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- W2054741197 abstract "In the present study a series of novel 2,4-disubstituted thiazole derivatives containing substituted pyrazole moiety was synthesized by the reaction of 3-Aryl-1H-pyrazole-4-carbaldehyde thiosemicarbazone with 6-Bromo/H-3-(bromoacetyl)-2H-chromen-2-one/phenacyl chloride. Structures of newly synthesized compounds were characterized by spectral studies. New compounds were screened for their antibacterial studies against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa. The results revealed that compounds 7c, 8e, and 8f having 2,5-dichlorothiophene substituent and 8c, 8d having 2,4-dichlorophenyl substituent showed significant antibacterial activity against all tested microorganisms." @default.
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- W2054741197 date "2010-11-01" @default.
- W2054741197 modified "2023-10-02" @default.
- W2054741197 title "Synthesis, characterization and anti-microbial studies of some novel 2,4-disubstituted thiazoles" @default.
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- W2054741197 doi "https://doi.org/10.1016/j.ejmech.2010.07.048" @default.
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