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• W2055520535 abstract "Thirteen gallic acid derivatives including five new gallotannins, named maplexins A-E, were isolated from red maple (Acer rubrum) stems. The compounds were identified by spectral analyses. The maplexins varied in number and location of galloyl groups attached to 1,5-anhydro-d-glucitol. The isolates were evaluated for α-glucosidase inhibitory and antioxidant activities. Maplexin E, the first compound identified with three galloyl groups linked to three different positions of 1,5-anhydro-d-glucitol, was 20 fold more potent than the α-glucosidase inhibitory drug, Acarbose (IC(50)=8 vs 160 μM). Structure-activity related studies suggested that both number and position of galloyls attached to 1,5-anhydro-d-glucitol were important for α-glucosidase inhibition." @default.
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• W2055520535 date "2012-01-01" @default.
• W2055520535 modified "2023-10-18" @default.
• W2055520535 title "Maplexins, new α-glucosidase inhibitors from red maple (Acer rubrum) stems" @default.
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• W2055520535 doi "https://doi.org/10.1016/j.bmcl.2011.10.073" @default.
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