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- W2054953018 abstract "2,3-Dimethoxy-5-hydroxy-6-phytyl-and-6-farnesyl-1,4-benzoquinones (HPB and HFB) inhibit DPNH- and succin-oxidases of intact mitochondria from yeast. CoQ2 reversed the inhibition in DPNH-oxidase, but there was little or no reversal in succin-oxidase. CoQ6, the dominant CoQ of yeast, showed the same relative reversals as CoQ2. For CoQ6-deficient DPNH-oxidase, supplementation with: (a) HPB; (b) HFB; (c) HPB and CoQ6; (d) HPB and CoQ10 showed unexpected increases in activity indicating coenzymatic activity for HPB and HFB; the inhibitory effects of HPB and HFB were apparent with supplementation with CoQ2. HPB inhibited the CoQ6-deficient succin-oxidase, and also in the presence of CoQ2, CoQ6 or CoQ10." @default.
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- W2054953018 date "1971-03-01" @default.
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- W2054953018 title "Effect of hydroxy analogs of coenzyme Q on DPNH- and succin-oxidase activities of yeast mitochondria" @default.
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- W2054953018 doi "https://doi.org/10.1016/0006-291x(71)90501-8" @default.
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