Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054807115> ?p ?o ?g. }
- W2054807115 endingPage "397" @default.
- W2054807115 startingPage "387" @default.
- W2054807115 abstract "Objectives Because repetitive hematuria home screening with a chemical reagent strip can detect early stage bladder cancer (BC) in asymptomatic middle-aged and elderly men, the ability of this screening to effect earlier detection and reduce BC mortality was investigated. Methods Grades, stages, and outcomes of BCs detected by hematuria screening in 1575 men were compared with those of all newly diagnosed BCs in men age 50 years or older reported to the Wisconsin cancer registry in 1988. BC grades and stages were assigned by review of all pathology slides/blocks, and causes of deaths were determined from cancer registry records. As an additional control group, outcomes of BC cases diagnosed in men solicited to take part in screening, who declined, were also determined. Results The proportions of low-grade (grades 1 and 2) superficial (Stages Ta and T1) versus high-grade (grade 3) or invasive (Stage T2 or higher) cancers in cases detected by hematuria screening (screened cases) and those reported to the tumor registry (unscreened cases) were not significantly different (52.4% versus 47.7% in 21 screened and 56.8% versus 43.3% in 511 unscreened cases) (P > 0.20). Of the high-grade or invasive cases, however, the proportion of late stage (T2 or higher) tumors was significantly lower in the screening-detected BCs compared to unscreened ones (P = 0.007). No screened case has died of BC (3- to 9-year follow-up), whereas 16.4% of unscreened cases have within 2 years of diagnosis (P = 0.025). Twenty-three of 1940 (1.2%) men who were solicited but chose not to participate in screening were diagnosed with BC within 18 months after what would have been their last home screening date, compared with 1.3% of participants having BC detected by screening. Thus, screening participants and those who were solicited and declined had similar likelihoods of developing BC. Conclusions Hematuria home screening detects high-grade cancers before they become muscle invading and significantly reduces BC mortality." @default.
- W2054807115 created "2016-06-24" @default.
- W2054807115 creator A5018374269 @default.
- W2054807115 creator A5018615135 @default.
- W2054807115 creator A5026566554 @default.
- W2054807115 creator A5051018110 @default.
- W2054807115 creator A5052835496 @default.
- W2054807115 creator A5067682799 @default.
- W2054807115 creator A5072759658 @default.
- W2054807115 creator A5074320591 @default.
- W2054807115 creator A5075388324 @default.
- W2054807115 creator A5086844653 @default.
- W2054807115 date "1995-03-01" @default.
- W2054807115 modified "2023-10-18" @default.
- W2054807115 title "Comparison of bladder cancer outcome in men undergoing hematuria home screening versus those with standard clinical presentations" @default.
- W2054807115 cites W111977625 @default.
- W2054807115 cites W122123081 @default.
- W2054807115 cites W1426844501 @default.
- W2054807115 cites W17340865 @default.
- W2054807115 cites W191777685 @default.
- W2054807115 cites W1984501740 @default.
- W2054807115 cites W1985125673 @default.
- W2054807115 cites W1989198597 @default.
- W2054807115 cites W1991915284 @default.
- W2054807115 cites W2008666554 @default.
- W2054807115 cites W2057580189 @default.
- W2054807115 cites W2078779742 @default.
- W2054807115 cites W2081144476 @default.
- W2054807115 cites W2094331414 @default.
- W2054807115 cites W2200340312 @default.
- W2054807115 cites W2313608588 @default.
- W2054807115 cites W2395940194 @default.
- W2054807115 cites W2396846532 @default.
- W2054807115 cites W2405990584 @default.
- W2054807115 cites W2406754784 @default.
- W2054807115 cites W2409746678 @default.
- W2054807115 cites W2412966920 @default.
- W2054807115 cites W2416718950 @default.
- W2054807115 cites W2417361961 @default.
- W2054807115 cites W2417407414 @default.
- W2054807115 cites W2437728179 @default.
- W2054807115 cites W2467634160 @default.
- W2054807115 cites W2493046514 @default.
- W2054807115 cites W2888986801 @default.
- W2054807115 cites W41337129 @default.
- W2054807115 cites W84859026 @default.
- W2054807115 doi "https://doi.org/10.1016/s0090-4295(99)80006-5" @default.
- W2054807115 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7879333" @default.
- W2054807115 hasPublicationYear "1995" @default.
- W2054807115 type Work @default.
- W2054807115 sameAs 2054807115 @default.
- W2054807115 citedByCount "211" @default.
- W2054807115 countsByYear W20548071152012 @default.
- W2054807115 countsByYear W20548071152013 @default.
- W2054807115 countsByYear W20548071152014 @default.
- W2054807115 countsByYear W20548071152015 @default.
- W2054807115 countsByYear W20548071152016 @default.
- W2054807115 countsByYear W20548071152017 @default.
- W2054807115 countsByYear W20548071152018 @default.
- W2054807115 countsByYear W20548071152019 @default.
- W2054807115 countsByYear W20548071152020 @default.
- W2054807115 countsByYear W20548071152021 @default.
- W2054807115 countsByYear W20548071152022 @default.
- W2054807115 countsByYear W20548071152023 @default.
- W2054807115 crossrefType "journal-article" @default.
- W2054807115 hasAuthorship W2054807115A5018374269 @default.
- W2054807115 hasAuthorship W2054807115A5018615135 @default.
- W2054807115 hasAuthorship W2054807115A5026566554 @default.
- W2054807115 hasAuthorship W2054807115A5051018110 @default.
- W2054807115 hasAuthorship W2054807115A5052835496 @default.
- W2054807115 hasAuthorship W2054807115A5067682799 @default.
- W2054807115 hasAuthorship W2054807115A5072759658 @default.
- W2054807115 hasAuthorship W2054807115A5074320591 @default.
- W2054807115 hasAuthorship W2054807115A5075388324 @default.
- W2054807115 hasAuthorship W2054807115A5086844653 @default.
- W2054807115 hasConcept C121608353 @default.
- W2054807115 hasConcept C126322002 @default.
- W2054807115 hasConcept C141071460 @default.
- W2054807115 hasConcept C146357865 @default.
- W2054807115 hasConcept C151730666 @default.
- W2054807115 hasConcept C2777910003 @default.
- W2054807115 hasConcept C2778527826 @default.
- W2054807115 hasConcept C2780352672 @default.
- W2054807115 hasConcept C29456083 @default.
- W2054807115 hasConcept C71924100 @default.
- W2054807115 hasConcept C86803240 @default.
- W2054807115 hasConceptScore W2054807115C121608353 @default.
- W2054807115 hasConceptScore W2054807115C126322002 @default.
- W2054807115 hasConceptScore W2054807115C141071460 @default.
- W2054807115 hasConceptScore W2054807115C146357865 @default.
- W2054807115 hasConceptScore W2054807115C151730666 @default.
- W2054807115 hasConceptScore W2054807115C2777910003 @default.
- W2054807115 hasConceptScore W2054807115C2778527826 @default.
- W2054807115 hasConceptScore W2054807115C2780352672 @default.
- W2054807115 hasConceptScore W2054807115C29456083 @default.
- W2054807115 hasConceptScore W2054807115C71924100 @default.
- W2054807115 hasConceptScore W2054807115C86803240 @default.
- W2054807115 hasIssue "3" @default.