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- W2054798678 abstract "Purpose For more than a decade, In-111 octreotide has been known to accumulate in meningiomas as a result of the expression of subtype 2 somatostatin receptors. Improved imaging characteristics can be expected with the recently developed radiotracer Tc-99m depreotide, which also binds to subtype 2 somatostatin receptors. Materials and Methods The authors examined a patient with intraorbital and extracranial recurrent meningioma using SPECT with Tc-99m depreotide and In-111 octreotide. The tumor-to-background ratios in the lesions were compared and the findings were correlated with histopathologic findings. Results Although the tumor-to-background ratios were higher for the In-111–labeled tracer in the largest tumor lesion (5.7 versus 3.3), SPECT with the Tc-99m–labeled compound showed a proved second site of recurrence as a result of the better resolution that can be achieved with that isotope. Conclusions SPECT with Tc-99m depreotide appears to be clinically useful for detecting recurrent meningiomas with higher resolution and may outperform In-111 octreotide imaging in patients with meningiomas." @default.
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- W2054798678 date "2002-11-01" @default.
- W2054798678 modified "2023-09-25" @default.
- W2054798678 title "Comparison of Tc-99m Depreotide and In-111 Octreotide in Recurrent Meningioma" @default.
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- W2054798678 doi "https://doi.org/10.1097/00003072-200211000-00005" @default.
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