Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055295116> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2055295116 endingPage "2816" @default.
- W2055295116 startingPage "2810" @default.
- W2055295116 abstract "Three patients with human immunodeficiency virus (HIV) infection presented with QTc prolongation (> 440 ms) and torsades de pointes. We sought to evaluate the etiology of the long QT syndrome in these patients without previously identified causes for QTc prolongation, and determine the prevalence among patients with HIV infection. The three index patients underwent: (1) left stellate ganglion block; (2) β-blocker challenge; and (3) electrocardiographic stress testing. QTc interval was measured before and after intervention. We undertook a retrospective analysis of prevalence of QTc prolongation among all patients with computerized ECGs over a 6-month period at one institution and compared it to the prevalence in hospitalized patients with HIV disease. Thirty-four thousand one hundred eighty-one patients with computerized ECGs were screened for QTc prolongation. Forty-two hospitalized patients with HIV disease had computerized ECG during the same 6-month period. In the three index patients, the QTc failed to shorten with left stellate ganglion blockade, β-blocker challenge, or stress testing, suggesting an acquired form of the long QT syndrome in these patients with HIV disease. None had previously recognized acquired causes of QTc prolongation. Mexiletine hydrochloride was useful in preventing recurrences of torsades de pointes. We observed a 7.0% prevalence of QTc prolongation among all patients screened. Hospitalized patients with HIV disease (n = 42) during this same period, demonstrated an increased prevalence of QTc prolongation (28.6%, P = 0.002). Patients with HIV disease have a significantly higher prevalence of QTc prolongation than a general hospital-based population, may have an unrecognized acquired form of the long QT syndrome, and are at risk for torsades de pointes." @default.
- W2055295116 created "2016-06-24" @default.
- W2055295116 creator A5024640899 @default.
- W2055295116 creator A5041557267 @default.
- W2055295116 creator A5054873677 @default.
- W2055295116 creator A5071705296 @default.
- W2055295116 date "1997-11-01" @default.
- W2055295116 modified "2023-10-14" @default.
- W2055295116 title "Long QTc and Torsades de Pointes in Human Immunodeficiency Virus Disease" @default.
- W2055295116 cites W1968614065 @default.
- W2055295116 cites W1972410710 @default.
- W2055295116 cites W1976243616 @default.
- W2055295116 cites W1986457340 @default.
- W2055295116 cites W1991290782 @default.
- W2055295116 cites W1999000941 @default.
- W2055295116 cites W2020116601 @default.
- W2055295116 cites W2033726041 @default.
- W2055295116 cites W2036909923 @default.
- W2055295116 cites W2047989871 @default.
- W2055295116 cites W2056253207 @default.
- W2055295116 cites W2063027814 @default.
- W2055295116 cites W2063242638 @default.
- W2055295116 cites W2065502432 @default.
- W2055295116 cites W2068809529 @default.
- W2055295116 cites W2071282407 @default.
- W2055295116 cites W2072891464 @default.
- W2055295116 cites W2075258511 @default.
- W2055295116 cites W2093914504 @default.
- W2055295116 cites W2123517830 @default.
- W2055295116 cites W2319980369 @default.
- W2055295116 doi "https://doi.org/10.1111/j.1540-8159.1997.tb05439.x" @default.
- W2055295116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9392812" @default.
- W2055295116 hasPublicationYear "1997" @default.
- W2055295116 type Work @default.
- W2055295116 sameAs 2055295116 @default.
- W2055295116 citedByCount "95" @default.
- W2055295116 countsByYear W20552951162012 @default.
- W2055295116 countsByYear W20552951162013 @default.
- W2055295116 countsByYear W20552951162014 @default.
- W2055295116 countsByYear W20552951162015 @default.
- W2055295116 countsByYear W20552951162016 @default.
- W2055295116 countsByYear W20552951162017 @default.
- W2055295116 countsByYear W20552951162018 @default.
- W2055295116 countsByYear W20552951162019 @default.
- W2055295116 countsByYear W20552951162020 @default.
- W2055295116 countsByYear W20552951162022 @default.
- W2055295116 crossrefType "journal-article" @default.
- W2055295116 hasAuthorship W2055295116A5024640899 @default.
- W2055295116 hasAuthorship W2055295116A5041557267 @default.
- W2055295116 hasAuthorship W2055295116A5054873677 @default.
- W2055295116 hasAuthorship W2055295116A5071705296 @default.
- W2055295116 hasConcept C118441451 @default.
- W2055295116 hasConcept C126322002 @default.
- W2055295116 hasConcept C164705383 @default.
- W2055295116 hasConcept C2777561782 @default.
- W2055295116 hasConcept C2777672339 @default.
- W2055295116 hasConcept C2779703243 @default.
- W2055295116 hasConcept C2780040984 @default.
- W2055295116 hasConcept C2780486423 @default.
- W2055295116 hasConcept C2908647359 @default.
- W2055295116 hasConcept C42219234 @default.
- W2055295116 hasConcept C71924100 @default.
- W2055295116 hasConcept C99454951 @default.
- W2055295116 hasConceptScore W2055295116C118441451 @default.
- W2055295116 hasConceptScore W2055295116C126322002 @default.
- W2055295116 hasConceptScore W2055295116C164705383 @default.
- W2055295116 hasConceptScore W2055295116C2777561782 @default.
- W2055295116 hasConceptScore W2055295116C2777672339 @default.
- W2055295116 hasConceptScore W2055295116C2779703243 @default.
- W2055295116 hasConceptScore W2055295116C2780040984 @default.
- W2055295116 hasConceptScore W2055295116C2780486423 @default.
- W2055295116 hasConceptScore W2055295116C2908647359 @default.
- W2055295116 hasConceptScore W2055295116C42219234 @default.
- W2055295116 hasConceptScore W2055295116C71924100 @default.
- W2055295116 hasConceptScore W2055295116C99454951 @default.
- W2055295116 hasIssue "11" @default.
- W2055295116 hasLocation W20552951161 @default.
- W2055295116 hasLocation W20552951162 @default.
- W2055295116 hasOpenAccess W2055295116 @default.
- W2055295116 hasPrimaryLocation W20552951161 @default.
- W2055295116 hasRelatedWork W1976316391 @default.
- W2055295116 hasRelatedWork W2029993982 @default.
- W2055295116 hasRelatedWork W2060105258 @default.
- W2055295116 hasRelatedWork W2087234566 @default.
- W2055295116 hasRelatedWork W2118657370 @default.
- W2055295116 hasRelatedWork W3092593366 @default.
- W2055295116 hasRelatedWork W3094909023 @default.
- W2055295116 hasRelatedWork W3110574997 @default.
- W2055295116 hasRelatedWork W4225149150 @default.
- W2055295116 hasRelatedWork W4291786306 @default.
- W2055295116 hasVolume "20" @default.
- W2055295116 isParatext "false" @default.
- W2055295116 isRetracted "false" @default.
- W2055295116 magId "2055295116" @default.
- W2055295116 workType "article" @default.