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• W2054950952 abstract "Recent investigations have provided considerable new information regarding the biological role of metallothioneins. The synthesis of this protein is induced in cells by certain metals. It can tightly bind with zinc, copper, cadmium, mercury or silver reducing the availability of diffusible forms of these metals within cells and therefore decreasing their toxic potential. The metallothioneins may also have an important role in regulating the normal absorption and homeostasis of zinc and copper. It is paradoxical, however, in that a protein synthesized within the cell to reduce toxicity, may, in itself, be toxic when excreted or leaked out from the cell to the extracellular space. Further studies are required to elucidate the mechanisms involved in these effects." @default.
• W2054950952 created "2016-06-24" @default.
• W2054950952 creator A5045654062 @default.
• W2054950952 creator A5072354651 @default.
• W2054950952 date "1978-07-01" @default.
• W2054950952 modified "2023-09-26" @default.
• W2054950952 title "Metallothioneins and their role in the metabolism and toxicity of metals" @default.
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• W2054950952 doi "https://doi.org/10.1016/0024-3205(78)90317-x" @default.
• W2054950952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/355755" @default.
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