FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055409569> ?p ?o ?g. }

• W2055409569 endingPage "445" @default.
• W2055409569 startingPage "439" @default.
• W2055409569 abstract "Wastewater treatment plant (WWTP) effluents can contain estrogenic chemicals, which potentially disrupt fish reproduction and development. The current study focused on the use of an estrogen-responsive in vitro cell bioassay (T47D-KBluc), to quantify total estrogenicity of WWTP effluents. We tested a novel sample preparation method for the T47D-KBluc assay, using powdered media prepared with direct effluent. Results of the T47D-KBluc assay were compared with the induction of estrogen receptor–regulated gene transcription in male fathead minnows (Pimephales promelas) exposed to the same effluents. Effluent samples for the paired studies were collected over the course of three months. According to the T47D-KBluc assay, the effluent estrogenicity ranged from 1.13 to 2.00 ng 17β-estradiol (E2) equivalents/L. Corresponding in vivo studies exposing male fathead minnows to 0, 10, 50, and 100% effluent dilutions demonstrated that exposure to 100% effluent significantly increased hepatic vitellogenin (VTG) and estrogen receptor α subunit transcripts relative to controls. The induction was also significant in males exposed to 250 ng E2/L or 100 ng E2/L. The in vitro and in vivo results support the conclusion that the effluent contains significant estrogenic activity, but there was a discrepancy between in vitro– and in vivo–based E2 equivalent estimates. Our results suggest that the direct effluent preparation method for the T47D-KBluc assay is a reasonable approach to estimate the estrogenicity of wastewater effluent. Environ. Toxicol. Chem. 2011;30:439–445. © 2010 SETAC" @default.
• W2055409569 created "2016-06-24" @default.
• W2055409569 creator A5000553285 @default.
• W2055409569 creator A5002492131 @default.
• W2055409569 creator A5037354780 @default.
• W2055409569 creator A5038610645 @default.
• W2055409569 creator A5044171138 @default.
• W2055409569 creator A5068036674 @default.
• W2055409569 creator A5076817494 @default.
• W2055409569 creator A5086018874 @default.
• W2055409569 creator A5090759778 @default.
• W2055409569 date "2010-12-10" @default.
• W2055409569 modified "2023-10-02" @default.
• W2055409569 title "Screening complex effluents for estrogenic activity with the T47D-KBluc cell bioassay: Assay optimization and comparison with in vivo responses in fish" @default.
• W2055409569 cites W1970522623 @default.
• W2055409569 cites W1987011930 @default.
• W2055409569 cites W1989047389 @default.
• W2055409569 cites W1995202257 @default.
• W2055409569 cites W2002481914 @default.
• W2055409569 cites W2005017547 @default.
• W2055409569 cites W2021752630 @default.
• W2055409569 cites W2023666759 @default.
• W2055409569 cites W2036139751 @default.
• W2055409569 cites W2045972457 @default.
• W2055409569 cites W2051607653 @default.
• W2055409569 cites W2073586579 @default.
• W2055409569 cites W2073876098 @default.
• W2055409569 cites W2088415060 @default.
• W2055409569 cites W2103835764 @default.
• W2055409569 cites W2107250606 @default.
• W2055409569 cites W2115815500 @default.
• W2055409569 cites W2116717043 @default.
• W2055409569 cites W2118019986 @default.
• W2055409569 cites W2119745101 @default.
• W2055409569 cites W2120725343 @default.
• W2055409569 cites W2136881537 @default.
• W2055409569 cites W2145907641 @default.
• W2055409569 cites W2151457406 @default.
• W2055409569 cites W2151486223 @default.
• W2055409569 cites W2169412126 @default.
• W2055409569 cites W295840756 @default.
• W2055409569 cites W4250160850 @default.
• W2055409569 doi "https://doi.org/10.1002/etc.388" @default.
• W2055409569 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21038435" @default.
• W2055409569 hasPublicationYear "2010" @default.
• W2055409569 type Work @default.
• W2055409569 sameAs 2055409569 @default.
• W2055409569 citedByCount "30" @default.
• W2055409569 countsByYear W20554095692012 @default.
• W2055409569 countsByYear W20554095692013 @default.
• W2055409569 countsByYear W20554095692014 @default.
• W2055409569 countsByYear W20554095692015 @default.
• W2055409569 countsByYear W20554095692016 @default.
• W2055409569 countsByYear W20554095692017 @default.
• W2055409569 countsByYear W20554095692018 @default.
• W2055409569 countsByYear W20554095692019 @default.
• W2055409569 countsByYear W20554095692020 @default.
• W2055409569 countsByYear W20554095692021 @default.
• W2055409569 countsByYear W20554095692022 @default.
• W2055409569 countsByYear W20554095692023 @default.
• W2055409569 crossrefType "journal-article" @default.
• W2055409569 hasAuthorship W2055409569A5000553285 @default.
• W2055409569 hasAuthorship W2055409569A5002492131 @default.
• W2055409569 hasAuthorship W2055409569A5037354780 @default.
• W2055409569 hasAuthorship W2055409569A5038610645 @default.
• W2055409569 hasAuthorship W2055409569A5044171138 @default.
• W2055409569 hasAuthorship W2055409569A5068036674 @default.
• W2055409569 hasAuthorship W2055409569A5076817494 @default.
• W2055409569 hasAuthorship W2055409569A5086018874 @default.
• W2055409569 hasAuthorship W2055409569A5090759778 @default.
• W2055409569 hasConcept C104488531 @default.
• W2055409569 hasConcept C107872376 @default.
• W2055409569 hasConcept C121608353 @default.
• W2055409569 hasConcept C134018914 @default.
• W2055409569 hasConcept C142724271 @default.
• W2055409569 hasConcept C147455438 @default.
• W2055409569 hasConcept C150903083 @default.
• W2055409569 hasConcept C184112429 @default.
• W2055409569 hasConcept C185592680 @default.
• W2055409569 hasConcept C18903297 @default.
• W2055409569 hasConcept C204787440 @default.
• W2055409569 hasConcept C207001950 @default.
• W2055409569 hasConcept C2776451064 @default.
• W2055409569 hasConcept C2777164284 @default.
• W2055409569 hasConcept C2779078696 @default.
• W2055409569 hasConcept C2909208804 @default.
• W2055409569 hasConcept C2993305272 @default.
• W2055409569 hasConcept C39432304 @default.
• W2055409569 hasConcept C43617362 @default.
• W2055409569 hasConcept C505870484 @default.
• W2055409569 hasConcept C530470458 @default.
• W2055409569 hasConcept C54355233 @default.
• W2055409569 hasConcept C71924100 @default.
• W2055409569 hasConcept C84606932 @default.
• W2055409569 hasConcept C86803240 @default.
• W2055409569 hasConcept C87717796 @default.
• W2055409569 hasConcept C98274493 @default.
• W2055409569 hasConceptScore W2055409569C104488531 @default.

• next