FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054903287> ?p ?o ?g. }

• W2054903287 endingPage "755" @default.
• W2054903287 startingPage "731" @default.
• W2054903287 abstract "In this article, an attempt has been made to review the use of receptor stimulating pure agonist opioids in anesthesia, especially in patients with cardiovascular disease. Particular emphasis has been placed on the use of opioids in high doses to produce anesthesia, techniques that recently have become popular in cardiovascular anesthesia. A major benefit of opioid anesthesia is the cardiovascular stability obtained during induction and throughout operation, even in patients with severely impaired cardiac function. There is a considerable body of evidence to support this claim when fentanyl is used. Anesthetic doses of morphine are associated with a higher incidence of cardiovascular disturbances and other problems, and, therefore, more attention to detail is required in order to achieve adequate anesthesia and hemodynamic stability. Although other opioids have been used as sole or principal agents in anesthesia for cardiovascular surgery, none have gained widespread acceptance. Meperidine, for example, which is widely used in lower (nonanesthetic) doses as a supplement to nitrous oxide in cardiac and noncardiac surgery, has proved unsuitable because of severe hemodynamic disturbances when high doses are given. However, initial reports concerning two of the newer agonist opioids, sufentanil and alfentanil, suggest that they may prove to be suitable alternatives and perhaps provide advantages over morphine and fentanyl in patients with or without cardiovascular disease. Although cardiovascular stability usually can be assured in the chronically sick cardiac patient with opioid anesthesia, this is not always so with the healthier patient, particularly those presenting for coronary artery surgery. A frequently occurring problem in these patients is hypertension during or after sternotomy, which can result in myocardial ischemia and infarction. The incidence of severe hypertension (increases in systolic blood pressure greater than 20% of control values) can be reduced drastically by increasing the dose of opioid, e.g., up to 140 micrograms/kg of fentanyl. However, despite such large doses, some patients will continue to need treatment with vasodilators, inhalation anesthetics, or other supplements at certain periods during cardiovascular operations. The use of very large doses of opioids also will prolong postoperative respiratory depression. High doses of opioids can reduce or prevent the hormonal and metabolic responses to the stress of surgery. However, even very large doses of fentanyl or its newer analogues do not prevent marked increases in plasma catecholamine concentrations in response to cardiopulmonary bypass.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
• W2054903287 created "2016-06-24" @default.
• W2054903287 creator A5006971220 @default.
• W2054903287 creator A5007914913 @default.
• W2054903287 creator A5033710492 @default.
• W2054903287 creator A5065068951 @default.
• W2054903287 date "1984-12-01" @default.
• W2054903287 modified "2023-10-16" @default.
• W2054903287 title "Opioid Analgesics in Anesthesia" @default.
• W2054903287 doi "https://doi.org/10.1097/00000542-198412000-00018" @default.
• W2054903287 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6150663" @default.
• W2054903287 hasPublicationYear "1984" @default.
• W2054903287 type Work @default.
• W2054903287 sameAs 2054903287 @default.
• W2054903287 citedByCount "170" @default.
• W2054903287 countsByYear W20549032872012 @default.
• W2054903287 countsByYear W20549032872013 @default.
• W2054903287 countsByYear W20549032872014 @default.
• W2054903287 countsByYear W20549032872015 @default.
• W2054903287 countsByYear W20549032872016 @default.
• W2054903287 countsByYear W20549032872017 @default.
• W2054903287 countsByYear W20549032872018 @default.
• W2054903287 countsByYear W20549032872019 @default.
• W2054903287 countsByYear W20549032872020 @default.
• W2054903287 countsByYear W20549032872021 @default.
• W2054903287 countsByYear W20549032872022 @default.
• W2054903287 countsByYear W20549032872023 @default.
• W2054903287 crossrefType "journal-article" @default.
• W2054903287 hasAuthorship W2054903287A5006971220 @default.
• W2054903287 hasAuthorship W2054903287A5007914913 @default.
• W2054903287 hasAuthorship W2054903287A5033710492 @default.
• W2054903287 hasAuthorship W2054903287A5065068951 @default.
• W2054903287 hasBestOaLocation W20549032871 @default.
• W2054903287 hasConcept C126322002 @default.
• W2054903287 hasConcept C170493617 @default.
• W2054903287 hasConcept C178853913 @default.
• W2054903287 hasConcept C2775849661 @default.
• W2054903287 hasConcept C2777019824 @default.
• W2054903287 hasConcept C2777389121 @default.
• W2054903287 hasConcept C2778162923 @default.
• W2054903287 hasConcept C2781063702 @default.
• W2054903287 hasConcept C2781072394 @default.
• W2054903287 hasConcept C2781091344 @default.
• W2054903287 hasConcept C42219234 @default.
• W2054903287 hasConcept C71924100 @default.
• W2054903287 hasConceptScore W2054903287C126322002 @default.
• W2054903287 hasConceptScore W2054903287C170493617 @default.
• W2054903287 hasConceptScore W2054903287C178853913 @default.
• W2054903287 hasConceptScore W2054903287C2775849661 @default.
• W2054903287 hasConceptScore W2054903287C2777019824 @default.
• W2054903287 hasConceptScore W2054903287C2777389121 @default.
• W2054903287 hasConceptScore W2054903287C2778162923 @default.
• W2054903287 hasConceptScore W2054903287C2781063702 @default.
• W2054903287 hasConceptScore W2054903287C2781072394 @default.
• W2054903287 hasConceptScore W2054903287C2781091344 @default.
• W2054903287 hasConceptScore W2054903287C42219234 @default.
• W2054903287 hasConceptScore W2054903287C71924100 @default.
• W2054903287 hasIssue "6" @default.
• W2054903287 hasLocation W20549032871 @default.
• W2054903287 hasLocation W20549032872 @default.
• W2054903287 hasOpenAccess W2054903287 @default.
• W2054903287 hasPrimaryLocation W20549032871 @default.
• W2054903287 hasRelatedWork W2017387180 @default.
• W2054903287 hasRelatedWork W2035635165 @default.
• W2054903287 hasRelatedWork W2126949727 @default.
• W2054903287 hasRelatedWork W2157307806 @default.
• W2054903287 hasRelatedWork W2161553727 @default.
• W2054903287 hasRelatedWork W2322873536 @default.
• W2054903287 hasRelatedWork W2350564277 @default.
• W2054903287 hasRelatedWork W2367485688 @default.
• W2054903287 hasRelatedWork W2405103031 @default.
• W2054903287 hasRelatedWork W4255658219 @default.
• W2054903287 hasVolume "61" @default.
• W2054903287 isParatext "false" @default.
• W2054903287 isRetracted "false" @default.
• W2054903287 magId "2054903287" @default.
• W2054903287 workType "article" @default.