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- W2054902708 abstract "Abstract Changes in the nuclear cycle were detected when roots were treated in an aqueous solution of diethyl sulfate and tritiated thymidine. The mutagen caused a blockage of DNA synthesis which in turn induced a substantial mitotic delay. The severity of the delay was associated closely with the dose of the mutagen. Diethyl sulfate induced chromosome abnormalities in very low frequencies; however, of the aberrations that were induced, practically all were of the chromatid type. In addition, the data show that chromatid breaks are initiated during the DNA synthesis phase of the nuclear cycle. In order to assess clearly the chromosome-breaking ability of a mutagen, treated roots should be sampled over a wide range of collection times to insure detection of the abnormalities." @default.
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- W2054902708 date "1971-07-01" @default.
- W2054902708 modified "2023-09-28" @default.
- W2054902708 title "Alterations in the nuclear cycle, mitotic index and chromosomes of vicia as affected by diethyl sulfate" @default.
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- W2054902708 doi "https://doi.org/10.1016/0027-5107(71)90013-3" @default.
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