Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054734963> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2054734963 endingPage "192" @default.
- W2054734963 startingPage "185" @default.
- W2054734963 abstract "Blood lymphocyte subsets of various densities from 14 healthy donors and 25 patients with solid tumors were used in tests for cytotoxicity against allogeneic or autologous tumor cells. The allogeneic combinations comprised 36 tests on 28 tumors. In these the unmanipulated total lymphocyte population was cytotoxic in one experiment. In tests with density-separated subsets, 16 experiments were positive. The lytic effect resided in the light subsets. Auto-tumor lysis was detected in 7 of 25 cases, when the total lymphocyte population was used. Eleven additional tests showed cytotoxicity with the separated subsets. The autologous tumor cells were damaged by the light lymphocytes of 15 patients. Of these patients, 6 had cytotoxic cells also in the high-density subset. In seven cases auto-tumor lysis was exerted only by the dense lymphocytes. Thus, in 13 cases the profile of auto-tumor lysis differed from that observed with the allogeneic combinations and against K562. Pretreatment of the effectors with Hu-IFN-alpha enhanced or induced cytotoxicity in the light lymphocytes, against both allogeneic and autologous tumors, while the dense subset was rarely potentiated. The autologous system may represent an immune situation and therefore it is not unexpected that the active cells should have different phenotypic characteristics from those of the operationally natural killer system." @default.
- W2054734963 created "2016-06-24" @default.
- W2054734963 creator A5006412648 @default.
- W2054734963 creator A5048637663 @default.
- W2054734963 creator A5071606703 @default.
- W2054734963 creator A5074054703 @default.
- W2054734963 date "1984-02-15" @default.
- W2054734963 modified "2023-10-05" @default.
- W2054734963 title "Lysis of tumor biopsy cells by blood lymphocyte subsets of various densities. Autologous and allogeneic studies" @default.
- W2054734963 cites W136540058 @default.
- W2054734963 cites W171900668 @default.
- W2054734963 cites W1967931508 @default.
- W2054734963 cites W1979517138 @default.
- W2054734963 cites W1980535421 @default.
- W2054734963 cites W1983294864 @default.
- W2054734963 cites W1987053775 @default.
- W2054734963 cites W1989197285 @default.
- W2054734963 cites W1992821447 @default.
- W2054734963 cites W2013082470 @default.
- W2054734963 cites W2013980549 @default.
- W2054734963 cites W2015376265 @default.
- W2054734963 cites W2042264911 @default.
- W2054734963 cites W2047560546 @default.
- W2054734963 cites W2050802204 @default.
- W2054734963 cites W2051850378 @default.
- W2054734963 cites W2075273227 @default.
- W2054734963 cites W2089566264 @default.
- W2054734963 cites W2091849232 @default.
- W2054734963 cites W2165526173 @default.
- W2054734963 cites W3669110 @default.
- W2054734963 doi "https://doi.org/10.1002/ijc.2910330206" @default.
- W2054734963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6693199" @default.
- W2054734963 hasPublicationYear "1984" @default.
- W2054734963 type Work @default.
- W2054734963 sameAs 2054734963 @default.
- W2054734963 citedByCount "18" @default.
- W2054734963 crossrefType "journal-article" @default.
- W2054734963 hasAuthorship W2054734963A5006412648 @default.
- W2054734963 hasAuthorship W2054734963A5048637663 @default.
- W2054734963 hasAuthorship W2054734963A5071606703 @default.
- W2054734963 hasAuthorship W2054734963A5074054703 @default.
- W2054734963 hasConcept C109316439 @default.
- W2054734963 hasConcept C154317977 @default.
- W2054734963 hasConcept C171122931 @default.
- W2054734963 hasConcept C182615771 @default.
- W2054734963 hasConcept C202751555 @default.
- W2054734963 hasConcept C203014093 @default.
- W2054734963 hasConcept C2522874641 @default.
- W2054734963 hasConcept C2777761686 @default.
- W2054734963 hasConcept C2778102761 @default.
- W2054734963 hasConcept C2778461978 @default.
- W2054734963 hasConcept C2908647359 @default.
- W2054734963 hasConcept C2992881475 @default.
- W2054734963 hasConcept C55493867 @default.
- W2054734963 hasConcept C57409179 @default.
- W2054734963 hasConcept C71924100 @default.
- W2054734963 hasConcept C86803240 @default.
- W2054734963 hasConcept C8891405 @default.
- W2054734963 hasConcept C99454951 @default.
- W2054734963 hasConceptScore W2054734963C109316439 @default.
- W2054734963 hasConceptScore W2054734963C154317977 @default.
- W2054734963 hasConceptScore W2054734963C171122931 @default.
- W2054734963 hasConceptScore W2054734963C182615771 @default.
- W2054734963 hasConceptScore W2054734963C202751555 @default.
- W2054734963 hasConceptScore W2054734963C203014093 @default.
- W2054734963 hasConceptScore W2054734963C2522874641 @default.
- W2054734963 hasConceptScore W2054734963C2777761686 @default.
- W2054734963 hasConceptScore W2054734963C2778102761 @default.
- W2054734963 hasConceptScore W2054734963C2778461978 @default.
- W2054734963 hasConceptScore W2054734963C2908647359 @default.
- W2054734963 hasConceptScore W2054734963C2992881475 @default.
- W2054734963 hasConceptScore W2054734963C55493867 @default.
- W2054734963 hasConceptScore W2054734963C57409179 @default.
- W2054734963 hasConceptScore W2054734963C71924100 @default.
- W2054734963 hasConceptScore W2054734963C86803240 @default.
- W2054734963 hasConceptScore W2054734963C8891405 @default.
- W2054734963 hasConceptScore W2054734963C99454951 @default.
- W2054734963 hasIssue "2" @default.
- W2054734963 hasLocation W20547349631 @default.
- W2054734963 hasLocation W20547349632 @default.
- W2054734963 hasOpenAccess W2054734963 @default.
- W2054734963 hasPrimaryLocation W20547349631 @default.
- W2054734963 hasRelatedWork W114182332 @default.
- W2054734963 hasRelatedWork W1915540322 @default.
- W2054734963 hasRelatedWork W1987419909 @default.
- W2054734963 hasRelatedWork W1987839322 @default.
- W2054734963 hasRelatedWork W2015816948 @default.
- W2054734963 hasRelatedWork W2016296153 @default.
- W2054734963 hasRelatedWork W2038272141 @default.
- W2054734963 hasRelatedWork W2048686206 @default.
- W2054734963 hasRelatedWork W2053666930 @default.
- W2054734963 hasRelatedWork W2055801484 @default.
- W2054734963 hasVolume "33" @default.
- W2054734963 isParatext "false" @default.
- W2054734963 isRetracted "false" @default.
- W2054734963 magId "2054734963" @default.
- W2054734963 workType "article" @default.