FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054702955> ?p ?o ?g. }

• W2054702955 endingPage "202" @default.
• W2054702955 startingPage "197" @default.
• W2054702955 abstract "<h3>Background</h3> <i>Aspergillus</i>-derived enzymes are widely used as dough additives in the baking industry. These enzymes may give rise to immunoglobulin (Ig)E-mediated sensitization and occupational asthma. Glucoamylase (or amyloglucosidase) is an important industrial enzyme obtained from <i>Aspergillus niger</i> and used to provide fermentable sugars for yeast to improve loaf volume and texture. <h3>Objective</h3> The aim of our study was to investigate the potential allergenic role of glucoamylase in baker's asthma. <h3>Methods</h3> We report four subjects with work-related allergic respiratory symptoms who were exposed to glucoamylase and other starch-cleaving enzymes used as baking additives. The causative role of glucoamylase in work-related asthma was investigated by immunologic tests and specific inhalation challenges (SIC). Glucoamylase allergenic components were characterized by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and immunoblotting. <h3>Results</h3> Skin prick tests to glucoamylase (10 mg/mL) gave a positive response in all patients. Further, a positive skin prick test to α-amylase was obtained in the four patients and to hemicellulase in two of them. SIC to glucoamylase elicited isolated early asthmatic responses in the three patients tested, and SIC to α-amylase elicited early asthmatic responses in two patients and a dual asthmatic response in another patient. Immunoblotting with glucoamylase showed several IgE-binding bands with molecular masses between 33 and 96 kD. IgE-inhibition assays showed scarce to moderate allergenic cross-reactivity between glucoamylase and α-amylase. <h3>Conclusions</h3> These bakers had developed IgE-mediated occupational asthma to glucoamylase and α-amylase. Fungal glucoamylase is widely used as a baking additive and this enzyme may give rise to allergic respiratory reactions among exposed workers." @default.
• W2054702955 created "2016-06-24" @default.
• W2054702955 creator A5012490295 @default.
• W2054702955 creator A5015724940 @default.
• W2054702955 creator A5021497445 @default.
• W2054702955 creator A5025399535 @default.
• W2054702955 creator A5031613590 @default.
• W2054702955 creator A5089377771 @default.
• W2054702955 date "2002-08-01" @default.
• W2054702955 modified "2023-09-27" @default.
• W2054702955 title "Glucoamylase: another fungal enzyme associated with baker's asthma" @default.
• W2054702955 cites W1978602747 @default.
• W2054702955 cites W1980297623 @default.
• W2054702955 cites W1995220473 @default.
• W2054702955 cites W1997175383 @default.
• W2054702955 cites W1997464445 @default.
• W2054702955 cites W2000125580 @default.
• W2054702955 cites W2024248790 @default.
• W2054702955 cites W2025442831 @default.
• W2054702955 cites W2028661785 @default.
• W2054702955 cites W2051740987 @default.
• W2054702955 cites W2059337850 @default.
• W2054702955 cites W2064676074 @default.
• W2054702955 cites W2067176118 @default.
• W2054702955 cites W2078156211 @default.
• W2054702955 cites W2084961650 @default.
• W2054702955 cites W2085935709 @default.
• W2054702955 cites W2087216935 @default.
• W2054702955 cites W2100837269 @default.
• W2054702955 cites W2101108802 @default.
• W2054702955 cites W2137401824 @default.
• W2054702955 cites W2159557487 @default.
• W2054702955 cites W2177608449 @default.
• W2054702955 cites W2915561031 @default.
• W2054702955 doi "https://doi.org/10.1016/s1081-1206(10)61938-2" @default.
• W2054702955 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12197578" @default.
• W2054702955 hasPublicationYear "2002" @default.
• W2054702955 type Work @default.
• W2054702955 sameAs 2054702955 @default.
• W2054702955 citedByCount "73" @default.
• W2054702955 countsByYear W20547029552013 @default.
• W2054702955 countsByYear W20547029552014 @default.
• W2054702955 countsByYear W20547029552015 @default.
• W2054702955 countsByYear W20547029552016 @default.
• W2054702955 countsByYear W20547029552017 @default.
• W2054702955 countsByYear W20547029552018 @default.
• W2054702955 countsByYear W20547029552019 @default.
• W2054702955 countsByYear W20547029552020 @default.
• W2054702955 countsByYear W20547029552021 @default.
• W2054702955 countsByYear W20547029552022 @default.
• W2054702955 countsByYear W20547029552023 @default.
• W2054702955 crossrefType "journal-article" @default.
• W2054702955 hasAuthorship W2054702955A5012490295 @default.
• W2054702955 hasAuthorship W2054702955A5015724940 @default.
• W2054702955 hasAuthorship W2054702955A5021497445 @default.
• W2054702955 hasAuthorship W2054702955A5025399535 @default.
• W2054702955 hasAuthorship W2054702955A5031613590 @default.
• W2054702955 hasAuthorship W2054702955A5089377771 @default.
• W2054702955 hasConcept C141105273 @default.
• W2054702955 hasConcept C159654299 @default.
• W2054702955 hasConcept C170835558 @default.
• W2054702955 hasConcept C181199279 @default.
• W2054702955 hasConcept C185592680 @default.
• W2054702955 hasConcept C203014093 @default.
• W2054702955 hasConcept C207480886 @default.
• W2054702955 hasConcept C2775960407 @default.
• W2054702955 hasConcept C2776042228 @default.
• W2054702955 hasConcept C2776217527 @default.
• W2054702955 hasConcept C2778781276 @default.
• W2054702955 hasConcept C2779175654 @default.
• W2054702955 hasConcept C2780510475 @default.
• W2054702955 hasConcept C55493867 @default.
• W2054702955 hasConcept C71924100 @default.
• W2054702955 hasConcept C86803240 @default.
• W2054702955 hasConcept C89423630 @default.
• W2054702955 hasConceptScore W2054702955C141105273 @default.
• W2054702955 hasConceptScore W2054702955C159654299 @default.
• W2054702955 hasConceptScore W2054702955C170835558 @default.
• W2054702955 hasConceptScore W2054702955C181199279 @default.
• W2054702955 hasConceptScore W2054702955C185592680 @default.
• W2054702955 hasConceptScore W2054702955C203014093 @default.
• W2054702955 hasConceptScore W2054702955C207480886 @default.
• W2054702955 hasConceptScore W2054702955C2775960407 @default.
• W2054702955 hasConceptScore W2054702955C2776042228 @default.
• W2054702955 hasConceptScore W2054702955C2776217527 @default.
• W2054702955 hasConceptScore W2054702955C2778781276 @default.
• W2054702955 hasConceptScore W2054702955C2779175654 @default.
• W2054702955 hasConceptScore W2054702955C2780510475 @default.
• W2054702955 hasConceptScore W2054702955C55493867 @default.
• W2054702955 hasConceptScore W2054702955C71924100 @default.
• W2054702955 hasConceptScore W2054702955C86803240 @default.
• W2054702955 hasConceptScore W2054702955C89423630 @default.
• W2054702955 hasIssue "2" @default.
• W2054702955 hasLocation W20547029551 @default.
• W2054702955 hasLocation W20547029552 @default.
• W2054702955 hasOpenAccess W2054702955 @default.
• W2054702955 hasPrimaryLocation W20547029551 @default.
• W2054702955 hasRelatedWork W1982001659 @default.

• next