FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054773248> ?p ?o ?g. }

• W2054773248 endingPage "7288" @default.
• W2054773248 startingPage "7269" @default.
• W2054773248 abstract "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is known to interact with a cytosolic receptor and, in turn, activate transcription of the mouse P1(450) gene. Various lengths of DNA upstream of the P1(450) gene were inserted into the pSV0-cat expression vector, with and without addition of the Harvey murine sarcoma virus (Ha-MSV) 72-bp repeat enhancer element. The constructs were cotransfected with pSV2-neo into mouse hepatoma wild-type cells and two variant cell lines. One variant is believed to result from a mutation in the P1(450) structural gene and expresses high levels of P1(450) mRNA constitutively; the other variant has a defect in nuclear translocation of the inducer-receptor complex. After selection in G418, the cells were treated with control medium, TCDD, cycloheximide, or TCDD plus cycloheximide and then assayed for chloramphenicol acetyltransferase (CAT) activity. The data are consistent with the presence of several functional regions within the upstream sequence: a promoter region, a region that is negatively autoregulated, possible repressor-binding and inducer-receptor complex-binding sites, and an upstream activation element that is required for transcriptional activation by TCDD. The Ha-MSV enhancer can substitute for this upstream activation element." @default.
• W2054773248 created "2016-06-24" @default.
• W2054773248 creator A5029237881 @default.
• W2054773248 creator A5073932699 @default.
• W2054773248 date "1985-01-01" @default.
• W2054773248 modified "2023-09-23" @default.
• W2054773248 title "Autoregulation plus upstream positive and negative control regions associated with transcriptional activation of the mouse P₁450 gene" @default.
• W2054773248 cites W1468014043 @default.
• W2054773248 cites W1486735561 @default.
• W2054773248 cites W1488985346 @default.
• W2054773248 cites W1490925667 @default.
• W2054773248 cites W1505580050 @default.
• W2054773248 cites W1508536142 @default.
• W2054773248 cites W1512266787 @default.
• W2054773248 cites W1525939685 @default.
• W2054773248 cites W1563025751 @default.
• W2054773248 cites W1584392981 @default.
• W2054773248 cites W1589382058 @default.
• W2054773248 cites W1593104797 @default.
• W2054773248 cites W1598530978 @default.
• W2054773248 cites W1794918195 @default.
• W2054773248 cites W1965868053 @default.
• W2054773248 cites W1970838061 @default.
• W2054773248 cites W1983122290 @default.
• W2054773248 cites W1986709050 @default.
• W2054773248 cites W2003595499 @default.
• W2054773248 cites W2004337971 @default.
• W2054773248 cites W2030016536 @default.
• W2054773248 cites W2031698412 @default.
• W2054773248 cites W2038635349 @default.
• W2054773248 cites W2048368181 @default.
• W2054773248 cites W2060333964 @default.
• W2054773248 cites W2063909592 @default.
• W2054773248 cites W2065279356 @default.
• W2054773248 cites W2087212202 @default.
• W2054773248 cites W2088079130 @default.
• W2054773248 cites W2113208052 @default.
• W2054773248 cites W2118929543 @default.
• W2054773248 cites W2137612234 @default.
• W2054773248 cites W21418917 @default.
• W2054773248 cites W2144206181 @default.
• W2054773248 cites W2342230255 @default.
• W2054773248 cites W2412305055 @default.
• W2054773248 cites W2419374164 @default.
• W2054773248 cites W2576734941 @default.
• W2054773248 cites W4232753163 @default.
• W2054773248 doi "https://doi.org/10.1093/nar/13.20.7269" @default.
• W2054773248 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/322043" @default.
• W2054773248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2997746" @default.
• W2054773248 hasPublicationYear "1985" @default.
• W2054773248 type Work @default.
• W2054773248 sameAs 2054773248 @default.
• W2054773248 citedByCount "172" @default.
• W2054773248 countsByYear W20547732482012 @default.
• W2054773248 countsByYear W20547732482013 @default.
• W2054773248 countsByYear W20547732482016 @default.
• W2054773248 countsByYear W20547732482017 @default.
• W2054773248 crossrefType "journal-article" @default.
• W2054773248 hasAuthorship W2054773248A5029237881 @default.
• W2054773248 hasAuthorship W2054773248A5073932699 @default.
• W2054773248 hasBestOaLocation W20547732482 @default.
• W2054773248 hasConcept C101762097 @default.
• W2054773248 hasConcept C104317684 @default.
• W2054773248 hasConcept C111936080 @default.
• W2054773248 hasConcept C132376346 @default.
• W2054773248 hasConcept C138885662 @default.
• W2054773248 hasConcept C150194340 @default.
• W2054773248 hasConcept C153911025 @default.
• W2054773248 hasConcept C158448853 @default.
• W2054773248 hasConcept C161733203 @default.
• W2054773248 hasConcept C165864922 @default.
• W2054773248 hasConcept C179926584 @default.
• W2054773248 hasConcept C192245184 @default.
• W2054773248 hasConcept C21592294 @default.
• W2054773248 hasConcept C2225953 @default.
• W2054773248 hasConcept C2778128677 @default.
• W2054773248 hasConcept C2780730277 @default.
• W2054773248 hasConcept C3675279 @default.
• W2054773248 hasConcept C41895202 @default.
• W2054773248 hasConcept C54355233 @default.
• W2054773248 hasConcept C65888428 @default.
• W2054773248 hasConcept C86803240 @default.
• W2054773248 hasConcept C95444343 @default.
• W2054773248 hasConceptScore W2054773248C101762097 @default.
• W2054773248 hasConceptScore W2054773248C104317684 @default.
• W2054773248 hasConceptScore W2054773248C111936080 @default.
• W2054773248 hasConceptScore W2054773248C132376346 @default.
• W2054773248 hasConceptScore W2054773248C138885662 @default.
• W2054773248 hasConceptScore W2054773248C150194340 @default.
• W2054773248 hasConceptScore W2054773248C153911025 @default.
• W2054773248 hasConceptScore W2054773248C158448853 @default.
• W2054773248 hasConceptScore W2054773248C161733203 @default.
• W2054773248 hasConceptScore W2054773248C165864922 @default.
• W2054773248 hasConceptScore W2054773248C179926584 @default.
• W2054773248 hasConceptScore W2054773248C192245184 @default.
• W2054773248 hasConceptScore W2054773248C21592294 @default.
• W2054773248 hasConceptScore W2054773248C2225953 @default.
• W2054773248 hasConceptScore W2054773248C2778128677 @default.

• next