FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055172046> ?p ?o ?g. }

• W2055172046 endingPage "757" @default.
• W2055172046 startingPage "736" @default.
• W2055172046 abstract "ABSTRACT The unicellular green alga Chlamydomonas reinhardtii is a valuable model for studying metal metabolism in a photosynthetic background. A search of the Chlamydomonas expressed sequence tag database led to the identification of several components that form a copper-dependent iron assimilation pathway related to the high-affinity iron uptake pathway defined originally for Saccharomyces cerevisiae . They include a multicopper ferroxidase (encoded by Fox1 ), an iron permease (encoded by Ftr1 ), a copper chaperone (encoded by Atx1 ), and a copper-transporting ATPase. A cDNA, Fer1 , encoding ferritin for iron storage also was identified. Expression analysis demonstrated that Fox1 and Ftr1 were coordinately induced by iron deficiency, as were Atx1 and Fer1 , although to lesser extents. In addition, Fox1 abundance was regulated at the posttranscriptional level by copper availability. Each component exhibited sequence relationship with its yeast, mammalian, or plant counterparts to various degrees; Atx1 of C. reinhardtii is also functionally related with respect to copper chaperone and antioxidant activities. Fox1 is most highly related to the mammalian homologues hephaestin and ceruloplasmin; its occurrence and pattern of expression in Chlamydomonas indicate, for the first time, a role for copper in iron assimilation in a photosynthetic species. Nevertheless, growth of C. reinhardtii under copper- and iron-limiting conditions showed that, unlike the situation in yeast and mammals, where copper deficiency results in a secondary iron deficiency, copper-deficient Chlamydomonas cells do not exhibit symptoms of iron deficiency. We propose the existence of a copper-independent iron assimilation pathway in this organism." @default.
• W2055172046 created "2016-06-24" @default.
• W2055172046 creator A5020668995 @default.
• W2055172046 creator A5027379612 @default.
• W2055172046 creator A5051108430 @default.
• W2055172046 creator A5052051439 @default.
• W2055172046 creator A5054892819 @default.
• W2055172046 creator A5065501629 @default.
• W2055172046 creator A5074043407 @default.
• W2055172046 creator A5079308326 @default.
• W2055172046 date "2002-10-01" @default.
• W2055172046 modified "2023-10-03" @default.
• W2055172046 title "Copper-Dependent Iron Assimilation Pathway in the Model Photosynthetic Eukaryote <i>Chlamydomonas reinhardtii</i>" @default.
• W2055172046 cites W1493966034 @default.
• W2055172046 cites W1496352141 @default.
• W2055172046 cites W1509386929 @default.
• W2055172046 cites W1515013277 @default.
• W2055172046 cites W1523481867 @default.
• W2055172046 cites W1569266313 @default.
• W2055172046 cites W1588913699 @default.
• W2055172046 cites W1597130528 @default.
• W2055172046 cites W1597247216 @default.
• W2055172046 cites W1599093544 @default.
• W2055172046 cites W1618001767 @default.
• W2055172046 cites W1696228719 @default.
• W2055172046 cites W1735246691 @default.
• W2055172046 cites W1768592838 @default.
• W2055172046 cites W1823429334 @default.
• W2055172046 cites W1849807599 @default.
• W2055172046 cites W185785554 @default.
• W2055172046 cites W1869259273 @default.
• W2055172046 cites W1964670708 @default.
• W2055172046 cites W1965202020 @default.
• W2055172046 cites W1967941369 @default.
• W2055172046 cites W1968898079 @default.
• W2055172046 cites W1969060808 @default.
• W2055172046 cites W1972487430 @default.
• W2055172046 cites W1975304761 @default.
• W2055172046 cites W1977426810 @default.
• W2055172046 cites W1992630550 @default.
• W2055172046 cites W1995197829 @default.
• W2055172046 cites W1995770341 @default.
• W2055172046 cites W1999406116 @default.
• W2055172046 cites W2003755785 @default.
• W2055172046 cites W2005806732 @default.
• W2055172046 cites W2008778493 @default.
• W2055172046 cites W2011444292 @default.
• W2055172046 cites W2011963881 @default.
• W2055172046 cites W2016067359 @default.
• W2055172046 cites W2017861724 @default.
• W2055172046 cites W2019914595 @default.
• W2055172046 cites W2027337223 @default.
• W2055172046 cites W202855222 @default.
• W2055172046 cites W2035347343 @default.
• W2055172046 cites W2038766809 @default.
• W2055172046 cites W2039192785 @default.
• W2055172046 cites W2042904461 @default.
• W2055172046 cites W2047523779 @default.
• W2055172046 cites W2048124973 @default.
• W2055172046 cites W2049604444 @default.
• W2055172046 cites W2049849193 @default.
• W2055172046 cites W2054708511 @default.
• W2055172046 cites W2055432880 @default.
• W2055172046 cites W2058861773 @default.
• W2055172046 cites W2059737016 @default.
• W2055172046 cites W2061040884 @default.
• W2055172046 cites W2061827122 @default.
• W2055172046 cites W2063325494 @default.
• W2055172046 cites W2063617352 @default.
• W2055172046 cites W2064330033 @default.
• W2055172046 cites W2064433731 @default.
• W2055172046 cites W2066456671 @default.
• W2055172046 cites W2069044991 @default.
• W2055172046 cites W2073195145 @default.
• W2055172046 cites W2075210340 @default.
• W2055172046 cites W2075233489 @default.
• W2055172046 cites W2085955757 @default.
• W2055172046 cites W2087276505 @default.
• W2055172046 cites W2088152932 @default.
• W2055172046 cites W2091688888 @default.
• W2055172046 cites W2093503663 @default.
• W2055172046 cites W2095238965 @default.
• W2055172046 cites W2096266908 @default.
• W2055172046 cites W2096976702 @default.
• W2055172046 cites W2098772551 @default.
• W2055172046 cites W2105749655 @default.
• W2055172046 cites W2106442871 @default.
• W2055172046 cites W2108556965 @default.
• W2055172046 cites W2113131102 @default.
• W2055172046 cites W2116368658 @default.
• W2055172046 cites W2118664522 @default.
• W2055172046 cites W2120684043 @default.
• W2055172046 cites W2120811498 @default.
• W2055172046 cites W2122065944 @default.
• W2055172046 cites W2122351685 @default.
• W2055172046 cites W2123319557 @default.
• W2055172046 cites W2129951991 @default.
• W2055172046 cites W2132863560 @default.

• next