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- W2054684018 abstract "Alzheimer's disease (AD) is one of a number of neurodegenerative conditions including frontotemporal dementia and progressive supranuclear palsy that are associated with abnormal tau protein aggregates in neurons. Mutations in the tau gene cause familial forms of frontotemporal dementia and alleles of the tau gene have been associated with risk for progressive supranuclear palsy. However, studies evaluating whether polymorphic variation in tau is associated with AD have produced conflicting results. We investigated the role of the tau exon 2 polymorphism in a large sample of AD cases and controls and found no evidence that polymorphic variation in tau is associated AD." @default.
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- W2054684018 date "2000-04-01" @default.
- W2054684018 modified "2023-09-27" @default.
- W2054684018 title "Tau polymorphisms are not associated with Alzheimer's disease" @default.
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- W2054684018 doi "https://doi.org/10.1016/s0304-3940(00)00972-1" @default.
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