Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054805220> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2054805220 abstract "Electron spin resonance (ESR) spectroscopy has been used in an attempt to observe free radicals which may be connected to the aging processes. Isolated lipofuscin particles from the human brain, which may act as traps for reactive ESR centers, have been studied. The lipopigments exhibit ESR signals which were attributed to metal ions. Both high-spin ferric iron and copper (II) complexes were observed. The copper resonance showed axial symmetry and the observed ESR parameters (A parallel = 185 gauss, g parallel = 2.25 and g perpendicular = 2.066) indicate that the copper ions are of the non-blue type (so-called type 2). The data suggest that the copper ions might be ligated to two nitrogen and two oxygen atoms. Ceroid particles from the brains of dogs with end-stage canine ceroid lipofuscinosis yield similar resonances involving metal complexes. The concentration of the copper ions in the lipopigments seems to increase slightly towards the end stage of life. Retinal pigment epithelial cells from the eyes of dogs with canine ceroid lipofuscinosis were grown in vitro and examined with ESR when the cells reached confluency and then after being maintained confluent for 2 weeks. The spectra indicate an accumulation of metal ions due to this aging. Phase-contrast microscopy reveals an increase in perinuclear dense bodies during the time in confluency. A weak ESR signal, compatible with an oxygen-centered radical, was also found to increase slightly during the aging period." @default.
- W2054805220 created "2016-06-24" @default.
- W2054805220 creator A5002835539 @default.
- W2054805220 creator A5003225674 @default.
- W2054805220 creator A5030558917 @default.
- W2054805220 creator A5049735452 @default.
- W2054805220 date "1983-07-01" @default.
- W2054805220 modified "2023-09-26" @default.
- W2054805220 title "Free radicals and aging. Electron spin resonance studies on neuronal lipopigments and cells grown in vitro" @default.
- W2054805220 cites W1530928192 @default.
- W2054805220 cites W1975098194 @default.
- W2054805220 cites W2015274455 @default.
- W2054805220 cites W2067553423 @default.
- W2054805220 cites W2082887407 @default.
- W2054805220 cites W2315512556 @default.
- W2054805220 cites W64958550 @default.
- W2054805220 doi "https://doi.org/10.1016/0047-6374(83)90087-8" @default.
- W2054805220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6314065" @default.
- W2054805220 hasPublicationYear "1983" @default.
- W2054805220 type Work @default.
- W2054805220 sameAs 2054805220 @default.
- W2054805220 citedByCount "15" @default.
- W2054805220 crossrefType "journal-article" @default.
- W2054805220 hasAuthorship W2054805220A5002835539 @default.
- W2054805220 hasAuthorship W2054805220A5003225674 @default.
- W2054805220 hasAuthorship W2054805220A5030558917 @default.
- W2054805220 hasAuthorship W2054805220A5049735452 @default.
- W2054805220 hasConcept C121332964 @default.
- W2054805220 hasConcept C139066938 @default.
- W2054805220 hasConcept C145148216 @default.
- W2054805220 hasConcept C178790620 @default.
- W2054805220 hasConcept C185592680 @default.
- W2054805220 hasConcept C186927785 @default.
- W2054805220 hasConcept C187961010 @default.
- W2054805220 hasConcept C46141821 @default.
- W2054805220 hasConcept C544778455 @default.
- W2054805220 hasConcept C55493867 @default.
- W2054805220 hasConcept C8010536 @default.
- W2054805220 hasConceptScore W2054805220C121332964 @default.
- W2054805220 hasConceptScore W2054805220C139066938 @default.
- W2054805220 hasConceptScore W2054805220C145148216 @default.
- W2054805220 hasConceptScore W2054805220C178790620 @default.
- W2054805220 hasConceptScore W2054805220C185592680 @default.
- W2054805220 hasConceptScore W2054805220C186927785 @default.
- W2054805220 hasConceptScore W2054805220C187961010 @default.
- W2054805220 hasConceptScore W2054805220C46141821 @default.
- W2054805220 hasConceptScore W2054805220C544778455 @default.
- W2054805220 hasConceptScore W2054805220C55493867 @default.
- W2054805220 hasConceptScore W2054805220C8010536 @default.
- W2054805220 hasLocation W20548052201 @default.
- W2054805220 hasLocation W20548052202 @default.
- W2054805220 hasOpenAccess W2054805220 @default.
- W2054805220 hasPrimaryLocation W20548052201 @default.
- W2054805220 hasRelatedWork W153083710 @default.
- W2054805220 hasRelatedWork W1965270912 @default.
- W2054805220 hasRelatedWork W1971910049 @default.
- W2054805220 hasRelatedWork W1995320198 @default.
- W2054805220 hasRelatedWork W2010334340 @default.
- W2054805220 hasRelatedWork W2015850165 @default.
- W2054805220 hasRelatedWork W2031503407 @default.
- W2054805220 hasRelatedWork W2052646615 @default.
- W2054805220 hasRelatedWork W2420649425 @default.
- W2054805220 hasRelatedWork W2504256629 @default.
- W2054805220 isParatext "false" @default.
- W2054805220 isRetracted "false" @default.
- W2054805220 magId "2054805220" @default.
- W2054805220 workType "article" @default.