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- W2054945652 abstract "When a fluid flowing through an elastic vessel is subjected to a sudden change in pressure gradient, pressure pulses willpropagate through the fluid. Velocity of these pulse waves (PWV) can be determined by simultaneous detection of walldistension on two separate points on the vessel wall, along its trajectory. PWV depends on wall stiffness, and undercertain circumstances, wall stiffness can be calculated from the propagation velocity. Optical interferometry is a noncontactingtechnique that allows measurement of wall distension on discrete locations. In this work we propose aminiaturized dual-beam laser Doppler vibrometer (LDV) to measure wall distension simultaneously at two locations.Our dual-beam LDV is based on a single laser source and one acousto-optic modulator with as much as possible of theinterferometer optics shared among the different beams. The dual-beam LDV was used for simultaneous detection ofwall distension of several elastic vessels of different stiffness. We found that PWV as measured in elastic vessels agreeswell with theoretically expected values, and measurement precision is better than 5%. Moreover, the dual-beam LDVperforms almost as good as commercial systems for detection of PWV. The dual-beam LDV can have applications incardiovascular risk management. Stiffness of large arteries has a very good predictive value for cardiovascular diseaseand overall mortality. This parameter can be estimated from arterial PWV. Current methods to measure arterial PWVsuffer from several shortcomings. A dual-beam LDV can offer substantial advantages over existing techniques." @default.
- W2054945652 created "2016-06-24" @default.
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- W2054945652 date "2011-08-15" @default.
- W2054945652 modified "2023-09-23" @default.
- W2054945652 title "Dual-beam laser Doppler vibrometer for measurement of pulse wave velocity in elastic vessels" @default.
- W2054945652 doi "https://doi.org/10.1117/12.902813" @default.
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