FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055238335> ?p ?o ?g. }

• W2055238335 endingPage "143" @default.
• W2055238335 startingPage "135" @default.
• W2055238335 abstract "Objective: We investigated the effects of thyroxine (T4) therapy on the cardiac function in subclinical hypothyroidism (SHT) by using the index of myocardial performance (IMP) and the conventional echocardiographic parameters. Methods: Forty-five SHT patients (F/M:38/7, age 39.9±7.9) and 29 healthy subjects (F/M:25/4, age 38.3±8.6) were studied. Patients were randomly assigned, in a double-blind manner to receive T4 therapy (group I) or a placebo (group II) and for a period of up to 12 months, were followed up using thyroid function tests and both conventional and Doppler echocardiographic measurements. Results: At the baseline, the SHT patients has a significantly higher isovolumic relaxation time (IRT) (98.3±23.7 vs. 81.7±14.7<0.01), IMP (0.52±0.06 vs. 0.42±0.05; P<0.001), A max (late mitral peak velocity) (83.4±12.6 vs. 74.3±13.5; P<0.01) and significantly lower (early mitral peak velocity) Emax/Amax ratio (1.19±0.18 vs. 1.34±0.17; P<0.01) than the individuals in the control group. In group I, the thyroid hormone profile became normalized after 1 year of L-T4 therapy, but there was no significant change in the left ventricular (LV) morphology or systolic function. After 1 year of follow-up, group I showed a significant reduction of MPI (0.53±0.05 vs. 0.42±0.07; P<0.001), Amax (84.2±13.7 vs. 74.5±11; P<0.001) and IRT (98.6±23.7 vs. 82.9± 23.3; P<0.001) along with a normalization of the E/A ratio (1.17±0.16 vs. 1.33±0.19; P<0.001). Conversely, no change was observed in group II. Conclusions: An impairment of left ventricular diastolic function, which may be reversible with T4 therapy, was observed in the SHT patients, and IMP may be useful in the evaluation of LV myocardial dysfunction in these patients." @default.
• W2055238335 created "2016-06-24" @default.
• W2055238335 creator A5013834457 @default.
• W2055238335 creator A5060907347 @default.
• W2055238335 creator A5064155652 @default.
• W2055238335 creator A5066763910 @default.
• W2055238335 creator A5076837028 @default.
• W2055238335 creator A5084703761 @default.
• W2055238335 creator A5085366042 @default.
• W2055238335 date "2004-06-01" @default.
• W2055238335 modified "2023-10-17" @default.
• W2055238335 title "Effects of thyroxin therapy on cardiac function in patients with subclinical hypothyroidism: index of myocardial performance in the evaluation of left ventricular function" @default.
• W2055238335 cites W1597094273 @default.
• W2055238335 cites W1968007805 @default.
• W2055238335 cites W1970709107 @default.
• W2055238335 cites W1971576580 @default.
• W2055238335 cites W1971963079 @default.
• W2055238335 cites W1976274614 @default.
• W2055238335 cites W1989945628 @default.
• W2055238335 cites W1995934832 @default.
• W2055238335 cites W2001674341 @default.
• W2055238335 cites W2005815716 @default.
• W2055238335 cites W2006323076 @default.
• W2055238335 cites W2011275871 @default.
• W2055238335 cites W2011659584 @default.
• W2055238335 cites W2014395731 @default.
• W2055238335 cites W2015240109 @default.
• W2055238335 cites W2025361248 @default.
• W2055238335 cites W2028785373 @default.
• W2055238335 cites W2034922137 @default.
• W2055238335 cites W2042315468 @default.
• W2055238335 cites W2054338703 @default.
• W2055238335 cites W2069934475 @default.
• W2055238335 cites W2073409711 @default.
• W2055238335 cites W2077688299 @default.
• W2055238335 cites W2078996989 @default.
• W2055238335 cites W2090982939 @default.
• W2055238335 cites W2093501112 @default.
• W2055238335 cites W2115439326 @default.
• W2055238335 cites W2116564435 @default.
• W2055238335 cites W2126011638 @default.
• W2055238335 cites W2140936682 @default.
• W2055238335 cites W2145875716 @default.
• W2055238335 cites W2148113299 @default.
• W2055238335 cites W2175579169 @default.
• W2055238335 cites W2783184124 @default.
• W2055238335 cites W4205751543 @default.
• W2055238335 cites W4229541493 @default.
• W2055238335 cites W4239531548 @default.
• W2055238335 cites W4241270956 @default.
• W2055238335 cites W4246488809 @default.
• W2055238335 cites W4294294150 @default.
• W2055238335 cites W4321509058 @default.
• W2055238335 doi "https://doi.org/10.1016/j.ijcard.2003.05.015" @default.
• W2055238335 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15193811" @default.
• W2055238335 hasPublicationYear "2004" @default.
• W2055238335 type Work @default.
• W2055238335 sameAs 2055238335 @default.
• W2055238335 citedByCount "88" @default.
• W2055238335 countsByYear W20552383352012 @default.
• W2055238335 countsByYear W20552383352013 @default.
• W2055238335 countsByYear W20552383352014 @default.
• W2055238335 countsByYear W20552383352015 @default.
• W2055238335 countsByYear W20552383352016 @default.
• W2055238335 countsByYear W20552383352017 @default.
• W2055238335 countsByYear W20552383352018 @default.
• W2055238335 countsByYear W20552383352019 @default.
• W2055238335 countsByYear W20552383352020 @default.
• W2055238335 countsByYear W20552383352021 @default.
• W2055238335 countsByYear W20552383352023 @default.
• W2055238335 crossrefType "journal-article" @default.
• W2055238335 hasAuthorship W2055238335A5013834457 @default.
• W2055238335 hasAuthorship W2055238335A5060907347 @default.
• W2055238335 hasAuthorship W2055238335A5064155652 @default.
• W2055238335 hasAuthorship W2055238335A5066763910 @default.
• W2055238335 hasAuthorship W2055238335A5076837028 @default.
• W2055238335 hasAuthorship W2055238335A5084703761 @default.
• W2055238335 hasAuthorship W2055238335A5085366042 @default.
• W2055238335 hasConcept C111566952 @default.
• W2055238335 hasConcept C113280763 @default.
• W2055238335 hasConcept C126322002 @default.
• W2055238335 hasConcept C134018914 @default.
• W2055238335 hasConcept C142724271 @default.
• W2055238335 hasConcept C164705383 @default.
• W2055238335 hasConcept C204787440 @default.
• W2055238335 hasConcept C27081682 @default.
• W2055238335 hasConcept C2778198053 @default.
• W2055238335 hasConcept C2778840127 @default.
• W2055238335 hasConcept C2779868719 @default.
• W2055238335 hasConcept C2780346441 @default.
• W2055238335 hasConcept C2993291352 @default.
• W2055238335 hasConcept C2993376042 @default.
• W2055238335 hasConcept C39078644 @default.
• W2055238335 hasConcept C526584372 @default.
• W2055238335 hasConcept C57900726 @default.
• W2055238335 hasConcept C71924100 @default.
• W2055238335 hasConcept C84393581 @default.
• W2055238335 hasConceptScore W2055238335C111566952 @default.

• next