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- W2055197150 abstract "Methods for calculating maximum residue levels or, at least, high percentile values (e.g. 95th percentile) to support the estimation have been developed in recent years. A mathematical equation is proposed that, for a set of supervised pesticide residue trials on a crop, expresses the incidence of residues as a function of residue concentration in the food commodity. Each residue concentration is expressed as a population reflecting its intra-trial variability. The equation is then the sum of these sub-populations to represent the set of trials, a population of sub-populations (POSP). The equation is formulated so that the area under the curve precisely equals the number of trials. Calculation of a residue concentration corresponding to a percentage of the area under the curve produces the required percentile. Results are generally consistent with the current OECD method calculation. The POSP calculation will be a useful tool in estimating maximum residue levels, where the first choice, other matters being acceptable, would be a value between the 95th and 99th percentiles. Replicate data are directly accommodated in the calculation. The POSP calculator can answer such questions as: what percentile corresponds to the highest residue (HR) in the residue data set?" @default.
- W2055197150 created "2016-06-24" @default.
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- W2055197150 date "2015-06-01" @default.
- W2055197150 modified "2023-09-27" @default.
- W2055197150 title "MRL calculations based on both intra- and inter-trial residue variability" @default.
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- W2055197150 doi "https://doi.org/10.1016/j.yrtph.2015.03.002" @default.
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