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- W2055356469 abstract "“Encéphale isolé” cats were implanted with three push-pull cannulae. The two caudate nuclei (CN) were superfused continuously with 3 H-tyrosine to measure the release of 3 H-DA in serially collected fractions. Three hours after the beginning of the experiment, d,l-baclofen, d- or l-baclofen or γ-hydroxybaclofen were introduced for 15 min in the medium used to superfuse the left substantia nigra. d,l-Baclofen (10 −6 M) stimulated 3 H-DA release in the ipsilateral as well as in the contralateral CN but the effect was more pronounced in the ipsilateral CN. Similar effects were observed with l-Baclofen and γ-hydroxybaclofen were inactive. The results obtained are discussed in the light of effects previously observed during the nigral application of γ-aminobutyric acid (GABA) and related compounds." @default.
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- W2055356469 date "1979-09-01" @default.
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- W2055356469 title "Effects of the unilateral nigral application of baclofen on dopamine release in the two caudate nuclei of the cat" @default.
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- W2055356469 doi "https://doi.org/10.1016/0014-2999(79)90004-9" @default.
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