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- W2054691796 abstract "Abstract Hyperlink robust biocompatible solid‐phase microextraction (SPME) devices were prepared using continuous bed (monolithic) restricted‐access media (RAM) as the SPME capillary insert. The RAM‐based SPME approach was able to simultaneously separate proteins from a biological sample, while directly extracting the active components of caffeine, paracetamol and acetylsalicylic acid from the drug NeoCitramonum . The devices were interfaced with a CZE system and fully automated analysis for sample preconcentration, desorption, separation and quantification of analytes was evaluated. Comparative study of in‐line coupled SPME–CZE using RAM and RP capillary inserts was carried out. Using an SPME (RAM) insert, the calculated caffeine, paracetamol and acetylsalicylic acid LODs in a bovine plasma sample were 0.3, 0.8 and 1.9 ng/mL, respectively." @default.
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- W2054691796 date "2008-04-17" @default.
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- W2054691796 title "Coupling of solid‐phase microextraction continuous bed (monolithic) capillaries with capillary zone electrophoresis for direct analysis of drugs in biological fluids" @default.
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- W2054691796 doi "https://doi.org/10.1002/elps.200800046" @default.
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