FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055220141> ?p ?o ?g. }

• W2055220141 endingPage "12" @default.
• W2055220141 startingPage "3" @default.
• W2055220141 abstract "Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been explored widely for DNA sequencing. Compared to gel electrophoresis based sequencing systems, mass spectrometry produces very high resolution of sequencing fragments, rapid separation on microsecond time scales, and completely eliminates compressions associated with gel-based systems. While most of the research efforts have focused on using mass spectrometers to analyze the DNA products from Sanger sequencing or enzymatic digestion reactions, the read lengths attainable are currently insufficient for large-scale de novo sequencing. The advantage of mass-spectrometry sequencing is that one can unambiguously identify frameshift mutations and heterozygous mutations making it an ideal choice for resequencing projects. In these applications, DNA sequencing fragments that are the same length but with different base compositions are generated, which are challenging to consistently distinguish in gel-based sequencing systems. In contrast, MALDI-TOF MS produces mass spectra of these DNA sequencing fragments with nearly digital resolution, allowing accurate determination of the mixed bases. For these reasons mass spectrometry based sequencing has mainly been focused on the detection of frameshift mutations and single nucleotide polymorphisms (SNPs). More recently, assays have been developed to indirectly sequence DNA by first converting it into RNA. These assays take advantage of the increased resolution and detection ability of MALDI-TOF MS for RNA." @default.
• W2055220141 created "2016-06-24" @default.
• W2055220141 creator A5031877880 @default.
• W2055220141 creator A5041587384 @default.
• W2055220141 creator A5084552494 @default.
• W2055220141 date "2005-06-01" @default.
• W2055220141 modified "2023-10-10" @default.
• W2055220141 title "Mass-spectrometry DNA sequencing" @default.
• W2055220141 cites W1548317396 @default.
• W2055220141 cites W1658221551 @default.
• W2055220141 cites W1964686190 @default.
• W2055220141 cites W1969757078 @default.
• W2055220141 cites W1972211922 @default.
• W2055220141 cites W1977298700 @default.
• W2055220141 cites W1978349009 @default.
• W2055220141 cites W1983939557 @default.
• W2055220141 cites W1987146517 @default.
• W2055220141 cites W1988659744 @default.
• W2055220141 cites W1996415245 @default.
• W2055220141 cites W2000150613 @default.
• W2055220141 cites W2004935367 @default.
• W2055220141 cites W2021790416 @default.
• W2055220141 cites W2023963622 @default.
• W2055220141 cites W2025888918 @default.
• W2055220141 cites W2028989854 @default.
• W2055220141 cites W2034588913 @default.
• W2055220141 cites W2035058958 @default.
• W2055220141 cites W2047940872 @default.
• W2055220141 cites W2062723602 @default.
• W2055220141 cites W2072303358 @default.
• W2055220141 cites W2073292063 @default.
• W2055220141 cites W2089166604 @default.
• W2055220141 cites W2097485866 @default.
• W2055220141 cites W2105254473 @default.
• W2055220141 cites W2127230663 @default.
• W2055220141 cites W2129425318 @default.
• W2055220141 cites W2129505803 @default.
• W2055220141 cites W2129937879 @default.
• W2055220141 cites W2138270253 @default.
• W2055220141 cites W2138706632 @default.
• W2055220141 cites W2145839720 @default.
• W2055220141 cites W2149929487 @default.
• W2055220141 cites W2151492295 @default.
• W2055220141 cites W2159351303 @default.
• W2055220141 cites W2168909179 @default.
• W2055220141 doi "https://doi.org/10.1016/j.mrfmmm.2004.07.021" @default.
• W2055220141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15829234" @default.
• W2055220141 hasPublicationYear "2005" @default.
• W2055220141 type Work @default.
• W2055220141 sameAs 2055220141 @default.
• W2055220141 citedByCount "68" @default.
• W2055220141 countsByYear W20552201412012 @default.
• W2055220141 countsByYear W20552201412013 @default.
• W2055220141 countsByYear W20552201412014 @default.
• W2055220141 countsByYear W20552201412015 @default.
• W2055220141 countsByYear W20552201412016 @default.
• W2055220141 countsByYear W20552201412017 @default.
• W2055220141 countsByYear W20552201412018 @default.
• W2055220141 countsByYear W20552201412019 @default.
• W2055220141 countsByYear W20552201412020 @default.
• W2055220141 countsByYear W20552201412021 @default.
• W2055220141 countsByYear W20552201412022 @default.
• W2055220141 countsByYear W20552201412023 @default.
• W2055220141 crossrefType "journal-article" @default.
• W2055220141 hasAuthorship W2055220141A5031877880 @default.
• W2055220141 hasAuthorship W2055220141A5041587384 @default.
• W2055220141 hasAuthorship W2055220141A5084552494 @default.
• W2055220141 hasConcept C104317684 @default.
• W2055220141 hasConcept C162356407 @default.
• W2055220141 hasConcept C185592680 @default.
• W2055220141 hasConcept C192800701 @default.
• W2055220141 hasConcept C29906990 @default.
• W2055220141 hasConcept C43617362 @default.
• W2055220141 hasConcept C501734568 @default.
• W2055220141 hasConcept C51679486 @default.
• W2055220141 hasConcept C54355233 @default.
• W2055220141 hasConcept C552990157 @default.
• W2055220141 hasConcept C70712619 @default.
• W2055220141 hasConcept C70721500 @default.
• W2055220141 hasConcept C76818968 @default.
• W2055220141 hasConcept C86803240 @default.
• W2055220141 hasConceptScore W2055220141C104317684 @default.
• W2055220141 hasConceptScore W2055220141C162356407 @default.
• W2055220141 hasConceptScore W2055220141C185592680 @default.
• W2055220141 hasConceptScore W2055220141C192800701 @default.
• W2055220141 hasConceptScore W2055220141C29906990 @default.
• W2055220141 hasConceptScore W2055220141C43617362 @default.
• W2055220141 hasConceptScore W2055220141C501734568 @default.
• W2055220141 hasConceptScore W2055220141C51679486 @default.
• W2055220141 hasConceptScore W2055220141C54355233 @default.
• W2055220141 hasConceptScore W2055220141C552990157 @default.
• W2055220141 hasConceptScore W2055220141C70712619 @default.
• W2055220141 hasConceptScore W2055220141C70721500 @default.
• W2055220141 hasConceptScore W2055220141C76818968 @default.
• W2055220141 hasConceptScore W2055220141C86803240 @default.
• W2055220141 hasIssue "1-2" @default.
• W2055220141 hasLocation W20552201411 @default.
• W2055220141 hasLocation W20552201412 @default.

• next