Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055200701> ?p ?o ?g. }
- W2055200701 endingPage "405" @default.
- W2055200701 startingPage "399" @default.
- W2055200701 abstract "Distinct patterns of [3H]nicotine (3 nm) binding were apparent in various regions of adult human neo- and archicortex. Receptor binding was greatest in the subicular complex—particularly presubiculum—and entorhinal cortex, where it was prominent in the characteristic parvo- and magnocellular islands of these regions and in middle layers of entorhinal cortex. In somatosensory cortex (Brodmann areas 3, 1 and 2) and occipital (area 17) cortex binding was highest in the upper and lower layers, and relatively sparse in the sensory input, layer IV. In primary motor (area 4) and temporal (area 21) cortex, binding in the outer half of the cortical ribbon was denser than that in the inner half and a distinct band was apparent in temporal and cingulate (area 32) in the lower portion of layer III. In prefrontal association cortex the pattern of binding was less distinct although slightly higher in the lower architectonic layers. There was generally little binding in the hippocampus (areas CA1–4) and dentate gyrus with the exception of the stratum lacunosum moleculare in CA2–3 and, to a lesser extent, supra- and subgranule zones of the dentate. These patterns of reactivity, which are distinct from that of the major cortical cholinergic innervation, suggest that the nicotinic receptor, detected using nanomolar concentrations of [3H]nicotine, may primarily be associated with intracortical circuitry in the neocortex. The relatively high density in entorhinal and subicular regions may be related to the extensive phylogenetic development of these regions which has occurred in conjunction with the development of multimodal association circuitry in the human cortex." @default.
- W2055200701 created "2016-06-24" @default.
- W2055200701 creator A5001741634 @default.
- W2055200701 creator A5008386494 @default.
- W2055200701 creator A5028055336 @default.
- W2055200701 creator A5054997532 @default.
- W2055200701 creator A5091136172 @default.
- W2055200701 date "1992-09-01" @default.
- W2055200701 modified "2023-09-25" @default.
- W2055200701 title "Autoradiographic distribution of [3H]nicotine binding in human cortex: Relative abundance in subicular complex" @default.
- W2055200701 cites W1760834562 @default.
- W2055200701 cites W1964178477 @default.
- W2055200701 cites W1970995389 @default.
- W2055200701 cites W1973400059 @default.
- W2055200701 cites W1973406239 @default.
- W2055200701 cites W1984115988 @default.
- W2055200701 cites W1986661319 @default.
- W2055200701 cites W2015949771 @default.
- W2055200701 cites W2022212313 @default.
- W2055200701 cites W2027799011 @default.
- W2055200701 cites W2038995429 @default.
- W2055200701 cites W2041312279 @default.
- W2055200701 cites W2042661837 @default.
- W2055200701 cites W2043419693 @default.
- W2055200701 cites W2051119534 @default.
- W2055200701 cites W2051343857 @default.
- W2055200701 cites W2053109154 @default.
- W2055200701 cites W2053656727 @default.
- W2055200701 cites W2063084145 @default.
- W2055200701 cites W2064409479 @default.
- W2055200701 cites W2069317157 @default.
- W2055200701 cites W2091054587 @default.
- W2055200701 cites W2097326214 @default.
- W2055200701 cites W2097340892 @default.
- W2055200701 cites W2146073951 @default.
- W2055200701 cites W2303390475 @default.
- W2055200701 cites W2417351272 @default.
- W2055200701 doi "https://doi.org/10.1016/0891-0618(92)90056-v" @default.
- W2055200701 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1418753" @default.
- W2055200701 hasPublicationYear "1992" @default.
- W2055200701 type Work @default.
- W2055200701 sameAs 2055200701 @default.
- W2055200701 citedByCount "45" @default.
- W2055200701 countsByYear W20552007012014 @default.
- W2055200701 countsByYear W20552007012015 @default.
- W2055200701 countsByYear W20552007012016 @default.
- W2055200701 countsByYear W20552007012017 @default.
- W2055200701 countsByYear W20552007012018 @default.
- W2055200701 countsByYear W20552007012019 @default.
- W2055200701 countsByYear W20552007012020 @default.
- W2055200701 countsByYear W20552007012021 @default.
- W2055200701 crossrefType "journal-article" @default.
- W2055200701 hasAuthorship W2055200701A5001741634 @default.
- W2055200701 hasAuthorship W2055200701A5008386494 @default.
- W2055200701 hasAuthorship W2055200701A5028055336 @default.
- W2055200701 hasAuthorship W2055200701A5054997532 @default.
- W2055200701 hasAuthorship W2055200701A5091136172 @default.
- W2055200701 hasConcept C105702510 @default.
- W2055200701 hasConcept C148762608 @default.
- W2055200701 hasConcept C169760540 @default.
- W2055200701 hasConcept C185592680 @default.
- W2055200701 hasConcept C2776464000 @default.
- W2055200701 hasConcept C2777222312 @default.
- W2055200701 hasConcept C2777348757 @default.
- W2055200701 hasConcept C2778499278 @default.
- W2055200701 hasConcept C2780715579 @default.
- W2055200701 hasConcept C2781161787 @default.
- W2055200701 hasConcept C2993858690 @default.
- W2055200701 hasConcept C86803240 @default.
- W2055200701 hasConceptScore W2055200701C105702510 @default.
- W2055200701 hasConceptScore W2055200701C148762608 @default.
- W2055200701 hasConceptScore W2055200701C169760540 @default.
- W2055200701 hasConceptScore W2055200701C185592680 @default.
- W2055200701 hasConceptScore W2055200701C2776464000 @default.
- W2055200701 hasConceptScore W2055200701C2777222312 @default.
- W2055200701 hasConceptScore W2055200701C2777348757 @default.
- W2055200701 hasConceptScore W2055200701C2778499278 @default.
- W2055200701 hasConceptScore W2055200701C2780715579 @default.
- W2055200701 hasConceptScore W2055200701C2781161787 @default.
- W2055200701 hasConceptScore W2055200701C2993858690 @default.
- W2055200701 hasConceptScore W2055200701C86803240 @default.
- W2055200701 hasIssue "5" @default.
- W2055200701 hasLocation W20552007011 @default.
- W2055200701 hasLocation W20552007012 @default.
- W2055200701 hasOpenAccess W2055200701 @default.
- W2055200701 hasPrimaryLocation W20552007011 @default.
- W2055200701 hasRelatedWork W1769572743 @default.
- W2055200701 hasRelatedWork W2040613425 @default.
- W2055200701 hasRelatedWork W2056718498 @default.
- W2055200701 hasRelatedWork W2076167286 @default.
- W2055200701 hasRelatedWork W2082455255 @default.
- W2055200701 hasRelatedWork W2110836796 @default.
- W2055200701 hasRelatedWork W2113942169 @default.
- W2055200701 hasRelatedWork W2468581135 @default.
- W2055200701 hasRelatedWork W2904695463 @default.
- W2055200701 hasRelatedWork W3086948554 @default.
- W2055200701 hasVolume "5" @default.
- W2055200701 isParatext "false" @default.