FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054697799> ?p ?o ?g. }

• W2054697799 endingPage "719" @default.
• W2054697799 startingPage "713" @default.
• W2054697799 abstract "AIDS-related primary central nervous system lymphoma (AIDS PCNSL) is a rapidly fatal disease. Conventional therapeutic modalities offer little and new approaches are needed. Previous work has shown that zidovudine (AZT) in combination with other agents is active in retroviral lymphomas. Epstein-Barr virus (EBV) is detected in tumor tissue and cerebrospinal fluid of AIDS PCNSL patients. In a preliminary in vitro study we found that an Epstein-Barr virus-positive B cell line underwent apoptosis on coculture with AZT. This effect was accentuated by the addition of ganciclovir (GCV). We treated five patients with AIDS PCNSL with a regimen consisting of parenteral zidovudine (1.6 g twice daily), ganciclovir (5 mg/kg twice daily), and interleukin 2 (2 million units twice daily). Four of five had an excellent response. Two patients are alive and free of disease 22 and 13 months later; another responded on two separate occasions, 5 months apart, and the last patient responded with a 70-80% regression of tumor but could not be maintained on therapy owing to myelosuppression. We conclude that parenteral zidovudine, ganciclovir, and interleukin 2 is an active combination for AIDS-related central nervous system lymphoma." @default.
• W2054697799 created "2016-06-24" @default.
• W2054697799 creator A5002438057 @default.
• W2054697799 creator A5010913940 @default.
• W2054697799 creator A5012572593 @default.
• W2054697799 creator A5020675836 @default.
• W2054697799 creator A5036314999 @default.
• W2054697799 creator A5051268791 @default.
• W2054697799 creator A5058482261 @default.
• W2054697799 creator A5072469379 @default.
• W2054697799 creator A5075454607 @default.
• W2054697799 creator A5078348752 @default.
• W2054697799 date "1999-05-20" @default.
• W2054697799 modified "2023-09-26" @default.
• W2054697799 title "Treatment of AIDS-Related Primary Central Nervous System Lymphoma with Zidovudine, Ganciclovir, and Interleukin 2" @default.
• W2054697799 cites W1853245606 @default.
• W2054697799 cites W1975904165 @default.
• W2054697799 cites W1984961360 @default.
• W2054697799 cites W1995670792 @default.
• W2054697799 cites W2002082770 @default.
• W2054697799 cites W2011486273 @default.
• W2054697799 cites W2012875866 @default.
• W2054697799 cites W2014495031 @default.
• W2054697799 cites W2034258789 @default.
• W2054697799 cites W2040340778 @default.
• W2054697799 cites W2045309234 @default.
• W2054697799 cites W2082489992 @default.
• W2054697799 cites W2090825699 @default.
• W2054697799 cites W2114139304 @default.
• W2054697799 cites W2139818706 @default.
• W2054697799 cites W2152917332 @default.
• W2054697799 cites W2166291746 @default.
• W2054697799 cites W2264631436 @default.
• W2054697799 cites W2300911692 @default.
• W2054697799 cites W2331222889 @default.
• W2054697799 cites W2395849667 @default.
• W2054697799 cites W2466306005 @default.
• W2054697799 cites W260508585 @default.
• W2054697799 cites W4232613788 @default.
• W2054697799 cites W4239271034 @default.
• W2054697799 cites W1976714523 @default.
• W2054697799 doi "https://doi.org/10.1089/088922299310809" @default.
• W2054697799 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10357467" @default.
• W2054697799 hasPublicationYear "1999" @default.
• W2054697799 type Work @default.
• W2054697799 sameAs 2054697799 @default.
• W2054697799 citedByCount "81" @default.
• W2054697799 countsByYear W20546977992012 @default.
• W2054697799 countsByYear W20546977992013 @default.
• W2054697799 countsByYear W20546977992014 @default.
• W2054697799 countsByYear W20546977992015 @default.
• W2054697799 countsByYear W20546977992016 @default.
• W2054697799 countsByYear W20546977992017 @default.
• W2054697799 countsByYear W20546977992018 @default.
• W2054697799 countsByYear W20546977992019 @default.
• W2054697799 countsByYear W20546977992020 @default.
• W2054697799 countsByYear W20546977992021 @default.
• W2054697799 countsByYear W20546977992022 @default.
• W2054697799 crossrefType "journal-article" @default.
• W2054697799 hasAuthorship W2054697799A5002438057 @default.
• W2054697799 hasAuthorship W2054697799A5010913940 @default.
• W2054697799 hasAuthorship W2054697799A5012572593 @default.
• W2054697799 hasAuthorship W2054697799A5020675836 @default.
• W2054697799 hasAuthorship W2054697799A5036314999 @default.
• W2054697799 hasAuthorship W2054697799A5051268791 @default.
• W2054697799 hasAuthorship W2054697799A5058482261 @default.
• W2054697799 hasAuthorship W2054697799A5072469379 @default.
• W2054697799 hasAuthorship W2054697799A5075454607 @default.
• W2054697799 hasAuthorship W2054697799A5078348752 @default.
• W2054697799 hasConcept C126322002 @default.
• W2054697799 hasConcept C143998085 @default.
• W2054697799 hasConcept C203014093 @default.
• W2054697799 hasConcept C2522874641 @default.
• W2054697799 hasConcept C2776409557 @default.
• W2054697799 hasConcept C2776694085 @default.
• W2054697799 hasConcept C2777965375 @default.
• W2054697799 hasConcept C2779338263 @default.
• W2054697799 hasConcept C2779450786 @default.
• W2054697799 hasConcept C2779820661 @default.
• W2054697799 hasConcept C2780216070 @default.
• W2054697799 hasConcept C2780727368 @default.
• W2054697799 hasConcept C2781173314 @default.
• W2054697799 hasConcept C2781413609 @default.
• W2054697799 hasConcept C71924100 @default.
• W2054697799 hasConcept C90924648 @default.
• W2054697799 hasConceptScore W2054697799C126322002 @default.
• W2054697799 hasConceptScore W2054697799C143998085 @default.
• W2054697799 hasConceptScore W2054697799C203014093 @default.
• W2054697799 hasConceptScore W2054697799C2522874641 @default.
• W2054697799 hasConceptScore W2054697799C2776409557 @default.
• W2054697799 hasConceptScore W2054697799C2776694085 @default.
• W2054697799 hasConceptScore W2054697799C2777965375 @default.
• W2054697799 hasConceptScore W2054697799C2779338263 @default.
• W2054697799 hasConceptScore W2054697799C2779450786 @default.
• W2054697799 hasConceptScore W2054697799C2779820661 @default.
• W2054697799 hasConceptScore W2054697799C2780216070 @default.
• W2054697799 hasConceptScore W2054697799C2780727368 @default.
• W2054697799 hasConceptScore W2054697799C2781173314 @default.

• next