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- W2055552103 abstract "It has been generally acknowledged that the module structure of protein interaction networks plays a crucial role with respect to the functional understanding of these networks. In this paper, we study evolutionary aspects of the module structure of protein interaction networks, which forms a mesoscopic level of description with respect to the architectural principles of networks. The purpose of this paper is to investigate limitations of well known gene duplication models by showing that these models are lacking crucial structural features present in protein interaction networks on a mesoscopic scale. This observation reveals our incomplete understanding of the structural evolution of protein networks on the module level." @default.
- W2055552103 created "2016-06-24" @default.
- W2055552103 creator A5057625030 @default.
- W2055552103 date "2012-04-18" @default.
- W2055552103 modified "2023-09-27" @default.
- W2055552103 title "Limitations of Gene Duplication Models: Evolution of Modules in Protein Interaction Networks" @default.
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- W2055552103 doi "https://doi.org/10.1371/journal.pone.0035531" @default.
- W2055552103 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3329483" @default.
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