Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055014304> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2055014304 endingPage "1292" @default.
- W2055014304 startingPage "1285" @default.
- W2055014304 abstract "The subunit composition of fully reduced bovine thyroglobulin consists of two polypeptide chains with molecular weights near 300,000. These two chains have been separated on sodium dodecyl sulfate gels by electrophoresis and were referred to as S and F. The effect of incubating native bovine thyroglobulin with a commercial preparation of horseradish peroxidase resulted in the conversion of S to F (and faster migrating polypeptides). Since this reaction was independent of the presence of H2O2 and iodide, it was necessary to demonstrate that the activity was present in the peroxidase enzyme which could be identified by its heme group. When the enzyme preparation was fractionated on Sephadex G-100, the activity responsible for the conversion of S to F was not associated with the heme peak but with another protein peak which eluted later on the column. Proteolytic inhibitors, such as phenylmethyl sulfonyl fluoride and pancreatic trypsin inhibitor, caused partial inhibition of the activity responsible for the conversion of S to F, whereas inhibitors of peroxidase activity had no effect. Guinea pig thyroglobulin was less susceptible to the proteolytic activity present in the peroxidase preparation than bovine thyroglobulin. The subunit composition of guinea pig thyroglobulin is different from that of bovine, since three bands of different sizes are present. The 300,000 mol wt subunit of guinea pig thyroglobulin (band A) was largely degraded, whereas the 210,000 mol wt subunit (band B) was partially degraded and the 100,000 mol wt subunit (band C) was unaffected." @default.
- W2055014304 created "2016-06-24" @default.
- W2055014304 creator A5009327221 @default.
- W2055014304 creator A5030344944 @default.
- W2055014304 creator A5038580238 @default.
- W2055014304 creator A5044208902 @default.
- W2055014304 date "1981-04-01" @default.
- W2055014304 modified "2023-09-26" @default.
- W2055014304 title "Enzymatic Conversion of the Major Polypeptide Chains of Thyroglobulin*" @default.
- W2055014304 cites W1525206651 @default.
- W2055014304 cites W1552246577 @default.
- W2055014304 cites W1600060966 @default.
- W2055014304 cites W1625660792 @default.
- W2055014304 cites W1775749144 @default.
- W2055014304 cites W1991760918 @default.
- W2055014304 cites W1991941406 @default.
- W2055014304 cites W1992940910 @default.
- W2055014304 cites W2019910161 @default.
- W2055014304 cites W202175617 @default.
- W2055014304 cites W2032453247 @default.
- W2055014304 cites W2084648839 @default.
- W2055014304 cites W2148951647 @default.
- W2055014304 doi "https://doi.org/10.1210/endo-108-4-1285" @default.
- W2055014304 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7472269" @default.
- W2055014304 hasPublicationYear "1981" @default.
- W2055014304 type Work @default.
- W2055014304 sameAs 2055014304 @default.
- W2055014304 citedByCount "6" @default.
- W2055014304 crossrefType "journal-article" @default.
- W2055014304 hasAuthorship W2055014304A5009327221 @default.
- W2055014304 hasAuthorship W2055014304A5030344944 @default.
- W2055014304 hasAuthorship W2055014304A5038580238 @default.
- W2055014304 hasAuthorship W2055014304A5044208902 @default.
- W2055014304 hasBestOaLocation W20550143041 @default.
- W2055014304 hasConcept C104292427 @default.
- W2055014304 hasConcept C104317684 @default.
- W2055014304 hasConcept C134018914 @default.
- W2055014304 hasConcept C153911025 @default.
- W2055014304 hasConcept C162008176 @default.
- W2055014304 hasConcept C163994747 @default.
- W2055014304 hasConcept C180650514 @default.
- W2055014304 hasConcept C181199279 @default.
- W2055014304 hasConcept C185592680 @default.
- W2055014304 hasConcept C2776217839 @default.
- W2055014304 hasConcept C2777676563 @default.
- W2055014304 hasConcept C2778815084 @default.
- W2055014304 hasConcept C2778835679 @default.
- W2055014304 hasConcept C2778913249 @default.
- W2055014304 hasConcept C2780340462 @default.
- W2055014304 hasConcept C3019223276 @default.
- W2055014304 hasConcept C43617362 @default.
- W2055014304 hasConcept C526584372 @default.
- W2055014304 hasConcept C55493867 @default.
- W2055014304 hasConcept C71315377 @default.
- W2055014304 hasConcept C86803240 @default.
- W2055014304 hasConceptScore W2055014304C104292427 @default.
- W2055014304 hasConceptScore W2055014304C104317684 @default.
- W2055014304 hasConceptScore W2055014304C134018914 @default.
- W2055014304 hasConceptScore W2055014304C153911025 @default.
- W2055014304 hasConceptScore W2055014304C162008176 @default.
- W2055014304 hasConceptScore W2055014304C163994747 @default.
- W2055014304 hasConceptScore W2055014304C180650514 @default.
- W2055014304 hasConceptScore W2055014304C181199279 @default.
- W2055014304 hasConceptScore W2055014304C185592680 @default.
- W2055014304 hasConceptScore W2055014304C2776217839 @default.
- W2055014304 hasConceptScore W2055014304C2777676563 @default.
- W2055014304 hasConceptScore W2055014304C2778815084 @default.
- W2055014304 hasConceptScore W2055014304C2778835679 @default.
- W2055014304 hasConceptScore W2055014304C2778913249 @default.
- W2055014304 hasConceptScore W2055014304C2780340462 @default.
- W2055014304 hasConceptScore W2055014304C3019223276 @default.
- W2055014304 hasConceptScore W2055014304C43617362 @default.
- W2055014304 hasConceptScore W2055014304C526584372 @default.
- W2055014304 hasConceptScore W2055014304C55493867 @default.
- W2055014304 hasConceptScore W2055014304C71315377 @default.
- W2055014304 hasConceptScore W2055014304C86803240 @default.
- W2055014304 hasIssue "4" @default.
- W2055014304 hasLocation W20550143041 @default.
- W2055014304 hasLocation W20550143042 @default.
- W2055014304 hasOpenAccess W2055014304 @default.
- W2055014304 hasPrimaryLocation W20550143041 @default.
- W2055014304 hasRelatedWork W1134260427 @default.
- W2055014304 hasRelatedWork W1950465592 @default.
- W2055014304 hasRelatedWork W1995541733 @default.
- W2055014304 hasRelatedWork W2025565973 @default.
- W2055014304 hasRelatedWork W2055014304 @default.
- W2055014304 hasRelatedWork W2086699247 @default.
- W2055014304 hasRelatedWork W2253598293 @default.
- W2055014304 hasRelatedWork W2436552255 @default.
- W2055014304 hasRelatedWork W2925136660 @default.
- W2055014304 hasRelatedWork W49185425 @default.
- W2055014304 hasVolume "108" @default.
- W2055014304 isParatext "false" @default.
- W2055014304 isRetracted "false" @default.
- W2055014304 magId "2055014304" @default.
- W2055014304 workType "article" @default.