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- W2054979077 abstract "Pediatrics InternationalVolume 50, Issue 1 p. 138-140 Guidelines for care of pregnant women carrying hepatitis C virus and their infants Kazuo Shiraki, Kazuo Shiraki Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 1 Hitoshi Ohto, Corresponding Author Hitoshi Ohto Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanHitoshi Ohto, MD PhD, Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, 1 Hikariga-oka, Fukushima City, Fukushima 960-1295, Japan. Email: [email protected]Search for more papers by this author 2 Noriyuki Inaba, Noriyuki Inaba Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 3 Tomoo Fujisawa, Tomoo Fujisawa Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 4 Hitoshi Tajiri, Hitoshi Tajiri Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 5 Susumu Kanzaki, Susumu Kanzaki Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 1 Akira Matsui, Akira Matsui Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 6 Tsuneo Morishima, Tsuneo Morishima Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 7 Kenji Goto, Kenji Goto Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 8 Akihiko Kimura, Akihiko Kimura Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 9 Shigeo Hino, Shigeo Hino Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 10 Kazuo Shiraki, Kazuo Shiraki Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 1 Hitoshi Ohto, Corresponding Author Hitoshi Ohto Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanHitoshi Ohto, MD PhD, Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, 1 Hikariga-oka, Fukushima City, Fukushima 960-1295, Japan. Email: [email protected]Search for more papers by this author 2 Noriyuki Inaba, Noriyuki Inaba Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 3 Tomoo Fujisawa, Tomoo Fujisawa Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 4 Hitoshi Tajiri, Hitoshi Tajiri Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 5 Susumu Kanzaki, Susumu Kanzaki Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 1 Akira Matsui, Akira Matsui Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 6 Tsuneo Morishima, Tsuneo Morishima Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 7 Kenji Goto, Kenji Goto Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 8 Akihiko Kimura, Akihiko Kimura Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 9 Shigeo Hino, Shigeo Hino Departments of1Pediatrics and 10Virology, Tottori University Faculty of Medicine, Yonago, Tottori, 2Division of Blood Transfusion and Transplantation Immunology, Fukushima Medical University Hospital, Fukushima,3Department of Obstetrics and Gynecology, Dokkyo Medical University School of Medicine, Mibu, Tochigi, 4Children’s Center for Health and Development, Yokohama East Hospital, Yokohama, Kanagawa, 5Department of Pediatrics, Osaka Prefectural General Hospital, Osaka, 6Department of Child Health, University of Tsukuba School of Medicine, Tsukuba, Ibaraki, 7Department of Pediatrics, Okayama University Graduate School of Medicine, Okayama, 8Department of Pediatrics, Nagoya City University Graduate School of Medicine, Nagoya, Aichi and 9Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Fukuoka, JapanSearch for more papers by this author 10 First published: 11 February 2008 https://doi.org/10.1111/j.1442-200X.2007.02518.xCitations: 21Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Shiraki K, Ohto H, Inada N et al. Study on mother-to-infant transmission of hepatitis C and other viruses: Summary of three years study. In: The 2002–2004 General Report of the Research Committee for Prevention of Vertical Transmission Hepatitis C Virus. Ministry of Health, Labour and Welfare of Japan, Tokyo, 2005; 1– 12. 2 Ohto H, Terazawa S, Sasaki N et al. Transmission of hepatitis C virus from mothers to infants. N. Engl. J. Med. 1994; 330: 744– 50. 3 Zanetti AR, Tanzi E, Paccagnini S et al. Mother-to-infant transmission of hepatitis C virus. Lancet 1995; 345: 289– 91. 4 Gibb DM, Goodall RL, Dunn DT et al. Mother-to-child transmission of hepatitis C virus: Evidence for preventable peripartum transmission. Lancet 2000; 356: 904– 7. 5 Okamoto M, Nagata I, Murakami J et al. Prospective evaluation of risk factors in mother-to-child transmission of hepatitis C virus high virus load, vaginal delivery, and negative anti-NS-4 antibody. J. Infect. Dis. 2000; 182: 1511– 14. 6 Tajiri H, Miyoshi Y, Funada S et al. Prospective study of mother-to-infant transmission of hepatitis C virus. Pediatr. Infect. Dis. J. 2001; 20: 10– 14. 7 European Pediatric Hepatitis C Virus Network. A significant sex – but not elective cesarean section – effect on mother-to-child transmission of hepatitis C virus infection. J. Infect. Dis. 2005; 192: 1872– 9. 8 Kage M, Ogasawara S, Kosai K et al. Hepatitis C virus RNA present in saliva but absent in breast-milk of the hepatitis carrier mother. J. Gastroenterol. Hepatol. 1997; 12: 518– 21. 9 Inui A, Fujisawa T, Sogo T et al. Different outcomes of vertical transmission of hepatitis C virus in a twin pregnancy. J. Gastroenterol. Hepatol. 2002; 17: 617– 19. 10 Ceci O, Margiotta M, Marello F et al. High rate of spontaneous viral clearance in a cohort of vertically infected hepatitis C virus infants: What lies behind? J. Hepatol. 2001: 35: 687– 8. 11 Shiraki K, Ohto H, Inaba N et al. Guidelines for the care and management of the hepatitis C virus carrier pregnant women and their newborn infants. J. Jpn. Pediatr. Soc. 2005; 109: 78– 9 (in Japanese). Citing Literature Volume50, Issue1February 2008Pages 138-140 ReferencesRelatedInformation" @default.
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