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- W2055149660 abstract "This study examined the effect of environmental enrichment on sucrose seeking in rats made abstinent from sucrose for 1 month, as measured by response for a tone+light cue previously associated with 10% sucrose self-administration. Rats were either enriched throughout the study (experiment 1) or only after sucrose self-administration training (experiment 2). Enrichment consisted of either housing the rats in pairs or grouping four rats (ENR4) in a large environment, both with novel objects. Controls (CON) were singly housed without novel objects. In experiment 1, ENR4 rats responded less to the sucrose-paired cue versus CON rats, but this difference was not statistically significant. In contrast, the decrease in response of ENR4 rats versus CON rats in experiment 2 was dramatic and significant. These findings, along with findings from other laboratories, support a hypothesis that the enrichment may provide individuals with a greater ability to discriminate the availability of reward. This may impart a decreased vulnerability to relapse behavior. Therefore, these results are relevant to both eating disorder and drug addiction - disorders characterized by relapse." @default.
- W2055149660 created "2016-06-24" @default.
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- W2055149660 date "2008-12-01" @default.
- W2055149660 modified "2023-10-18" @default.
- W2055149660 title "Environmental enrichment attenuates cue-induced reinstatement of sucrose seeking in rats" @default.
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- W2055149660 doi "https://doi.org/10.1097/fbp.0b013e32831c3b18" @default.
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