FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055366963> ?p ?o ?g. }

• W2055366963 endingPage "2779" @default.
• W2055366963 startingPage "2774" @default.
• W2055366963 abstract "Ryanodine receptors (RyRs) are a family of Ca2+ channel proteins that mediate the massive release of Ca2+ from the endoplasmic reticulum into the cytoplasma. In the present study, we manipulated the incorporation of RyR1 into RBC membrane and investigated its influences on the intracellular Ca2+ ([Ca2+]in) level and the biomechanical properties in RBCs. The incorporation of RyR1 into RBC membranes was demonstrated by both immunofluorescent staining and the change of [Ca2+]in of RBCs. In the presence of RyR1, [Ca2+]in showed biphasic changes, i.e., it increased with the extracellular Ca2+ ([Ca2+]ex) up to 5 μM and then decreased with the further increase of [Ca2+]ex. However, [Ca2+]in remained constant in the absence of the RyR1. The results of biomechanical measurements on RBCs, including deformability, osmotic fragility, and membrane microviscosity, reflected similar biphasic changes of [Ca2+]in mediated by RyR1 with the increases of [Ca2+]ex. Therefore, it is believed that RyR1 can incorporate into RBC membrane in vitro, and mediate Ca2+ influx, and then regulate RBC biomechanical properties. This information suggests that RBCs may serve as a model to study the function of RyR1 as a Ca2+ release channel." @default.
• W2055366963 created "2016-06-24" @default.
• W2055366963 creator A5000001986 @default.
• W2055366963 creator A5008171524 @default.
• W2055366963 creator A5015695593 @default.
• W2055366963 creator A5017102600 @default.
• W2055366963 creator A5019383992 @default.
• W2055366963 creator A5029285177 @default.
• W2055366963 creator A5029762264 @default.
• W2055366963 creator A5046138454 @default.
• W2055366963 creator A5050305033 @default.
• W2055366963 creator A5068335042 @default.
• W2055366963 creator A5076409244 @default.
• W2055366963 creator A5086783805 @default.
• W2055366963 date "2009-12-01" @default.
• W2055366963 modified "2023-09-25" @default.
• W2055366963 title "Ryanodine receptor 1 mediates Ca2+ transport and influences the biomechanical properties in RBCs" @default.
• W2055366963 cites W1489147273 @default.
• W2055366963 cites W1740533879 @default.
• W2055366963 cites W1908503020 @default.
• W2055366963 cites W1972790319 @default.
• W2055366963 cites W1980898315 @default.
• W2055366963 cites W1982260352 @default.
• W2055366963 cites W1985175350 @default.
• W2055366963 cites W1991486039 @default.
• W2055366963 cites W2010370972 @default.
• W2055366963 cites W2010538547 @default.
• W2055366963 cites W2011038097 @default.
• W2055366963 cites W2016327151 @default.
• W2055366963 cites W2020672475 @default.
• W2055366963 cites W2022587437 @default.
• W2055366963 cites W2040053115 @default.
• W2055366963 cites W2045583936 @default.
• W2055366963 cites W2047383843 @default.
• W2055366963 cites W2049491065 @default.
• W2055366963 cites W2052739933 @default.
• W2055366963 cites W2076408588 @default.
• W2055366963 cites W2078062330 @default.
• W2055366963 cites W2078734388 @default.
• W2055366963 cites W2093557558 @default.
• W2055366963 cites W2095169311 @default.
• W2055366963 cites W2113076389 @default.
• W2055366963 cites W2123384023 @default.
• W2055366963 cites W2137283585 @default.
• W2055366963 cites W2138450406 @default.
• W2055366963 cites W2162047059 @default.
• W2055366963 cites W2307195668 @default.
• W2055366963 cites W2437900641 @default.
• W2055366963 doi "https://doi.org/10.1016/j.jbiomech.2009.07.036" @default.
• W2055366963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19767002" @default.
• W2055366963 hasPublicationYear "2009" @default.
• W2055366963 type Work @default.
• W2055366963 sameAs 2055366963 @default.
• W2055366963 citedByCount "1" @default.
• W2055366963 countsByYear W20553669632015 @default.
• W2055366963 crossrefType "journal-article" @default.
• W2055366963 hasAuthorship W2055366963A5000001986 @default.
• W2055366963 hasAuthorship W2055366963A5008171524 @default.
• W2055366963 hasAuthorship W2055366963A5015695593 @default.
• W2055366963 hasAuthorship W2055366963A5017102600 @default.
• W2055366963 hasAuthorship W2055366963A5019383992 @default.
• W2055366963 hasAuthorship W2055366963A5029285177 @default.
• W2055366963 hasAuthorship W2055366963A5029762264 @default.
• W2055366963 hasAuthorship W2055366963A5046138454 @default.
• W2055366963 hasAuthorship W2055366963A5050305033 @default.
• W2055366963 hasAuthorship W2055366963A5068335042 @default.
• W2055366963 hasAuthorship W2055366963A5076409244 @default.
• W2055366963 hasAuthorship W2055366963A5086783805 @default.
• W2055366963 hasConcept C113217602 @default.
• W2055366963 hasConcept C12554922 @default.
• W2055366963 hasConcept C158617107 @default.
• W2055366963 hasConcept C185592680 @default.
• W2055366963 hasConcept C2776333580 @default.
• W2055366963 hasConcept C28406088 @default.
• W2055366963 hasConcept C79879829 @default.
• W2055366963 hasConcept C86803240 @default.
• W2055366963 hasConcept C95444343 @default.
• W2055366963 hasConceptScore W2055366963C113217602 @default.
• W2055366963 hasConceptScore W2055366963C12554922 @default.
• W2055366963 hasConceptScore W2055366963C158617107 @default.
• W2055366963 hasConceptScore W2055366963C185592680 @default.
• W2055366963 hasConceptScore W2055366963C2776333580 @default.
• W2055366963 hasConceptScore W2055366963C28406088 @default.
• W2055366963 hasConceptScore W2055366963C79879829 @default.
• W2055366963 hasConceptScore W2055366963C86803240 @default.
• W2055366963 hasConceptScore W2055366963C95444343 @default.
• W2055366963 hasIssue "16" @default.
• W2055366963 hasLocation W20553669631 @default.
• W2055366963 hasLocation W20553669632 @default.
• W2055366963 hasOpenAccess W2055366963 @default.
• W2055366963 hasPrimaryLocation W20553669631 @default.
• W2055366963 hasRelatedWork W177664591 @default.
• W2055366963 hasRelatedWork W1940380171 @default.
• W2055366963 hasRelatedWork W1986199038 @default.
• W2055366963 hasRelatedWork W2007278059 @default.
• W2055366963 hasRelatedWork W2009015132 @default.
• W2055366963 hasRelatedWork W2071218737 @default.
• W2055366963 hasRelatedWork W2108366599 @default.

• next