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• W2055143914 abstract "The treatment of enterococcal bacteraemia is difficult due to the limited number of effective antimicrobials. All enterococci have relative resistance to β-lactam antibiotics, with rates in Enterococcus faecium approaching 90%. 1 Reynolds R. Potz N. Colman M. et al. Antimicrobial susceptibility of the pathogens of bacteraemia in the UK and Ireland 2001—2002: the BSAC bacteraemia resistance surveillance programme. J Antimicrob Chemother. 2004; 53: 1018-1032 Crossref PubMed Scopus (137) Google Scholar The emergence of vancomycin resistance from the vanA, vanB or vanC genes in the late 1980s has further complicated the picture. According to UK and Centers for Disease Control and Prevention surveillance data, 20–52% of E. faecium isolates are vancomycin resistant, compared with 2–3% of E. faecalis.1 Reynolds R. Potz N. Colman M. et al. Antimicrobial susceptibility of the pathogens of bacteraemia in the UK and Ireland 2001—2002: the BSAC bacteraemia resistance surveillance programme. J Antimicrob Chemother. 2004; 53: 1018-1032 Crossref PubMed Scopus (137) Google Scholar , 2 Multnick A.H. Enne V. Jones R.N. Linezolid resistance since 2001: SENTRY Antimicrobial Surveillance Program. Ann Pharmacother. 2003; 37: 769-773 Crossref PubMed Scopus (131) Google Scholar Linezolid, an oxazolidinone, has become an effective treatment for vancomycin-resistant enterococcus (VRE) infections. Although there have been reports of linezolid-resistant E. faecium (LREF) bacteraemias, 2 Multnick A.H. Enne V. Jones R.N. Linezolid resistance since 2001: SENTRY Antimicrobial Surveillance Program. Ann Pharmacother. 2003; 37: 769-773 Crossref PubMed Scopus (131) Google Scholar , 3 Johnson A.P. Tysall L. Stockdale M.V. et al. Emerging linezolid-resistant Enterococcus faecalis and Enterococcus faecium isolated from two Austrian patients in the same intensive care unit. Eur J Clin Microbiol Infect Dis. 2002; 21: 751-754 Crossref PubMed Scopus (112) Google Scholar , 4 Halle E. Padberg J. Rosseau S. et al. Linezolid-resistant Enterococcus faecium and Enterococcus faecalis isolated from a septic patient: report of first isolates in Germany. Infection. 2004; 32: 182-183 Crossref PubMed Scopus (26) Google Scholar we describe a case of linezolid-resistant E. faecalis bacteraemia in a neutropenic patient." @default.
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• W2055143914 date "2006-01-01" @default.
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• W2055143914 title "Emergence of linezolid-resistant enterococci in a neutropenic patient" @default.
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• W2055143914 doi "https://doi.org/10.1016/j.jhin.2005.05.008" @default.
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