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- W2055488085 abstract "Measuring vitamin D and its regulating hormones in the serum might be an accurate method for assessment of rheumatoid arthritis (RA) activity. We tested the hypothesis that the serum levels of vitamin D and parathyroid hormone (PTH) are associated with the grade of disease activity in an unselected cohort of patients with RA.A total of 158 patients who met the American College of Rheumatology criteria for RA were examined and categorized as the patients with the active RA (n = 87) and silent RA (n = 71). Blood samples were obtained after at least eight-hour overnight fasting and the levels of 25-OH-vitamin D and PTH were measured.The levels of the vitamin D in patients with active RA were significantly lower than in those with silent RA (49.38±38.21 versus 64.64±43.61 nmol/l; p = 0.022). The PTH serum level lower than the normal range (< 0.8 nmol/l) was statistically observed similar in the active RA group compared with another ones (10.3 % versus 4.2 %, p = 0.149). Serum levels of vitamin D and PTH were not influenced by patients' gender and age as well as the duration of disease.Serum level of vitamin D was inversely related to RA activity and this relationship might be independent of PTH secretion or activity." @default.
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- W2055488085 date "2012-01-01" @default.
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- W2055488085 title "Relationship between disease activity and serum levels of vitamin D and parathyroid hormone in rheumatoid arthritis" @default.
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- W2055488085 doi "https://doi.org/10.4149/endo_2012_02_61" @default.
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