Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055443337> ?p ?o ?g. }
- W2055443337 endingPage "145" @default.
- W2055443337 startingPage "142" @default.
- W2055443337 abstract "In May 2006, a serious environmental contamination with perfluorinated compounds (PFCs) became evident in a rural area of North Rhine-Westphalia (NRW) (Region Sauerland), Germany. In autumn 2006, we performed a human biomonitoring study in which a 4–8-fold increase in perfluorooctanoate (PFOA)-plasma concentrations of children, their mothers and men living in Arnsberg (District Hochsauerlandkreis, NRW) was observed compared with a reference population. The exposure was clearly related to the consumption of PFOA-contaminated tap water. However, there is no clear information on the duration of this contamination. The current investigation involves the analysis of PFCs in 30 blood samples of young adults (age 20–31 years) who had ever lived in the affected area. The samples were taken between 1977 and 2004 and stored at the German Environmental Specimen Bank for Human Tissues. Analyses of PFOA, perfluoroctanesulfonate (PFOS), perfluorohexanoate (PFHxA), perfluorohexanesulfonate (PFHxS), perfluoropentanoate (PFPA) and perfluorobutanesulfonate (PFBS) in blood plasma were performed by solid-phase extraction, HPLC and MS/MS detection. PFOA values (median, range) were 6.1, 1.7–40.7 μg/l, PFOS values were 18.8, 8.1–150.7 μg/l and PFHxS values were 1.7, 0.5–4.6 μg/l. The concentrations of PFHxA, PFPA and PFBS in plasma were all below limit of detection. Time-trend analysis showed that between 1977 and 2004 PFOA and PFOS levels remained fairly stable. PFOS and PFOA levels were in the range of current background levels of the general population. In contrast, PFHxS plasma levels have steadily increased since 1977. There was a close association between PFOS and PFOA-plasma levels. From this pilot study there are no indications for an increased exposure to PFCs of residents in Arnsberg in the years 1977–2004 prior to the contamination in 2006." @default.
- W2055443337 created "2016-06-24" @default.
- W2055443337 creator A5023083473 @default.
- W2055443337 creator A5026286546 @default.
- W2055443337 creator A5028375247 @default.
- W2055443337 creator A5048770241 @default.
- W2055443337 creator A5058921051 @default.
- W2055443337 creator A5061446816 @default.
- W2055443337 creator A5063131771 @default.
- W2055443337 creator A5064991508 @default.
- W2055443337 date "2009-03-01" @default.
- W2055443337 modified "2023-10-10" @default.
- W2055443337 title "Preliminary observations on perfluorinated compounds in plasma samples (1977–2004) of young German adults from an area with perfluorooctanoate-contaminated drinking water" @default.
- W2055443337 cites W1974752895 @default.
- W2055443337 cites W1975902105 @default.
- W2055443337 cites W1990949052 @default.
- W2055443337 cites W1996863157 @default.
- W2055443337 cites W2013684769 @default.
- W2055443337 cites W2016420872 @default.
- W2055443337 cites W2016627968 @default.
- W2055443337 cites W2041925174 @default.
- W2055443337 cites W2042880426 @default.
- W2055443337 cites W2057199097 @default.
- W2055443337 cites W2077364059 @default.
- W2055443337 cites W2124415169 @default.
- W2055443337 doi "https://doi.org/10.1016/j.ijheh.2008.04.008" @default.
- W2055443337 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18550432" @default.
- W2055443337 hasPublicationYear "2009" @default.
- W2055443337 type Work @default.
- W2055443337 sameAs 2055443337 @default.
- W2055443337 citedByCount "56" @default.
- W2055443337 countsByYear W20554433372012 @default.
- W2055443337 countsByYear W20554433372013 @default.
- W2055443337 countsByYear W20554433372014 @default.
- W2055443337 countsByYear W20554433372015 @default.
- W2055443337 countsByYear W20554433372016 @default.
- W2055443337 countsByYear W20554433372017 @default.
- W2055443337 countsByYear W20554433372018 @default.
- W2055443337 countsByYear W20554433372019 @default.
- W2055443337 countsByYear W20554433372020 @default.
- W2055443337 countsByYear W20554433372022 @default.
- W2055443337 countsByYear W20554433372023 @default.
- W2055443337 crossrefType "journal-article" @default.
- W2055443337 hasAuthorship W2055443337A5023083473 @default.
- W2055443337 hasAuthorship W2055443337A5026286546 @default.
- W2055443337 hasAuthorship W2055443337A5028375247 @default.
- W2055443337 hasAuthorship W2055443337A5048770241 @default.
- W2055443337 hasAuthorship W2055443337A5058921051 @default.
- W2055443337 hasAuthorship W2055443337A5061446816 @default.
- W2055443337 hasAuthorship W2055443337A5063131771 @default.
- W2055443337 hasAuthorship W2055443337A5064991508 @default.
- W2055443337 hasConcept C107872376 @default.
- W2055443337 hasConcept C109051061 @default.
- W2055443337 hasConcept C112570922 @default.
- W2055443337 hasConcept C185592680 @default.
- W2055443337 hasConcept C18903297 @default.
- W2055443337 hasConcept C2775979320 @default.
- W2055443337 hasConcept C2908647359 @default.
- W2055443337 hasConcept C2909167518 @default.
- W2055443337 hasConcept C43617362 @default.
- W2055443337 hasConcept C4725764 @default.
- W2055443337 hasConcept C71924100 @default.
- W2055443337 hasConcept C81426234 @default.
- W2055443337 hasConcept C86803240 @default.
- W2055443337 hasConcept C99454951 @default.
- W2055443337 hasConceptScore W2055443337C107872376 @default.
- W2055443337 hasConceptScore W2055443337C109051061 @default.
- W2055443337 hasConceptScore W2055443337C112570922 @default.
- W2055443337 hasConceptScore W2055443337C185592680 @default.
- W2055443337 hasConceptScore W2055443337C18903297 @default.
- W2055443337 hasConceptScore W2055443337C2775979320 @default.
- W2055443337 hasConceptScore W2055443337C2908647359 @default.
- W2055443337 hasConceptScore W2055443337C2909167518 @default.
- W2055443337 hasConceptScore W2055443337C43617362 @default.
- W2055443337 hasConceptScore W2055443337C4725764 @default.
- W2055443337 hasConceptScore W2055443337C71924100 @default.
- W2055443337 hasConceptScore W2055443337C81426234 @default.
- W2055443337 hasConceptScore W2055443337C86803240 @default.
- W2055443337 hasConceptScore W2055443337C99454951 @default.
- W2055443337 hasIssue "2" @default.
- W2055443337 hasLocation W20554433371 @default.
- W2055443337 hasLocation W20554433372 @default.
- W2055443337 hasOpenAccess W2055443337 @default.
- W2055443337 hasPrimaryLocation W20554433371 @default.
- W2055443337 hasRelatedWork W2008390761 @default.
- W2055443337 hasRelatedWork W2097389601 @default.
- W2055443337 hasRelatedWork W2212800452 @default.
- W2055443337 hasRelatedWork W2334365126 @default.
- W2055443337 hasRelatedWork W2392894710 @default.
- W2055443337 hasRelatedWork W2734403959 @default.
- W2055443337 hasRelatedWork W2907701505 @default.
- W2055443337 hasRelatedWork W2980253184 @default.
- W2055443337 hasRelatedWork W4312018395 @default.
- W2055443337 hasRelatedWork W4318066125 @default.
- W2055443337 hasVolume "212" @default.
- W2055443337 isParatext "false" @default.
- W2055443337 isRetracted "false" @default.
- W2055443337 magId "2055443337" @default.