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- W2054864314 abstract "The daily water intake was reduced in rats by subcutaneous administration of propranolol. The fluid intake after 24 h of dehydration in nephrectomized animals was decreased by propranolol. In intact rats diazepam did not modify the postdehydration water intake. Propranolol injected into subfornical organ decreased water consumption after 24 h of fluid deprivation but did not change the dipsogenic response to carbachol given in the same structure. These results suggest that a β-adrenoceptor mechanism participates in the regulation of the daily water intake. After a stimulus such as dehydration, β-blockade modifies water consumption by a non-renal mechanism. This mechanism involves neither a general depressant nervous activity nor a local anesthetic action and could be located in a periventricular structure, the subfornical organ." @default.
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- W2054864314 date "1986-07-01" @default.
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- W2054864314 title "Further evidence that a β-adrenergic mechanism regulates water intake: Role of the subfornical organ" @default.
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- W2054864314 doi "https://doi.org/10.1016/0014-2999(86)90739-9" @default.
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