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• W2055145020 endingPage "2963" @default.
• W2055145020 startingPage "2953" @default.
• W2055145020 abstract "The bacteriophage λ gene product is one of the first genes expressed during phage development. N protein allows the expression of other phage genes by altering the transcription elongation process so as to prevent transcription termination. We have found that N levels may be modulated soon after induction or infection. Using N-lacZ fusions, we determined that cells containing RNaselll have at least a fourfold greater expression than cells defective for RNaselll. This effect is exerted at the post-transcriptional level. RNaselll processes an RNA stem structure in the N- leader RNA. Removal of the stem structure by deletion increases λ expression and prevents further stimulation by RNaselll. The base of this stable stem is adjacent to the λ ribosome binding site. We present a model for control of N synthesis in which this stable stem inhibits ribosome access to the N mRNA." @default.
• W2055145020 created "2016-06-24" @default.
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• W2055145020 date "1991-12-01" @default.
• W2055145020 modified "2023-09-26" @default.
• W2055145020 title "RNaselll activation of bacteriophage ? N synthesis" @default.
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• W2055145020 doi "https://doi.org/10.1111/j.1365-2958.1991.tb01855.x" @default.
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