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- W2054696578 abstract "Substance P (SP), the heptapeptide SP5–11 and the stable analogue (p-Glu5-MePhe8-MeGly9) SP5–11 (DiMe-C7) induce a C Ca2+-dependent release of Met5-enkephalin (MET) from slices of periaqueductal gray matter (PAG) and striatum of rats. The MET release from striatal slices is greater than that from PAG slices because of the higher MET content of striatum. Intraventricular injection of SP and of the two related peptides induce analgesia in the rat, and their analgesic potency is in line with thier capacity to release MET. Other neuropeptides which possess antinociceptive activity such as bombesin, neurotensin, vasopressin and somatostatin fail to release MET from PAG slices." @default.
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- W2054696578 date "1983-11-01" @default.
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- W2054696578 title "Substance P-induced release of Met5-Enkephalin from striatal and periaqueductal gray slices" @default.
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- W2054696578 doi "https://doi.org/10.1016/0006-8993(83)90169-5" @default.
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