FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055308877> ?p ?o ?g. }

• W2055308877 endingPage "745" @default.
• W2055308877 startingPage "738" @default.
• W2055308877 abstract "This study was initiated to test the hypothesis that fetal hemodynamic changes observed under pulsatile flow bypass might be related to the release of endothelium-derived relaxing factor through oscillating shear stress.Normothermic bypass was instituted in utero in 21 preterm fetal lambs for a 1-hour period through the right atrium and main pulmonary artery. Ultrasonic flowmeters were positioned around the descending aorta and the umbilical artery. The circuit consisted of an oxygenator and a pump set to either continuous flow (n = 7) or pulsatile flow (n = 7) and adjusted to maintain a fetal main arterial pressure of 50 mm Hg. In seven other animals, endothelium-derived relaxing factor was blocked by a continuous infusion of N omega-nitro-L-arginine after 30 minutes of pulsatile flow.During the first 30 minutes of bypass, pump flows were significantly lower in the continuous-flow group than in the pulsatile-flow or blocked-flow groups (respectively, 612 +/- 144, 907 +/- 153 and 987 +/- 228 ml/min), with similar changes in aortic and umbilical flows. Systemic vascular resistances were significantly lower in the pulsatile-flow and blocked-flow groups than in the continuous-flow group (550 +/- 106 vs 821 +/- 212 dynes/sec/cm-5). However, after blockade of endothelium-derived relaxing factor, resistances increased gradually in the blocked-flow group to reach the level of that of the continuous-flow group at the end of bypass (943 +/- 77 vs 556 +/- 143 dynes/sec/cm-5 in the pulsatile-flow group).Blockade of endothelium-derived relaxing factor after 30 minutes of pulsatile flow returns fetal hemodynamics to continuous flow conditions. The specific inhibitor of endothelium-derived relaxing factor used in this experiment suggests that nitric oxide may be released by fetal endothelium during pulsatile bypass." @default.
• W2055308877 created "2016-06-24" @default.
• W2055308877 creator A5005416698 @default.
• W2055308877 creator A5014752496 @default.
• W2055308877 creator A5015879995 @default.
• W2055308877 creator A5036836400 @default.
• W2055308877 creator A5042123181 @default.
• W2055308877 creator A5059238607 @default.
• W2055308877 creator A5070191280 @default.
• W2055308877 date "1997-11-01" @default.
• W2055308877 modified "2023-10-14" @default.
• W2055308877 title "Flow-induced release of endothelium-derived relaxing factor during pulsatile bypass: Experimental study in the fetal lamb" @default.
• W2055308877 cites W1870890372 @default.
• W2055308877 cites W1947755567 @default.
• W2055308877 cites W1987713060 @default.
• W2055308877 cites W2012544168 @default.
• W2055308877 cites W2049517700 @default.
• W2055308877 cites W2052366845 @default.
• W2055308877 cites W2066580637 @default.
• W2055308877 cites W2085084930 @default.
• W2055308877 cites W2169182236 @default.
• W2055308877 cites W2327269495 @default.
• W2055308877 cites W2462771960 @default.
• W2055308877 cites W2509613728 @default.
• W2055308877 cites W4241099751 @default.
• W2055308877 cites W4298311268 @default.
• W2055308877 doi "https://doi.org/10.1016/s0022-5223(97)70077-1" @default.
• W2055308877 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9375603" @default.
• W2055308877 hasPublicationYear "1997" @default.
• W2055308877 type Work @default.
• W2055308877 sameAs 2055308877 @default.
• W2055308877 citedByCount "41" @default.
• W2055308877 countsByYear W20553088772012 @default.
• W2055308877 countsByYear W20553088772013 @default.
• W2055308877 countsByYear W20553088772014 @default.
• W2055308877 countsByYear W20553088772015 @default.
• W2055308877 countsByYear W20553088772017 @default.
• W2055308877 countsByYear W20553088772018 @default.
• W2055308877 countsByYear W20553088772021 @default.
• W2055308877 crossrefType "journal-article" @default.
• W2055308877 hasAuthorship W2055308877A5005416698 @default.
• W2055308877 hasAuthorship W2055308877A5014752496 @default.
• W2055308877 hasAuthorship W2055308877A5015879995 @default.
• W2055308877 hasAuthorship W2055308877A5036836400 @default.
• W2055308877 hasAuthorship W2055308877A5042123181 @default.
• W2055308877 hasAuthorship W2055308877A5059238607 @default.
• W2055308877 hasAuthorship W2055308877A5070191280 @default.
• W2055308877 hasBestOaLocation W20553088771 @default.
• W2055308877 hasConcept C126322002 @default.
• W2055308877 hasConcept C164705383 @default.
• W2055308877 hasConcept C172680121 @default.
• W2055308877 hasConcept C178853913 @default.
• W2055308877 hasConcept C2776992346 @default.
• W2055308877 hasConcept C2778881276 @default.
• W2055308877 hasConcept C2778964498 @default.
• W2055308877 hasConcept C2779055493 @default.
• W2055308877 hasConcept C2779234561 @default.
• W2055308877 hasConcept C2780310817 @default.
• W2055308877 hasConcept C42219234 @default.
• W2055308877 hasConcept C54355233 @default.
• W2055308877 hasConcept C58245268 @default.
• W2055308877 hasConcept C71924100 @default.
• W2055308877 hasConcept C79191276 @default.
• W2055308877 hasConcept C86803240 @default.
• W2055308877 hasConceptScore W2055308877C126322002 @default.
• W2055308877 hasConceptScore W2055308877C164705383 @default.
• W2055308877 hasConceptScore W2055308877C172680121 @default.
• W2055308877 hasConceptScore W2055308877C178853913 @default.
• W2055308877 hasConceptScore W2055308877C2776992346 @default.
• W2055308877 hasConceptScore W2055308877C2778881276 @default.
• W2055308877 hasConceptScore W2055308877C2778964498 @default.
• W2055308877 hasConceptScore W2055308877C2779055493 @default.
• W2055308877 hasConceptScore W2055308877C2779234561 @default.
• W2055308877 hasConceptScore W2055308877C2780310817 @default.
• W2055308877 hasConceptScore W2055308877C42219234 @default.
• W2055308877 hasConceptScore W2055308877C54355233 @default.
• W2055308877 hasConceptScore W2055308877C58245268 @default.
• W2055308877 hasConceptScore W2055308877C71924100 @default.
• W2055308877 hasConceptScore W2055308877C79191276 @default.
• W2055308877 hasConceptScore W2055308877C86803240 @default.
• W2055308877 hasIssue "5" @default.
• W2055308877 hasLocation W20553088771 @default.
• W2055308877 hasLocation W20553088772 @default.
• W2055308877 hasOpenAccess W2055308877 @default.
• W2055308877 hasPrimaryLocation W20553088771 @default.
• W2055308877 hasRelatedWork W111119222 @default.
• W2055308877 hasRelatedWork W1982466137 @default.
• W2055308877 hasRelatedWork W1998669242 @default.
• W2055308877 hasRelatedWork W2068076496 @default.
• W2055308877 hasRelatedWork W2070116989 @default.
• W2055308877 hasRelatedWork W2082724546 @default.
• W2055308877 hasRelatedWork W2085955295 @default.
• W2055308877 hasRelatedWork W2194519063 @default.
• W2055308877 hasRelatedWork W2405148523 @default.
• W2055308877 hasRelatedWork W4386383647 @default.
• W2055308877 hasVolume "114" @default.
• W2055308877 isParatext "false" @default.
• W2055308877 isRetracted "false" @default.

• next