FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055246505> ?p ?o ?g. }

• W2055246505 endingPage "1105" @default.
• W2055246505 startingPage "1099" @default.
• W2055246505 abstract "Congenital dislocation of the hip (CDH), which is one of the most common congenital skeletal disorders, corresponds to an abnormal seating of the femoral head in the acetabulum. It is commonly admitted that CDH presents a genetic component. However, little is known about the genetic factors involved. This study aimed to determine the role of two potential candidate genes on chromosome 17 in CDH: HOXB9 (involved in limb embryonic development) and COL1A1 (involved in joint laxity).We set up a case-control association study (239 cases and 239 controls) in western Brittany (France) where CDH is particularly frequent. The set of informative single nucleotide polymorphisms (SNPs) in each gene was selected using Tagger and genotyped using the SNaPshot method (n=2 and n=10, respectively). The association was tested both through single-locus and haplotype-based analyses, using SAS and Haploview softwares. In addition, we carried out the transmission disequilibrium test (TDT) with the same polymorphisms from a sample of 81 trios (i.e., 81 patients included in the case-control study and their both parents).The case-control study revealed no significant association between CDH and the tagSNPs selected in both HOXB9 and COL1A1. Moreover, the TDT did not reveal distortion in allelic and haplotype transmission of the studied markers.Our study did not support an association between HOXB9 and COL1A1 and CDH in our population. These negative findings were obtained by population- and family-based designs. Analysis of the genetic component of CDH should focus on other candidate genes." @default.
• W2055246505 created "2016-06-24" @default.
• W2055246505 creator A5013374671 @default.
• W2055246505 creator A5019865477 @default.
• W2055246505 creator A5028565837 @default.
• W2055246505 creator A5034851133 @default.
• W2055246505 creator A5041403850 @default.
• W2055246505 creator A5044204023 @default.
• W2055246505 creator A5057288832 @default.
• W2055246505 creator A5066521398 @default.
• W2055246505 creator A5079912358 @default.
• W2055246505 date "2009-08-01" @default.
• W2055246505 modified "2023-10-11" @default.
• W2055246505 title "Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population" @default.
• W2055246505 cites W1605691217 @default.
• W2055246505 cites W1968964429 @default.
• W2055246505 cites W1971940291 @default.
• W2055246505 cites W1991119112 @default.
• W2055246505 cites W1999239960 @default.
• W2055246505 cites W2001105894 @default.
• W2055246505 cites W2002100378 @default.
• W2055246505 cites W2020458600 @default.
• W2055246505 cites W2026207762 @default.
• W2055246505 cites W2041816914 @default.
• W2055246505 cites W2043897262 @default.
• W2055246505 cites W2052407549 @default.
• W2055246505 cites W2054574487 @default.
• W2055246505 cites W2058401000 @default.
• W2055246505 cites W2060568244 @default.
• W2055246505 cites W2064999239 @default.
• W2055246505 cites W2067484335 @default.
• W2055246505 cites W2092641932 @default.
• W2055246505 cites W2099871303 @default.
• W2055246505 cites W2101791609 @default.
• W2055246505 cites W2103362609 @default.
• W2055246505 cites W2111904430 @default.
• W2055246505 cites W2115523644 @default.
• W2055246505 cites W2120321361 @default.
• W2055246505 cites W2120483845 @default.
• W2055246505 cites W2152924568 @default.
• W2055246505 cites W2155635136 @default.
• W2055246505 cites W2156989422 @default.
• W2055246505 cites W2157259406 @default.
• W2055246505 cites W2159356657 @default.
• W2055246505 cites W2159852502 @default.
• W2055246505 cites W2162530578 @default.
• W2055246505 cites W2165026044 @default.
• W2055246505 cites W2167629238 @default.
• W2055246505 cites W2168715864 @default.
• W2055246505 cites W2217809488 @default.
• W2055246505 cites W2302584066 @default.
• W2055246505 cites W4297819594 @default.
• W2055246505 doi "https://doi.org/10.1016/j.joca.2008.12.012" @default.
• W2055246505 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19341834" @default.
• W2055246505 hasPublicationYear "2009" @default.
• W2055246505 type Work @default.
• W2055246505 sameAs 2055246505 @default.
• W2055246505 citedByCount "29" @default.
• W2055246505 countsByYear W20552465052012 @default.
• W2055246505 countsByYear W20552465052013 @default.
• W2055246505 countsByYear W20552465052014 @default.
• W2055246505 countsByYear W20552465052015 @default.
• W2055246505 countsByYear W20552465052016 @default.
• W2055246505 countsByYear W20552465052018 @default.
• W2055246505 countsByYear W20552465052019 @default.
• W2055246505 countsByYear W20552465052020 @default.
• W2055246505 countsByYear W20552465052021 @default.
• W2055246505 countsByYear W20552465052022 @default.
• W2055246505 countsByYear W20552465052023 @default.
• W2055246505 crossrefType "journal-article" @default.
• W2055246505 hasAuthorship W2055246505A5013374671 @default.
• W2055246505 hasAuthorship W2055246505A5019865477 @default.
• W2055246505 hasAuthorship W2055246505A5028565837 @default.
• W2055246505 hasAuthorship W2055246505A5034851133 @default.
• W2055246505 hasAuthorship W2055246505A5041403850 @default.
• W2055246505 hasAuthorship W2055246505A5044204023 @default.
• W2055246505 hasAuthorship W2055246505A5057288832 @default.
• W2055246505 hasAuthorship W2055246505A5066521398 @default.
• W2055246505 hasAuthorship W2055246505A5079912358 @default.
• W2055246505 hasBestOaLocation W20552465051 @default.
• W2055246505 hasConcept C104317684 @default.
• W2055246505 hasConcept C135763542 @default.
• W2055246505 hasConcept C153209595 @default.
• W2055246505 hasConcept C180754005 @default.
• W2055246505 hasConcept C186413461 @default.
• W2055246505 hasConcept C197754878 @default.
• W2055246505 hasConcept C2776885448 @default.
• W2055246505 hasConcept C2908647359 @default.
• W2055246505 hasConcept C35605836 @default.
• W2055246505 hasConcept C54355233 @default.
• W2055246505 hasConcept C69991583 @default.
• W2055246505 hasConcept C71924100 @default.
• W2055246505 hasConcept C84597430 @default.
• W2055246505 hasConcept C86803240 @default.
• W2055246505 hasConcept C99454951 @default.
• W2055246505 hasConceptScore W2055246505C104317684 @default.
• W2055246505 hasConceptScore W2055246505C135763542 @default.
• W2055246505 hasConceptScore W2055246505C153209595 @default.

• next