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- W2054851086 abstract "Overexpression of HOXA9 is linked to the molecular pathogenesis of acute myeloid leukaemia (AML) and myelodysplastic syndrome (MDS), conferring a poor prognosis. HOXA9 expression levels were analysed in the diagnostic bone marrow (BM) samples of 13 MDS patients. HOXA9 was expressed by CD34+ BM cells at median levels 3·1-fold higher than in CD34− cells from the same patient and at median levels 4·3-fold higher than in CD34+ cells from healthy donors. These results indicate that CD34+ cell selection is required to accurately assess the expression levels of HOXA9 and related genes in the multipotential malignant progenitor cells of MDS patients." @default.
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- W2054851086 date "2005-07-01" @default.
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- W2054851086 title "CD34+ cell selection is required to assess HOXA9 expression levels in patients with myelodysplastic syndrome" @default.
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- W2054851086 doi "https://doi.org/10.1111/j.1365-2141.2005.05555.x" @default.
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