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- W2055205669 abstract "Abstract Erythrocytes in blood from sickle cell anemia patients become less flexible as the oxygen tension in the blood decreases. The present work is concerned with the development of a method of predicting the resulting resistance to flow as a function of oxygen tension. Oxygen consumption in the capillaries is accounted for through the “Krogh cylinder model,” while lubrication theory is used to determine the resistance to flow. These two models are coupled by an experimentally determined relationship between erythrocyte flexibility and oxygen tension. Predicted levels of resistance are up to 8 times greater than those obtained without taking oxygen consumption into account." @default.
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- W2055205669 date "1977-01-01" @default.
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- W2055205669 title "A mathematical model of the effect of oxygen consumption on the resistance to flow of sickle cell blood in capillaries" @default.
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- W2055205669 doi "https://doi.org/10.1016/0025-5564(77)90078-5" @default.
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