W2054657128 cites W2172893291 @default.
- W2054657128 cites W2414693326 @default.
- W2054657128 cites W4249238577 @default.
- W2054657128 cites W4251150630 @default.
- W2054657128 cites W6665279 @default.
- W2054657128 doi "https://doi.org/10.1111/j.1399-0012.2009.01113.x" @default.
- W2054657128 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19930320" @default.
- W2054657128 hasPublicationYear "2009" @default.
- W2054657128 type Work @default.
- W2054657128 sameAs 2054657128 @default.
- W2054657128 citedByCount "26" @default.
- W2054657128 countsByYear W20546571282012 @default.
- W2054657128 countsByYear W20546571282013 @default.
- W2054657128 countsByYear W20546571282014 @default.
- W2054657128 countsByYear W20546571282015 @default.
- W2054657128 countsByYear W20546571282016 @default.
- W2054657128 countsByYear W20546571282019 @default.
- W2054657128 countsByYear W20546571282020 @default.
- W2054657128 countsByYear W20546571282022 @default.
- W2054657128 countsByYear W20546571282023 @default.