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- W2055142765 endingPage "451" @default.
- W2055142765 startingPage "443" @default.
- W2055142765 abstract "The purpose of this review is to summarize recent studies that investigated the role of ghrelin and ghrelin analogs in wasting conditions.Numerous studies have demonstrated potential beneficial effects exerted by ghrelin in a number of diseases associated with wasting. Besides ghrelin's orexigenic effect, anabolic as well as anti-inflammatory activity mediated by ghrelin have been investigated in wasting conditions such as cancer, diabetes mellitus, malabsorptive diseases, chronic obstructive pulmonary disease, anorexia nervosa, renal failure, liver failure, and chronic heart failure. Encouraging results have been obtained from experimental studies and a few clinical trials using subcutaneous administration of ghrelin and ghrelin agonists in cachexia. In-vitro studies have shown ghrelin and des-acyl ghrelin biological activities on proliferation of tumor cells and abnormal tissues.The recent studies support the possible positive effects of ghrelin in therapeutic approaches and adjunct treatment of a number of diseases associated with wasting. Utilization of agonists of the ghrelin receptor growth hormone secretagogue-1a is a promising approach for clinical use. Randomized and placebo-controlled studies, including large number of patients are further required." @default.
- W2055142765 created "2016-06-24" @default.
- W2055142765 creator A5010897454 @default.
- W2055142765 creator A5051303907 @default.
- W2055142765 date "2008-07-01" @default.
- W2055142765 modified "2023-09-27" @default.
- W2055142765 title "The role of ghrelin and ghrelin analogues in wasting disease" @default.
- W2055142765 cites W140925007 @default.
- W2055142765 cites W1602708995 @default.
- W2055142765 cites W1616806865 @default.
- W2055142765 cites W1637971961 @default.
- W2055142765 cites W1966149402 @default.
- W2055142765 cites W1968272322 @default.
- W2055142765 cites W1971922621 @default.
- W2055142765 cites W1973484955 @default.
- W2055142765 cites W1977461900 @default.
- W2055142765 cites W1984047320 @default.
- W2055142765 cites W1986199235 @default.
- W2055142765 cites W1990056772 @default.
- W2055142765 cites W1997031720 @default.
- W2055142765 cites W1999304828 @default.
- W2055142765 cites W2004844227 @default.
- W2055142765 cites W2006713761 @default.
- W2055142765 cites W2008924996 @default.
- W2055142765 cites W2009756862 @default.
- W2055142765 cites W2009980461 @default.
- W2055142765 cites W2011253490 @default.
- W2055142765 cites W2012455440 @default.
- W2055142765 cites W2016668782 @default.
- W2055142765 cites W2017396952 @default.
- W2055142765 cites W2021018115 @default.
- W2055142765 cites W2024779930 @default.
- W2055142765 cites W2026322415 @default.
- W2055142765 cites W2031204178 @default.
- W2055142765 cites W2035580261 @default.
- W2055142765 cites W2038894275 @default.
- W2055142765 cites W2041107250 @default.
- W2055142765 cites W2044115976 @default.
- W2055142765 cites W2049105371 @default.
- W2055142765 cites W2050197669 @default.
- W2055142765 cites W2051753034 @default.
- W2055142765 cites W2052723756 @default.
- W2055142765 cites W2054986300 @default.
- W2055142765 cites W2056635534 @default.
- W2055142765 cites W2058687767 @default.
- W2055142765 cites W2059497272 @default.
- W2055142765 cites W2059864096 @default.
- W2055142765 cites W2061465125 @default.
- W2055142765 cites W2064121845 @default.
- W2055142765 cites W2064730183 @default.
- W2055142765 cites W2067177430 @default.
- W2055142765 cites W2069231788 @default.
- W2055142765 cites W2072911841 @default.
- W2055142765 cites W2073118840 @default.
- W2055142765 cites W2073367203 @default.
- W2055142765 cites W2075985511 @default.
- W2055142765 cites W2077982572 @default.
- W2055142765 cites W2082951342 @default.
- W2055142765 cites W2083560906 @default.
- W2055142765 cites W2084834028 @default.
- W2055142765 cites W2085446059 @default.
- W2055142765 cites W2086560040 @default.
- W2055142765 cites W2089256779 @default.
- W2055142765 cites W2089662309 @default.
- W2055142765 cites W2090286106 @default.
- W2055142765 cites W2090946983 @default.
- W2055142765 cites W2094874048 @default.
- W2055142765 cites W2096558321 @default.
- W2055142765 cites W2096805784 @default.
- W2055142765 cites W2103010974 @default.
- W2055142765 cites W2104673560 @default.
- W2055142765 cites W2105392793 @default.
- W2055142765 cites W2105738438 @default.
- W2055142765 cites W2106149108 @default.
- W2055142765 cites W2108122320 @default.
- W2055142765 cites W2108615218 @default.
- W2055142765 cites W2109993485 @default.
- W2055142765 cites W2110766030 @default.
- W2055142765 cites W2111536564 @default.
- W2055142765 cites W2112202133 @default.
- W2055142765 cites W2113244359 @default.
- W2055142765 cites W2117095264 @default.
- W2055142765 cites W2121445703 @default.
- W2055142765 cites W2126724435 @default.
- W2055142765 cites W2128633866 @default.
- W2055142765 cites W2129389766 @default.
- W2055142765 cites W2130520559 @default.
- W2055142765 cites W2131979270 @default.
- W2055142765 cites W2132548798 @default.
- W2055142765 cites W2132748505 @default.
- W2055142765 cites W2132828908 @default.
- W2055142765 cites W2134456501 @default.
- W2055142765 cites W2139237981 @default.
- W2055142765 cites W2140729765 @default.
- W2055142765 cites W2141793702 @default.
- W2055142765 cites W2144575734 @default.
- W2055142765 cites W2144648093 @default.
- W2055142765 cites W2146099611 @default.