Matches in SemOpenAlex for { <https://semopenalex.org/work/W2054958660> ?p ?o ?g. }
- W2054958660 endingPage "2817" @default.
- W2054958660 startingPage "2810" @default.
- W2054958660 abstract "We report a pH-dependent conformational transition in short, defined homopolymeric deoxyadenosines (dA15) from a single helical structure with stacked nucleobases at neutral pH to a double-helical, parallel-stranded duplex held together by AH+-H+A base pairs at acidic pH. Using native PAGE, 2D NMR, circular dichroism (CD) and fluorescence spectroscopy, we have characterized the two different pH dependent forms of dA15. The pH-triggered transition between the two defined helical forms of dA15 is characterized by CD and fluorescence. The kinetics of this conformational switch is found to occur on a millisecond time scale. This robust, highly reversible, pH-induced transition between the two well-defined structured states of dA15 represents a new molecular building block for the construction of quick-response, pH-switchable architectures in structural DNA nanotechnology." @default.
- W2054958660 created "2016-06-24" @default.
- W2054958660 creator A5008193848 @default.
- W2054958660 creator A5045525281 @default.
- W2054958660 creator A5045956524 @default.
- W2054958660 creator A5065783632 @default.
- W2054958660 date "2009-03-11" @default.
- W2054958660 modified "2023-10-12" @default.
- W2054958660 title "The poly dA helix: a new structural motif for high performance DNA-based molecular switches" @default.
- W2054958660 cites W1488368159 @default.
- W2054958660 cites W1493545344 @default.
- W2054958660 cites W1549584365 @default.
- W2054958660 cites W1656731888 @default.
- W2054958660 cites W1970574292 @default.
- W2054958660 cites W1977535936 @default.
- W2054958660 cites W1988021503 @default.
- W2054958660 cites W1998068779 @default.
- W2054958660 cites W2006085671 @default.
- W2054958660 cites W2010923501 @default.
- W2054958660 cites W2011428226 @default.
- W2054958660 cites W2012581219 @default.
- W2054958660 cites W2013981755 @default.
- W2054958660 cites W2018982396 @default.
- W2054958660 cites W2024988575 @default.
- W2054958660 cites W2034484350 @default.
- W2054958660 cites W2040491824 @default.
- W2054958660 cites W2040524544 @default.
- W2054958660 cites W2044765798 @default.
- W2054958660 cites W2045878013 @default.
- W2054958660 cites W2055162070 @default.
- W2054958660 cites W2055366072 @default.
- W2054958660 cites W2069612289 @default.
- W2054958660 cites W2073722866 @default.
- W2054958660 cites W2074677328 @default.
- W2054958660 cites W2076755375 @default.
- W2054958660 cites W2077679263 @default.
- W2054958660 cites W2080311192 @default.
- W2054958660 cites W2081796266 @default.
- W2054958660 cites W2083276919 @default.
- W2054958660 cites W2085936342 @default.
- W2054958660 cites W2087041897 @default.
- W2054958660 cites W2090908102 @default.
- W2054958660 cites W2091550262 @default.
- W2054958660 cites W2095886687 @default.
- W2054958660 cites W2097664578 @default.
- W2054958660 cites W2098520202 @default.
- W2054958660 cites W2119635496 @default.
- W2054958660 cites W2132629607 @default.
- W2054958660 cites W2149349980 @default.
- W2054958660 cites W2154093209 @default.
- W2054958660 cites W2172167589 @default.
- W2054958660 cites W3098911092 @default.
- W2054958660 cites W4211177570 @default.
- W2054958660 doi "https://doi.org/10.1093/nar/gkp133" @default.
- W2054958660 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2685084" @default.
- W2054958660 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19279188" @default.
- W2054958660 hasPublicationYear "2009" @default.
- W2054958660 type Work @default.
- W2054958660 sameAs 2054958660 @default.
- W2054958660 citedByCount "117" @default.
- W2054958660 countsByYear W20549586602012 @default.
- W2054958660 countsByYear W20549586602013 @default.
- W2054958660 countsByYear W20549586602014 @default.
- W2054958660 countsByYear W20549586602015 @default.
- W2054958660 countsByYear W20549586602016 @default.
- W2054958660 countsByYear W20549586602017 @default.
- W2054958660 countsByYear W20549586602018 @default.
- W2054958660 countsByYear W20549586602019 @default.
- W2054958660 countsByYear W20549586602020 @default.
- W2054958660 countsByYear W20549586602021 @default.
- W2054958660 countsByYear W20549586602022 @default.
- W2054958660 countsByYear W20549586602023 @default.
- W2054958660 crossrefType "journal-article" @default.
- W2054958660 hasAuthorship W2054958660A5008193848 @default.
- W2054958660 hasAuthorship W2054958660A5045525281 @default.
- W2054958660 hasAuthorship W2054958660A5045956524 @default.
- W2054958660 hasAuthorship W2054958660A5065783632 @default.
- W2054958660 hasBestOaLocation W20549586601 @default.
- W2054958660 hasConcept C104317684 @default.
- W2054958660 hasConcept C121332964 @default.
- W2054958660 hasConcept C12554922 @default.
- W2054958660 hasConcept C133571119 @default.
- W2054958660 hasConcept C148898269 @default.
- W2054958660 hasConcept C178790620 @default.
- W2054958660 hasConcept C185581394 @default.
- W2054958660 hasConcept C185592680 @default.
- W2054958660 hasConcept C18903297 @default.
- W2054958660 hasConcept C194232998 @default.
- W2054958660 hasConcept C2777339483 @default.
- W2054958660 hasConcept C2778530040 @default.
- W2054958660 hasConcept C2779965526 @default.
- W2054958660 hasConcept C32123652 @default.
- W2054958660 hasConcept C32909587 @default.
- W2054958660 hasConcept C552990157 @default.
- W2054958660 hasConcept C55493867 @default.
- W2054958660 hasConcept C61234307 @default.
- W2054958660 hasConcept C62520636 @default.
- W2054958660 hasConcept C66974803 @default.