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- W2055495655 abstract "Native and reconstituted nucleoprotamines and sperm nucleus itself give essentially identical X-ray diffraction patterns which are also similar to the pattern of DNA (Wilkins et al., 1953; Wilkins and Randall, 1953; Feughelman et al., 1955; Wilkins, 1956). Infrared absorption spectra show that the DNA. portion of DNA-protamine has a structure identical to that of the free DNA molecule [Bradbury et al., 1962 (1)]. Therefore DNA in vivo is presumably in the B form, whether or not protamine is bound to it. Judging from the hydrogen-deuterium exchange reaction [Haggis, 1957; Bradbury et al., 1962 (1)] and infrared absorption spectra, the structure of the protamine portion in the DNA-protamine complex is supposed to be a partly extended form, intermediate between the α-helix and fully extended β-structure [Bradbury et al., 1962 (1)]. Accordingly, in the nucleoprotamine molecule, B-form DNA and partly extended protamine are thought to combine in some way so that basic groups in protamine are bound to the phosphate groups of DNA (Feughelman et al., 1955; Wilkins, 1956). The physical structure of nucleoprotamine has not yet been established, but three models have been proposed for it." @default.
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- W2055495655 date "1973-01-01" @default.
- W2055495655 modified "2023-09-29" @default.
- W2055495655 title "Chemical Structure of Nucleoprotamines and Protamines" @default.
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- W2055495655 doi "https://doi.org/10.1007/978-3-642-46294-8_6" @default.
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