Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054680060> ?p ?o ?g. }
- W2054680060 endingPage "722" @default.
- W2054680060 startingPage "706" @default.
- W2054680060 abstract "We compare clinical outcomes of paediatric patients with CNS tumours treated with protons or IMRT. CNS tumours form the second most common group of cancers in children. Radiotherapy plays a major role in the treatment of many of these patients but also contributes to late side effects in long term survivors. Radiation dose inevitably deposited in healthy tissues outside the clinical target has been linked to detrimental late effects such as neurocognitive, behavioural and vascular effects in addition to endocrine abnormalities and second tumours.A literature search was performed using keywords: protons, IMRT, CNS and paediatric. Of 189 papers retrieved, 10 were deemed relevant based on title and abstract screening. All papers directly compared outcomes from protons with photons, five papers included medulloblastoma, four papers each included craniopharyngioma and low grade gliomas and three papers included ependymoma.This review found that while proton beam therapy offered similar clinical target coverage, there was a demonstrable reduction in integral dose to normal structures.This in turn suggests the potential for superior long term outcomes for paediatric patients with CNS tumours both in terms of radiogenic second cancers and out-of-field adverse effects." @default.
- W2054680060 created "2016-06-24" @default.
- W2054680060 creator A5021075046 @default.
- W2054680060 creator A5050406487 @default.
- W2054680060 date "2015-04-28" @default.
- W2054680060 modified "2023-10-06" @default.
- W2054680060 title "Dosimetric Comparison and Potential for Improved Clinical Outcomes of Paediatric CNS Patients Treated with Protons or IMRT" @default.
- W2054680060 cites W1966416500 @default.
- W2054680060 cites W1972456074 @default.
- W2054680060 cites W1974717269 @default.
- W2054680060 cites W1976079788 @default.
- W2054680060 cites W1980879738 @default.
- W2054680060 cites W1983805637 @default.
- W2054680060 cites W1990851470 @default.
- W2054680060 cites W1991049655 @default.
- W2054680060 cites W1991251712 @default.
- W2054680060 cites W2013862573 @default.
- W2054680060 cites W2028802781 @default.
- W2054680060 cites W2036165828 @default.
- W2054680060 cites W2040151060 @default.
- W2054680060 cites W2040907399 @default.
- W2054680060 cites W2049584360 @default.
- W2054680060 cites W2054987456 @default.
- W2054680060 cites W2071155486 @default.
- W2054680060 cites W2077331155 @default.
- W2054680060 cites W2077506633 @default.
- W2054680060 cites W2080815975 @default.
- W2054680060 cites W2082249653 @default.
- W2054680060 cites W2083770395 @default.
- W2054680060 cites W2084873656 @default.
- W2054680060 cites W2103404859 @default.
- W2054680060 cites W2104484857 @default.
- W2054680060 cites W2106698471 @default.
- W2054680060 cites W2106921779 @default.
- W2054680060 cites W2107703254 @default.
- W2054680060 cites W2109588324 @default.
- W2054680060 cites W2113207830 @default.
- W2054680060 cites W2117275139 @default.
- W2054680060 cites W2117808633 @default.
- W2054680060 cites W2118865293 @default.
- W2054680060 cites W2124143747 @default.
- W2054680060 cites W2127494183 @default.
- W2054680060 cites W2127768135 @default.
- W2054680060 cites W2138289701 @default.
- W2054680060 cites W2149394488 @default.
- W2054680060 cites W2157664439 @default.
- W2054680060 cites W2161324454 @default.
- W2054680060 cites W2169811933 @default.
- W2054680060 cites W2334728986 @default.
- W2054680060 cites W4375905774 @default.
- W2054680060 doi "https://doi.org/10.3390/cancers7020706" @default.
- W2054680060 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4491680" @default.
- W2054680060 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25927402" @default.
- W2054680060 hasPublicationYear "2015" @default.
- W2054680060 type Work @default.
- W2054680060 sameAs 2054680060 @default.
- W2054680060 citedByCount "30" @default.
- W2054680060 countsByYear W20546800602014 @default.
- W2054680060 countsByYear W20546800602015 @default.
- W2054680060 countsByYear W20546800602016 @default.
- W2054680060 countsByYear W20546800602017 @default.
- W2054680060 countsByYear W20546800602018 @default.
- W2054680060 countsByYear W20546800602019 @default.
- W2054680060 countsByYear W20546800602020 @default.
- W2054680060 countsByYear W20546800602021 @default.
- W2054680060 countsByYear W20546800602022 @default.
- W2054680060 countsByYear W20546800602023 @default.
- W2054680060 crossrefType "journal-article" @default.
- W2054680060 hasAuthorship W2054680060A5021075046 @default.
- W2054680060 hasAuthorship W2054680060A5050406487 @default.
- W2054680060 hasBestOaLocation W20546800601 @default.
- W2054680060 hasConcept C118552586 @default.
- W2054680060 hasConcept C126322002 @default.
- W2054680060 hasConcept C126838900 @default.
- W2054680060 hasConcept C142724271 @default.
- W2054680060 hasConcept C169900460 @default.
- W2054680060 hasConcept C172467417 @default.
- W2054680060 hasConcept C197934379 @default.
- W2054680060 hasConcept C2777047896 @default.
- W2054680060 hasConcept C2779244869 @default.
- W2054680060 hasConcept C2780789225 @default.
- W2054680060 hasConcept C2781432949 @default.
- W2054680060 hasConcept C509974204 @default.
- W2054680060 hasConcept C71924100 @default.
- W2054680060 hasConceptScore W2054680060C118552586 @default.
- W2054680060 hasConceptScore W2054680060C126322002 @default.
- W2054680060 hasConceptScore W2054680060C126838900 @default.
- W2054680060 hasConceptScore W2054680060C142724271 @default.
- W2054680060 hasConceptScore W2054680060C169900460 @default.
- W2054680060 hasConceptScore W2054680060C172467417 @default.
- W2054680060 hasConceptScore W2054680060C197934379 @default.
- W2054680060 hasConceptScore W2054680060C2777047896 @default.
- W2054680060 hasConceptScore W2054680060C2779244869 @default.
- W2054680060 hasConceptScore W2054680060C2780789225 @default.
- W2054680060 hasConceptScore W2054680060C2781432949 @default.
- W2054680060 hasConceptScore W2054680060C509974204 @default.
- W2054680060 hasConceptScore W2054680060C71924100 @default.
- W2054680060 hasIssue "2" @default.