Matches in SemOpenAlex for { <https://semopenalex.org/work/W2055494556> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2055494556 endingPage "151" @default.
- W2055494556 startingPage "141" @default.
- W2055494556 abstract "Glutathione S-transferases (GST) are phase II biotransformation enzymes influenced by exposure to foreign compounds and are proposed as biomarkers of environmental pollution. The hepatic and renal cytosolic GST isoenzymes from juvenile Atlantic eels were isolated and partially characterized. In both organs, three different GST isoenzymes were purified using HPLC and the final subcellular purified fraction resulted in enzymatic subunits of approximately 24 500 Da. Total GST activity was significantly higher towards the substrate 1-chloro-2,4-dinitrobenzene (CDNB) than the ethacrynic acid (ETHA). Induction of isoenzymes of GST was studied after intraperitoneal treatment with a single dose (25 mg/kg bw) of a polychlorinated biphenyls mixture. In the hepatic cytosol, an inductory effect on the major enzymatic isoform was observed when comparing treated with control eels. This was directly related to statistically significant (P<0.05) differences in total GST activity toward the CDNB between treated and control groups, with an increase of 33.6% of GST total activity measured in the last subcellular purified samples. In the kidney cytosol, PCB treatment did not affect GST activity. Significant differences were observed when analyzing the effect of PCB treatment on the main GST subunit height (retention time of 27 min). These results indicate that hepatic GST profiles could be considered as a good tool in environmental studies as specific biomarkers of contamination." @default.
- W2055494556 created "2016-06-24" @default.
- W2055494556 creator A5035040830 @default.
- W2055494556 creator A5043392267 @default.
- W2055494556 creator A5085068679 @default.
- W2055494556 date "2002-10-01" @default.
- W2055494556 modified "2023-10-03" @default.
- W2055494556 title "Induction of cytosolic Glutathione S-transferases from Atlantic eel (Anguilla anguilla) after intraperitoneal treatment with polychlorinated biphenyls" @default.
- W2055494556 cites W1758121554 @default.
- W2055494556 cites W1981541180 @default.
- W2055494556 cites W1981747037 @default.
- W2055494556 cites W1988627392 @default.
- W2055494556 cites W2007765114 @default.
- W2055494556 cites W2029700688 @default.
- W2055494556 cites W2040286580 @default.
- W2055494556 cites W2062933298 @default.
- W2055494556 cites W2066439231 @default.
- W2055494556 cites W2068392092 @default.
- W2055494556 cites W2081741294 @default.
- W2055494556 cites W2082497364 @default.
- W2055494556 cites W2088476090 @default.
- W2055494556 cites W2100837269 @default.
- W2055494556 cites W297484289 @default.
- W2055494556 cites W4234315600 @default.
- W2055494556 cites W4239878971 @default.
- W2055494556 cites W89153688 @default.
- W2055494556 doi "https://doi.org/10.1016/s0048-9697(02)00130-4" @default.
- W2055494556 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12389786" @default.
- W2055494556 hasPublicationYear "2002" @default.
- W2055494556 type Work @default.
- W2055494556 sameAs 2055494556 @default.
- W2055494556 citedByCount "17" @default.
- W2055494556 countsByYear W20554945562012 @default.
- W2055494556 countsByYear W20554945562013 @default.
- W2055494556 countsByYear W20554945562014 @default.
- W2055494556 countsByYear W20554945562016 @default.
- W2055494556 countsByYear W20554945562018 @default.
- W2055494556 countsByYear W20554945562022 @default.
- W2055494556 crossrefType "journal-article" @default.
- W2055494556 hasAuthorship W2055494556A5035040830 @default.
- W2055494556 hasAuthorship W2055494556A5043392267 @default.
- W2055494556 hasAuthorship W2055494556A5085068679 @default.
- W2055494556 hasConcept C115448650 @default.
- W2055494556 hasConcept C119795356 @default.
- W2055494556 hasConcept C181199279 @default.
- W2055494556 hasConcept C185592680 @default.
- W2055494556 hasConcept C2776907368 @default.
- W2055494556 hasConcept C2780159080 @default.
- W2055494556 hasConcept C43617362 @default.
- W2055494556 hasConcept C538909803 @default.
- W2055494556 hasConcept C55493867 @default.
- W2055494556 hasConcept C86803240 @default.
- W2055494556 hasConcept C98274493 @default.
- W2055494556 hasConcept C98539663 @default.
- W2055494556 hasConceptScore W2055494556C115448650 @default.
- W2055494556 hasConceptScore W2055494556C119795356 @default.
- W2055494556 hasConceptScore W2055494556C181199279 @default.
- W2055494556 hasConceptScore W2055494556C185592680 @default.
- W2055494556 hasConceptScore W2055494556C2776907368 @default.
- W2055494556 hasConceptScore W2055494556C2780159080 @default.
- W2055494556 hasConceptScore W2055494556C43617362 @default.
- W2055494556 hasConceptScore W2055494556C538909803 @default.
- W2055494556 hasConceptScore W2055494556C55493867 @default.
- W2055494556 hasConceptScore W2055494556C86803240 @default.
- W2055494556 hasConceptScore W2055494556C98274493 @default.
- W2055494556 hasConceptScore W2055494556C98539663 @default.
- W2055494556 hasIssue "1-3" @default.
- W2055494556 hasLocation W20554945561 @default.
- W2055494556 hasLocation W20554945562 @default.
- W2055494556 hasOpenAccess W2055494556 @default.
- W2055494556 hasPrimaryLocation W20554945561 @default.
- W2055494556 hasRelatedWork W1491965422 @default.
- W2055494556 hasRelatedWork W198637973 @default.
- W2055494556 hasRelatedWork W2025962977 @default.
- W2055494556 hasRelatedWork W2031168995 @default.
- W2055494556 hasRelatedWork W2060038873 @default.
- W2055494556 hasRelatedWork W2091395663 @default.
- W2055494556 hasRelatedWork W2138971261 @default.
- W2055494556 hasRelatedWork W2342912340 @default.
- W2055494556 hasRelatedWork W2376216423 @default.
- W2055494556 hasRelatedWork W2505529253 @default.
- W2055494556 hasVolume "297" @default.
- W2055494556 isParatext "false" @default.
- W2055494556 isRetracted "false" @default.
- W2055494556 magId "2055494556" @default.
- W2055494556 workType "article" @default.