FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055306369> ?p ?o ?g. }

• W2055306369 endingPage "38" @default.
• W2055306369 startingPage "32" @default.
• W2055306369 abstract "Poly(ϵ-caprolactone) (PCL) membranes loaded with Linezolid, chemically N-[[(5S)-3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide (empirical formula C16H20FN3O4) have been prepared by electrospinning technique, at different Linezolid concentrations (0.5, 1, 2.5 and 5%, w/w). Structural characterization, morphological analysis and the study of the mechanical properties have been performed on loaded membranes and compared with neat PCL membranes. Linezolid embedded in the membranes is prevalently amorphous, with a low crystallinity showing a different polymorphic form respect to the usual Form I and Form II. The release kinetics of the drug were studied by spectrophotometric analysis (UV–vis). It allowed to discriminate between Linezolid molecules on the surface and encapsulated into the fibers. The antibacterial activity of the electrospun membranes was effective to inhibit Staphylococcus aureus. The properties of the loaded membranes and their capability for local delivery of the antibiotic make them good candidates as drug release devices for topical use." @default.
• W2055306369 created "2016-06-24" @default.
• W2055306369 creator A5007339780 @default.
• W2055306369 creator A5012081495 @default.
• W2055306369 creator A5024605648 @default.
• W2055306369 creator A5068592584 @default.
• W2055306369 creator A5088055163 @default.
• W2055306369 date "2015-07-01" @default.
• W2055306369 modified "2023-09-27" @default.
• W2055306369 title "Polymorphic solidification of Linezolid confined in electrospun PCL fibers for controlled release in topical applications" @default.
• W2055306369 cites W1975535993 @default.
• W2055306369 cites W1984418916 @default.
• W2055306369 cites W1993093350 @default.
• W2055306369 cites W1997552417 @default.
• W2055306369 cites W2001633027 @default.
• W2055306369 cites W2043132922 @default.
• W2055306369 cites W2055475096 @default.
• W2055306369 cites W2065728895 @default.
• W2055306369 cites W2091415490 @default.
• W2055306369 cites W2113176657 @default.
• W2055306369 cites W2120893358 @default.
• W2055306369 cites W2141539405 @default.
• W2055306369 cites W2142720627 @default.
• W2055306369 cites W2153039659 @default.
• W2055306369 cites W2157248428 @default.
• W2055306369 cites W2168635615 @default.
• W2055306369 doi "https://doi.org/10.1016/j.ijpharm.2015.04.070" @default.
• W2055306369 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25934427" @default.
• W2055306369 hasPublicationYear "2015" @default.
• W2055306369 type Work @default.
• W2055306369 sameAs 2055306369 @default.
• W2055306369 citedByCount "22" @default.
• W2055306369 countsByYear W20553063692016 @default.
• W2055306369 countsByYear W20553063692017 @default.
• W2055306369 countsByYear W20553063692019 @default.
• W2055306369 countsByYear W20553063692020 @default.
• W2055306369 countsByYear W20553063692021 @default.
• W2055306369 countsByYear W20553063692022 @default.
• W2055306369 countsByYear W20553063692023 @default.
• W2055306369 crossrefType "journal-article" @default.
• W2055306369 hasAuthorship W2055306369A5007339780 @default.
• W2055306369 hasAuthorship W2055306369A5012081495 @default.
• W2055306369 hasAuthorship W2055306369A5024605648 @default.
• W2055306369 hasAuthorship W2055306369A5068592584 @default.
• W2055306369 hasAuthorship W2055306369A5088055163 @default.
• W2055306369 hasBestOaLocation W20553063692 @default.
• W2055306369 hasConcept C127413603 @default.
• W2055306369 hasConcept C144796933 @default.
• W2055306369 hasConcept C159985019 @default.
• W2055306369 hasConcept C178790620 @default.
• W2055306369 hasConcept C185592680 @default.
• W2055306369 hasConcept C192562407 @default.
• W2055306369 hasConcept C2778980435 @default.
• W2055306369 hasConcept C2779489039 @default.
• W2055306369 hasConcept C2781414143 @default.
• W2055306369 hasConcept C41625074 @default.
• W2055306369 hasConcept C42360764 @default.
• W2055306369 hasConcept C46275449 @default.
• W2055306369 hasConcept C521977710 @default.
• W2055306369 hasConcept C523546767 @default.
• W2055306369 hasConcept C54355233 @default.
• W2055306369 hasConcept C55493867 @default.
• W2055306369 hasConcept C56052488 @default.
• W2055306369 hasConcept C86803240 @default.
• W2055306369 hasConceptScore W2055306369C127413603 @default.
• W2055306369 hasConceptScore W2055306369C144796933 @default.
• W2055306369 hasConceptScore W2055306369C159985019 @default.
• W2055306369 hasConceptScore W2055306369C178790620 @default.
• W2055306369 hasConceptScore W2055306369C185592680 @default.
• W2055306369 hasConceptScore W2055306369C192562407 @default.
• W2055306369 hasConceptScore W2055306369C2778980435 @default.
• W2055306369 hasConceptScore W2055306369C2779489039 @default.
• W2055306369 hasConceptScore W2055306369C2781414143 @default.
• W2055306369 hasConceptScore W2055306369C41625074 @default.
• W2055306369 hasConceptScore W2055306369C42360764 @default.
• W2055306369 hasConceptScore W2055306369C46275449 @default.
• W2055306369 hasConceptScore W2055306369C521977710 @default.
• W2055306369 hasConceptScore W2055306369C523546767 @default.
• W2055306369 hasConceptScore W2055306369C54355233 @default.
• W2055306369 hasConceptScore W2055306369C55493867 @default.
• W2055306369 hasConceptScore W2055306369C56052488 @default.
• W2055306369 hasConceptScore W2055306369C86803240 @default.
• W2055306369 hasIssue "1-2" @default.
• W2055306369 hasLocation W20553063691 @default.
• W2055306369 hasLocation W20553063692 @default.
• W2055306369 hasLocation W20553063693 @default.
• W2055306369 hasOpenAccess W2055306369 @default.
• W2055306369 hasPrimaryLocation W20553063691 @default.
• W2055306369 hasRelatedWork W1972597629 @default.
• W2055306369 hasRelatedWork W1979046316 @default.
• W2055306369 hasRelatedWork W2045367585 @default.
• W2055306369 hasRelatedWork W2049555234 @default.
• W2055306369 hasRelatedWork W2251293103 @default.
• W2055306369 hasRelatedWork W2779364675 @default.
• W2055306369 hasRelatedWork W3192851454 @default.
• W2055306369 hasRelatedWork W4284881905 @default.
• W2055306369 hasRelatedWork W4290964060 @default.
• W2055306369 hasRelatedWork W4367311182 @default.

• next