Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055175035> ?p ?o ?g. }
- W2055175035 endingPage "1200" @default.
- W2055175035 startingPage "1194" @default.
- W2055175035 abstract "The CD36 molecule is expressed in platelets, monocytes, erythroblasts, and other different tissues. The two types of platelet CD36 deficiency, types I and II, are associated with the absence and presence of CD36 on monocytes, respectively. To clarify the involvement of the erythroid lineage in CD36 deficiency, we investigated the phenotype and RNA expression of CD36.CD36 expression was examined in 296 patients with several cardiovascular diseases in our outpatient clinic. There were 12 patients with type I deficiency and 16 with type II CD36 deficiency. A bone marrow sample was examined in five type I and four type II patients. Expression of CD36 mRNA was examined in burst-forming unit-erythroid (BFU-E). The sequences of reverse transcriptase polymerase chain reaction (RT-PCR) products of the CD36 mRNA from monocytes were examined.As expected, CD36 was deficient in erythroblasts from all five patients with type I deficiency. CD36 was present in erythroblasts from three of the four with type II deficiency, suggesting that their abnormality is restricted to platelets (type IIa). CD36 was unexpectedly absent from erythroblasts of a single type II patient (type IIb). CD36-specific mRNA was identified in BFU-E from each of two normals, six type I, and six type II patients, including type IIb. The sequences of RT-PCR products of the CD36 mRNA in a patient with type IIa and another with type IIb showed homozygous wild alleles.The findings provide evidence for further heterogeneity among CD36-deficient individuals and the existence of a basic principle mechanism of type II, such as glycosylation abnormality." @default.
- W2055175035 created "2016-06-24" @default.
- W2055175035 creator A5010920203 @default.
- W2055175035 creator A5036433330 @default.
- W2055175035 creator A5047353543 @default.
- W2055175035 creator A5055227838 @default.
- W2055175035 creator A5068336316 @default.
- W2055175035 creator A5068445895 @default.
- W2055175035 creator A5068564727 @default.
- W2055175035 creator A5083034275 @default.
- W2055175035 creator A5085030384 @default.
- W2055175035 creator A5089924378 @default.
- W2055175035 date "2001-10-01" @default.
- W2055175035 modified "2023-10-18" @default.
- W2055175035 title "Erythroid involvement in CD36 deficiency" @default.
- W2055175035 cites W1486291800 @default.
- W2055175035 cites W1512516272 @default.
- W2055175035 cites W1513904594 @default.
- W2055175035 cites W1519054456 @default.
- W2055175035 cites W1562774051 @default.
- W2055175035 cites W1653408396 @default.
- W2055175035 cites W190906149 @default.
- W2055175035 cites W1927046050 @default.
- W2055175035 cites W1973644618 @default.
- W2055175035 cites W1977049843 @default.
- W2055175035 cites W1997481583 @default.
- W2055175035 cites W2001266107 @default.
- W2055175035 cites W2005818682 @default.
- W2055175035 cites W2006285358 @default.
- W2055175035 cites W2022699338 @default.
- W2055175035 cites W2024131238 @default.
- W2055175035 cites W2040049631 @default.
- W2055175035 cites W2043748949 @default.
- W2055175035 cites W2046121370 @default.
- W2055175035 cites W2049409827 @default.
- W2055175035 cites W2054323447 @default.
- W2055175035 cites W2055515174 @default.
- W2055175035 cites W2065766518 @default.
- W2055175035 cites W2073771773 @default.
- W2055175035 cites W2075435350 @default.
- W2055175035 cites W2078091763 @default.
- W2055175035 cites W2085541452 @default.
- W2055175035 cites W2091708390 @default.
- W2055175035 cites W2093782393 @default.
- W2055175035 cites W2094431012 @default.
- W2055175035 cites W2094912454 @default.
- W2055175035 cites W2095365626 @default.
- W2055175035 cites W2113682801 @default.
- W2055175035 cites W2148582447 @default.
- W2055175035 cites W2159316425 @default.
- W2055175035 cites W2372551532 @default.
- W2055175035 cites W2396077035 @default.
- W2055175035 cites W2406080504 @default.
- W2055175035 cites W2409511550 @default.
- W2055175035 cites W4234167212 @default.
- W2055175035 cites W4252115312 @default.
- W2055175035 cites W4256265928 @default.
- W2055175035 doi "https://doi.org/10.1016/s0301-472x(01)00691-9" @default.
- W2055175035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11602321" @default.
- W2055175035 hasPublicationYear "2001" @default.
- W2055175035 type Work @default.
- W2055175035 sameAs 2055175035 @default.
- W2055175035 citedByCount "8" @default.
- W2055175035 countsByYear W20551750352015 @default.
- W2055175035 countsByYear W20551750352016 @default.
- W2055175035 crossrefType "journal-article" @default.
- W2055175035 hasAuthorship W2055175035A5010920203 @default.
- W2055175035 hasAuthorship W2055175035A5036433330 @default.
- W2055175035 hasAuthorship W2055175035A5047353543 @default.
- W2055175035 hasAuthorship W2055175035A5055227838 @default.
- W2055175035 hasAuthorship W2055175035A5068336316 @default.
- W2055175035 hasAuthorship W2055175035A5068445895 @default.
- W2055175035 hasAuthorship W2055175035A5068564727 @default.
- W2055175035 hasAuthorship W2055175035A5083034275 @default.
- W2055175035 hasAuthorship W2055175035A5085030384 @default.
- W2055175035 hasAuthorship W2055175035A5089924378 @default.
- W2055175035 hasBestOaLocation W20551750351 @default.
- W2055175035 hasConcept C104317684 @default.
- W2055175035 hasConcept C105580179 @default.
- W2055175035 hasConcept C153911025 @default.
- W2055175035 hasConcept C203014093 @default.
- W2055175035 hasConcept C2779828298 @default.
- W2055175035 hasConcept C54355233 @default.
- W2055175035 hasConcept C71924100 @default.
- W2055175035 hasConcept C86803240 @default.
- W2055175035 hasConcept C89560881 @default.
- W2055175035 hasConceptScore W2055175035C104317684 @default.
- W2055175035 hasConceptScore W2055175035C105580179 @default.
- W2055175035 hasConceptScore W2055175035C153911025 @default.
- W2055175035 hasConceptScore W2055175035C203014093 @default.
- W2055175035 hasConceptScore W2055175035C2779828298 @default.
- W2055175035 hasConceptScore W2055175035C54355233 @default.
- W2055175035 hasConceptScore W2055175035C71924100 @default.
- W2055175035 hasConceptScore W2055175035C86803240 @default.
- W2055175035 hasConceptScore W2055175035C89560881 @default.
- W2055175035 hasIssue "10" @default.
- W2055175035 hasLocation W20551750351 @default.
- W2055175035 hasLocation W20551750352 @default.